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Neural circuits revealed [PDF]
The appropriate function of the nervous system relies on precise patterns of connectivity among hundreds to billions of neurons across different biological systems. Evolutionarily conserved patterns of neural circuit organization and connectivity between morphologically and functionally diverse sets of neurons emerge from a remarkably robust set of ...
Soiza-Reilly, Mariano +2 more
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Emotions are fundamental to our experience and behavior, affecting and motivating all aspects of our lives. Scientists of various disciplines have been fascinated by emotions for centuries, yet even today vigorous debates abound about how to define emotions and how to best study their neural underpinnings.
Malezieux, Meryl +2 more
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Quantitatively comparing brain-wide connectivity of different types of neuron is of vital importance in understanding the function of the mammalian cortex.
Alexander P. Y. Brown +5 more
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This Frontiers Research Topic on ‘Neural Circuits: Japan’ explores the diversity of neural circuit research occurring across Japan by innovative researchers using cutting-edge approaches. This issue has brought together papers revealing the development, structure, and physiology of neuronal circuits involved in sensory perception, sleep and wakefulness,
Kawaguchi, Yasuo, Kano, Masanobu
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Transient photocurrents in a subthreshold evidence accumulator accelerate perceptual decisions
Perceptual decisions are complete when a continuously updated score of sensory evidence reaches a threshold. In Drosophila, αβ core Kenyon cells (αβc KCs) of the mushroom bodies integrate odor-evoked synaptic inputs to spike threshold at rates that ...
Timothy L. H. Wong +2 more
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Targeting Neural Circuits [PDF]
Optogenetic methodology enables direct targeting of specific neural circuit elements for inhibition or excitation while spanning timescales from the acute (milliseconds) to the chronic (many days or more). Although the impact of this temporal versatility and cellular specificity has been greater for basic science than clinical research, it is natural ...
Priyamvada, Rajasethupathy +2 more
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Neural Circuits of Interoception
The present paper considers recent progress in our understanding of the afferent/ascending neural pathways and neural circuits of interoception. Of particular note is the extensive role of rostral neural systems, including cortical systems, in the recognition of internal body states, and the reciprocal role of efferent/descending systems in the ...
Gary G, Berntson, Sahib S, Khalsa
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Synaptic loss in Alzheimer's disease (AD) is strongly correlated with cognitive impairment. Accumulating evidence indicates that amyloid pathology leads to synaptic degeneration and mitochondrial damage in AD. However, it remains unclear whether synapses
Na-young Seo +7 more
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A single-cell transcriptomic atlas of the adult Drosophila ventral nerve cord
The Drosophila ventral nerve cord (VNC) receives and processes descending signals from the brain to produce a variety of coordinated locomotor outputs. It also integrates sensory information from the periphery and sends ascending signals to the brain. We
Aaron M Allen +6 more
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