Results 41 to 50 of about 28,756 (283)
Behavioral optogenetics in nonhuman primates; a psychological perspective
Current Research in Neurobiology, 2023 Optogenetics has been a promising and developing technology in systems neuroscience throughout the past decade. It has been difficult though to reliably establish the potential behavioral effects of optogenetic perturbation of the neural activity in ...
Arash Afraz
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A Light Wand to Untangle the Myocardial Cell Network
Methods and Protocols, 2019 The discovery of optogenetics has revolutionized research in neuroscience by providing the tools for noninvasive, cell-type selective modulation of membrane potential and cellular function in vitro and in vivo. Rhodopsin-based optogenetics has later been
Tania Zaglia +2 more
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Optogenetics: Emerging strategies for neuropathic pain treatment
Frontiers in Neurology, 2022 Neuropathic pain (NP) is a chronic health condition that presents a significant burden on patients, society, and even healthcare systems. However, in recent years, an emerging field in the treatment of neuropathic pain – optogenetic technology has dawned,
Siyu Li +3 more
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In Vivo Optogenetics Based on Heavy Metal-Free Photon Upconversion Nanoparticles [PDF]
Photon upconversion (UC) from red or near-infrared (NIR) light to blue light is promising for in vivo optogenetics. However, the examples of in vivo optogenetics have been limited to lanthanide inorganic UC nanoparticles, and there have been no examples ...
Jumpei, Kondo +8 more
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FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
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Optogenetics Therapy of Human Cancers
Zhongliu Fangzhi Yanjiu, 2018 The optogenetics approach uses a combination of genetic and optical methods to control the functions in specific cells of biological tissues. Since the control of neuronal activity by irradiating channelrhodopsin-2 with blue light was reported in 2005 ...
ZHANG Baihong, YUE Hongyun
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Analyzing efficacy, stability, and safety of AAV-mediated optogenetic hearing restoration in mice
Life Science Alliance, 2022 This longitudinal study revealed stable expression of the fast-gating channelrhodopsin f-Chrimson in cochlear neurons of mice over at least 2 yr upon a single postnatal AAV dosing of the cochlea.
Burak Bali +4 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu +7 more
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Herald of the Russian Academy of Sciences, 2019 In this article the authors discuss electronic and optogenetic approaches for degenerative (blind) retina prosthesis as the main strategies for the restoration of vision to blind people. Primary attention is devoted to the prospects of developing retinal prostheses for the blind using modern optogenetic methods, and rhodopsins, which are photosensitive
M. P. Kirpichnikov, М. А. Оstrovsky
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) is a minimally invasive therapy for drug‐resistant focal epilepsy. However, the relationship between specific seizure‐onset patterns (SOPs), particularly low‐voltage fast activity (LVFA), and postoperative scalp EEG normalization remains inadequately ...
Yi‐qing Yang +6 more
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