Results 11 to 20 of about 162,818 (217)

Rapid odor processing by layer 2 subcircuits in lateral entorhinal cortex

open access: yeseLife, 2022
Olfactory information is encoded in lateral entorhinal cortex (LEC) by two classes of layer 2 (L2) principal neurons: fan and pyramidal cells. However, the functional properties of L2 cells and how they contribute to odor coding are unclear.
Sebastian H Bitzenhofer   +3 more
doaj   +1 more source

Adaptive Learning Gabor Filter for Finger-Vein Recognition

open access: yesIEEE Access, 2019
Presently, finger-vein recognition is a new research direction in the field of biometric recognition. The Gabor filter has been extensively used for finger-vein recognition; however, its parameters are difficult to adjust.
Yakun Zhang   +5 more
doaj   +1 more source

Shining a light on the origin of fly species

open access: yeseLife, 2020
Natural light gradients within a habitat may have helped form new fly species that have differing preferences for light.
Hui Gong, Lucia Prieto-Godino
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Recurrent circuits within medial entorhinal cortex superficial layers support grid cell firing

open access: yesNature Communications, 2018
Medial entorhinal cortex (mEC) neurons encode various navigation parameters such as speed, head direction, as well as grid cells. Here, the authors demonstrate that brief disruption of the local activity in mEC specifically affects grid cell tuning.
Ipshita Zutshi   +5 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Context-dependent serotonin signaling links dietary quality to foraging decisions

open access: yesNature Communications
Animals sense their metabolic needs to guide adaptive behaviors partly through serotonin, a neurotransmitter associated with feeding in many species.
Likui Feng   +5 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Convergent direct and indirect cortical streams shape avoidance decisions in mice via the midline thalamus

open access: yesNature Communications
Current concepts of corticothalamic organization in the mammalian brain are mainly based on sensory systems, with less focus on circuits for higher-order cognitive functions.
Jun Ma   +6 more
doaj   +1 more source

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