Results 11 to 20 of about 44,262 (332)

Optogenetics in Brain Research: From a Strategy to Investigate Physiological Function to a Therapeutic Tool [PDF]

Photonics, 2019
Dissecting the functional roles of neuronal circuits and their interaction is a crucial step in basic neuroscience and in all the biomedical field. Optogenetics is well-suited to this purpose since it allows us to study the functionality of neuronal ...
Elena Montagni, Francesco Resta, Anna Letizia Allegra Mascaro, Francesco Saverio Pavone   +3 more
doaj   +2 more sources

Emerging optogenetics technologies in biomedical applications

Smart Medicine, 2023
Optogenetics is a cutting‐edge technology that merges light control and genetics to achieve targeted control of tissue cells. Compared to traditional methods, optogenetics offers several advantages in terms of time and space precision, accuracy, and ...
Haozhen Ren, Yi Cheng, Gaolin Wen, Jinglin Wang, Min Zhou   +4 more
doaj   +1 more source

Advances in optogenetic studies of depressive-like behaviors and underlying neural circuit mechanisms

Frontiers in Psychiatry, 2022
BackgroundsThe neural circuit mechanisms underlying depression remain unclear. Recently optogenetics has gradually gained recognition as a novel technique to regulate the activity of neurons with light stimulation.
Shanshan Lin, Shanshan Lin, Yiwei Du, Yiwei Du, Yujie Xia, Yujie Xia, Yumeng Xie, Yumeng Xie, Ling Xiao, Ling Xiao, Gaohua Wang, Gaohua Wang   +11 more
doaj   +1 more source

Tools for Controlling Activity of Neural Circuits Can Boost Gastrointestinal Research [PDF]

, 2016
We thank Prof U. G. Knaus and T. C. Collin for critical reading of the manuscript. GA is supported by the European Crohn's and Colitis Organization (ECCO) (J/15/2) and by the National Childrens' Research Centre (K/12/1). GD is supported by the University
Aviello, Gabriella, D'Agostino, Giuseppe
core   +6 more sources

Optogenetics in primate cortical networks

Frontiers in Neuroanatomy, 2023
The implementation of optogenetics in studies on non-human primates has generally proven quite difficult, but recent successes have paved the way for its rapid increase.
Sam Merlin, Trichur Vidyasagar, Trichur Vidyasagar   +2 more
doaj   +1 more source

Optogenetics and deep brain stimulation neurotechnologies [PDF]

, 2015
Brain neural network is composed of densely packed, intricately wired neurons whose activity patterns ultimately give rise to every behavior, thought, or emotion that we experience. Over the past decade, a novel neurotechnique, optogenetics that combines
A Berndt, A Berndt, A Priori, AA Kuhn, AA Kuhn, AS Chuong, B Sauer, B Wingeier, BY Chow, BY Chow, C Bamann, D Luo, D Oesterhelt, D Oesterhelt, D Williams, ES Boyden, EY Uc, F Zhang, F Zhang, G Foffani, G Miesenbock, G Nagel, J Cavanaugh, J Mobley, J Volkmann, J Wells, J Wietek, JG Bernstein, JG Bernstein, JG Bernstein, JL Spudich, JL Spudich, JO Dostrovsky, JZ Tsien, L Bekar, L Madisen, LA Gunaydin, M Weinberger, M Weinberger, MC Rodriguez-Oroz, MJ Lehmkuhle, ML Welter, MM Doroudchi, O Yizhar, P Brown, P Silberstein, R Levy, R Levy, R Levy, R Waehler, S Zhao, TW Chen, VC Anderson, X Han, X Han, X Han, X Han, X Han, X Liu   +58 more
core   +2 more sources

Controlling protein stability with SULI, a highly sensitive tag for stabilization upon light induction

Nature Communications, 2023
Optogenetics tools for precise temporal and spatial control of protein abundance are valuable in studying diverse complex biological processes. In the present study, we engineer a monomeric tag of stabilization upon light induction (SULI) for yeast and ...
Miaowei Mao, Yajie Qian, Wenyao Zhang, Siyu Zhou, Zefeng Wang, Xianjun Chen, Yi Yang   +6 more
doaj   +1 more source

Nonparametric Causal Inference for Optogenetics: Sequential Excursion Effects for Dynamic Regimes. [PDF]

J Am Stat Assoc
Loewinger G, Levis AW, Pereira F.
europepmc   +2 more sources

Optical excitation and detection of neuronal activity [PDF]

, 2017
Optogenetics has emerged as an exciting tool for manipulating neural activity, which in turn, can modulate behavior in live organisms. However, detecting the response to the optical stimulation requires electrophysiology with physical contact or ...
Gillette, Martha, Hu, Chenfei, Kim, Taewoo, Nastasa, Viorel, Popescu, Gabriel, Sam, Richard, Sengupta, Parijat, Shan, Mingguang, Wang, Minqi   +8 more
core   +2 more sources

X-Optogenetics and U-Optogenetics: Feasibility and Possibilities

Photonics, 2015
Optogenetics is an established technique that uses visible light to modulate membrane voltage in neural cells. Although optogenetics allows researchers to study parts of the brain like never before, it is limited because it is invasive, and visible light
Rachel Berry, Matthew Getzin, Lars Gjesteby, Ge Wang   +3 more
doaj   +1 more source