Results 1 to 10 of about 177,791 (315)

Analysis of segmentation ontology reveals the similarities and differences in connectivity onto L2/3 neurons in mouse V1

open access: yesScientific Reports, 2021
Quantitatively comparing brain-wide connectivity of different types of neuron is of vital importance in understanding the function of the mammalian cortex.
Alexander P. Y. Brown   +5 more
doaj   +1 more source

Transient photocurrents in a subthreshold evidence accumulator accelerate perceptual decisions

open access: yesNature Communications, 2023
Perceptual decisions are complete when a continuously updated score of sensory evidence reaches a threshold. In Drosophila, αβ core Kenyon cells (αβc KCs) of the mushroom bodies integrate odor-evoked synaptic inputs to spike threshold at rates that ...
Timothy L. H. Wong   +2 more
doaj   +1 more source

Selective Regional Loss of Cortical Synapses Lacking Presynaptic Mitochondria in the 5xFAD Mouse Model

open access: yesFrontiers in Neuroanatomy, 2021
Synaptic loss in Alzheimer's disease (AD) is strongly correlated with cognitive impairment. Accumulating evidence indicates that amyloid pathology leads to synaptic degeneration and mitochondrial damage in AD. However, it remains unclear whether synapses
Na-young Seo   +7 more
doaj   +1 more source

A single-cell transcriptomic atlas of the adult Drosophila ventral nerve cord

open access: yeseLife, 2020
The Drosophila ventral nerve cord (VNC) receives and processes descending signals from the brain to produce a variety of coordinated locomotor outputs. It also integrates sensory information from the periphery and sends ascending signals to the brain. We
Aaron M Allen   +6 more
doaj   +1 more source

Emergence of local and global synaptic organization on cortical dendrites

open access: yesNature Communications, 2021
Synaptic inputs on neuronal dendrites exhibit remarkable organization at different spatial scales, which emerges during the early postnatal development.
Jan H. Kirchner, Julijana Gjorgjieva
doaj   +1 more source

The role of zebrafish (Danio rerio) in dissecting the genetics and neural circuits of executive function [PDF]

open access: yes, 2013
Zebrafish have great potential to contribute to our understanding of behavioural genetics and thus to contribute to our understanding of the aetiology of psychiatric disease.
Brock, AJ   +15 more
core   +1 more source

Enhancement and contextual modulation of visuospatial processing by thalamocollicular projections from ventral lateral geniculate nucleus

open access: yesNature Communications, 2023
In the mammalian visual system, the ventral lateral geniculate nucleus (vLGN) of the thalamus receives salient visual input from the retina and sends prominent GABAergic axons to the superior colliculus (SC).
Zhong Li   +9 more
doaj   +1 more source

Developmental depression-to-facilitation shift controls excitation-inhibition balance

open access: yesCommunications Biology, 2022
Using computational modelling this study proposes that the commonly observed depression-to-facilitation shift across development controls excitation-inhibition balance in the brain.
David W. Jia   +2 more
doaj   +1 more source

An Energy-Efficient, Dynamic Voltage Scaling Neural Stimulator for a Proprioceptive Prosthesis [PDF]

open access: yes, 2012
This paper presents an energy-efficient neural stimulator capable of providing charge-balanced asymmetric pulses. Power consumption is reduced by implementing a fully-integrated DC-DC converter that uses a reconfigurable switched capacitor topology to ...
Ian Williams   +3 more
core   +1 more source

Spontaneous activity in whisker-innervating region of neonatal mouse trigeminal ganglion

open access: yesScientific Reports, 2022
Spontaneous activity during the early postnatal period is thought to be crucial for the establishment of mature neural circuits. It remains unclear if the peripheral structure of the developing somatosensory system exhibits spontaneous activity, similar ...
Piu Banerjee   +6 more
doaj   +1 more source

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