Results 31 to 40 of about 28,756 (283)

Optogenetics in Brain Research: From a Strategy to Investigate Physiological Function to a Therapeutic Tool

open access: yesPhotonics, 2019
Dissecting the functional roles of neuronal circuits and their interaction is a crucial step in basic neuroscience and in all the biomedical field. Optogenetics is well-suited to this purpose since it allows us to study the functionality of neuronal ...
Elena Montagni   +3 more
doaj   +1 more source

The Roles of Optogenetics and Technology in Neurobiology: A Review

open access: yesFrontiers in Aging Neuroscience, 2022
Optogenetic is a technique that combines optics and genetics to control specific neurons. This technique usually uses adenoviruses that encode photosensitive protein. The adenovirus may concentrate in a specific neural region.
Wenqing Chen   +13 more
doaj   +1 more source

Rods progressively escape saturation to drive visual responses in daylight conditions

open access: yesNature Communications, 2017
Rod photoreceptors are thought to be saturated under bright light. Here, the authors describe the physiological parameters that mediate response saturation of rod photoreceptors in mouse retina, and show that rods can drive visual responses in photopic ...
Alexandra Tikidji-Hamburyan   +14 more
doaj   +1 more source

Prospects for optogenetic augmentation of brain function

open access: yesFrontiers in Systems Neuroscience, 2015
The ability to optically control neural activity opens up possibilities for the restoration of normal function following neurological disorders. The temporal precision, spatial resolution and neuronal specificity that optogenetics offers is unequalled by
Sarah eJarvis   +3 more
doaj   +1 more source

Bioluminescence-Driven Optogenetics

open access: yesLife, 2020
Bioluminescence-based technologies are among the most commonly used methods to quantify and visualise physiology at the cellular and organismal levels.
Macià Sureda-Vives, Karen S. Sarkisyan
doaj   +1 more source

AAV1 is the optimal viral vector for optogenetic experiments in pigeons (Columba livia)

open access: yesCommunications Biology, 2021
Rook et al. establish a viral gene transfer system to perform optogenetics in pigeons. They deliver ChR2 via AAV1 into the visual entopallium and show its behavioral relevance for contrast perception, verifying the applicability of optogenetics in an ...
Noemi Rook   +6 more
doaj   +1 more source

Optogenetics in epilepsy [PDF]

open access: yesNeurosurgical Focus, 2013
Optogenetics, the use of light to stimulate or inhibit neural circuits via viral transduction of protein channels, has emerged as a possible method of treating epilepsy. By introducing viral vectors carrying algal-derived cation or anion channels, known as opsins, neurons that initiate or propagate seizures may be silenced.
J Nicole, Bentley   +3 more
openaire   +2 more sources

Applications and challenges of rhodopsin-based optogenetics in biomedicine

open access: yesFrontiers in Neuroscience, 2022
Optogenetics is an emerging bioengineering technology that has been rapidly developed in recent years by cross-integrating optics, genetic engineering, electrophysiology, software control, and other disciplines.
Hanci Zhang   +9 more
doaj   +1 more source

Optogenetics: Controlling Neurons with Light for Brain Disorders

open access: yes, 2023
Optogenetics is a groundbreaking interdisciplinary field that has revolutionized neuroscience by allowing precise control of neural activity using light.
Driao Kaauser
core   +1 more source

Olfactory Optogenetics: Light Illuminates the Chemical Sensing Mechanisms of Biological Olfactory Systems

open access: yesBiosensors, 2021
The mammalian olfactory system has an amazing ability to distinguish thousands of odorant molecules at the trace level. Scientists have made great achievements on revealing the olfactory sensing mechanisms in decades; even though many issues need ...
Ping Zhu   +6 more
doaj   +1 more source

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