Results 1 to 10 of about 153,158 (120)
Scientific Reports, 2021 Quantitatively comparing brain-wide connectivity of different types of neuron is of vital importance in understanding the function of the mammalian cortex.
Alexander P. Y. Brown +5 more
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Transient photocurrents in a subthreshold evidence accumulator accelerate perceptual decisions
Nature Communications, 2023 Perceptual decisions are complete when a continuously updated score of sensory evidence reaches a threshold. In Drosophila, αβ core Kenyon cells (αβc KCs) of the mushroom bodies integrate odor-evoked synaptic inputs to spike threshold at rates that ...
Timothy L. H. Wong +2 more
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A single-cell transcriptomic atlas of the adult Drosophila ventral nerve cord
eLife, 2020 The Drosophila ventral nerve cord (VNC) receives and processes descending signals from the brain to produce a variety of coordinated locomotor outputs. It also integrates sensory information from the periphery and sends ascending signals to the brain. We
Aaron M Allen +6 more
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Frontiers in Neuroanatomy, 2021 Synaptic loss in Alzheimer's disease (AD) is strongly correlated with cognitive impairment. Accumulating evidence indicates that amyloid pathology leads to synaptic degeneration and mitochondrial damage in AD. However, it remains unclear whether synapses
Na-young Seo +7 more
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Emergence of local and global synaptic organization on cortical dendrites
Nature Communications, 2021 Synaptic inputs on neuronal dendrites exhibit remarkable organization at different spatial scales, which emerges during the early postnatal development.
Jan H. Kirchner, Julijana Gjorgjieva
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Nature Communications, 2023 In the mammalian visual system, the ventral lateral geniculate nucleus (vLGN) of the thalamus receives salient visual input from the retina and sends prominent GABAergic axons to the superior colliculus (SC).
Zhong Li +9 more
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Developmental depression-to-facilitation shift controls excitation-inhibition balance
Communications Biology, 2022 Using computational modelling this study proposes that the commonly observed depression-to-facilitation shift across development controls excitation-inhibition balance in the brain.
David W. Jia +2 more
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Spontaneous activity in whisker-innervating region of neonatal mouse trigeminal ganglion
Scientific Reports, 2022 Spontaneous activity during the early postnatal period is thought to be crucial for the establishment of mature neural circuits. It remains unclear if the peripheral structure of the developing somatosensory system exhibits spontaneous activity, similar ...
Piu Banerjee +6 more
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Rapid odor processing by layer 2 subcircuits in lateral entorhinal cortex
eLife, 2022 Olfactory information is encoded in lateral entorhinal cortex (LEC) by two classes of layer 2 (L2) principal neurons: fan and pyramidal cells. However, the functional properties of L2 cells and how they contribute to odor coding are unclear.
Sebastian H Bitzenhofer +3 more
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Cellular diversity in the Drosophila midbrain revealed by single-cell transcriptomics
eLife, 2018 To understand the brain, molecular details need to be overlaid onto neural wiring diagrams so that synaptic mode, neuromodulation and critical signaling operations can be considered.
Vincent Croset +2 more
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