Results 41 to 50 of about 391,417 (288)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Metastability, Criticality and Phase Transitions in brain and its Models [PDF]
, 2006 This essay extends the previously deposited paper "Oscillations, Metastability and Phase Transitions" to incorporate the theory of Self-organizing Criticality.
Werner, MD Gerhard
core
Models wagging the dog: are circuits constructed with disparate parameters? [PDF]
, 2007 In a recent article, Prinz, Bucher, and Marder (2004) addressed the fundamental question of whether neural systems are built with a fixed blueprint of tightly controlled parameters or in a way in which properties can vary largely from one individual to ...
Allen I. Selverston +4 more
core +2 more sources
Vertebrate versus invertebrate neural circuits [PDF]
Current Biology, 2013 SummaryThe recent Cell Symposium ‘Genes, Circuits and Behavior’ brought together researchers working on neural circuits in vertebrate and invertebrate species. In the interest of fostering communication across the ‘backbone-divide’, we asked a number of neuroscientists from both camps for their views on the extent to which insights obtained from ...
Katz, P. +10 more
openaire +3 more sources
History-based action selection bias in posterior parietal cortex
Nature Communications, 2017 Past outcomes modulate activity in a diverse set of brain regions however their precise influence on decisions is not known. Here the authors show that posterior parietal cortex neurons encode history-related signals between trials and optogenetic ...
Eun Jung Hwang +3 more
doaj +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Context-dependent serotonin signaling links dietary quality to foraging decisions
Nature CommunicationsAnimals sense their metabolic needs to guide adaptive behaviors partly through serotonin, a neurotransmitter associated with feeding in many species.
Likui Feng +5 more
doaj +1 more source
Molecular Brain, 2022 Somatostatin-expressing interneurons (SOM-INs) are a major subpopulation of GABAergic cells in CA1 hippocampus that receive excitation from pyramidal cells (PCs) and provide feedback control of synaptic inputs onto PC dendrites.
Ève Honoré +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
TrakEM2 Software for Neural Circuit Reconstruction
PLoS ONE, 2012 A key challenge in neuroscience is the expeditious reconstruction of neuronal circuits. For model systems such as Drosophila and C. elegans, the limiting step is no longer the acquisition of imagery but the extraction of the circuit from images. For this purpose, we designed a software application, TrakEM2, that addresses the systematic reconstruction ...
Cardona, Albert +8 more
openaire +10 more sources