Results 11 to 20 of about 21,147 (255)
Proceedings of the National Academy of Sciences, 2013 Biophysics; Genetic Engineering; Neuroscience; Optics; Vision ...
Sarah C P, Williams, Karl, Deisseroth
+7 more sources
New Phytologist, 2020 SummaryThe last two decades have witnessed the emergence of optogenetics; a field that has given researchers the ability to use light to control biological processes at high spatiotemporal and quantitative resolutions, in a reversible manner with minimal side‐effects.
Christie, John M., Zurbriggen, Matias D.
openaire +3 more sources
Current Opinion in Ophthalmology, 2015 In this review, we will discuss the recent developments in optogenetics and their potential applications in ophthalmology to restore vision in retinal degenerative diseases.In recent years, we have seen major advances in the field of optogenetics, providing us with novel opsins for potential applications in the retina.
Duebel, Jens +2 more
+6 more sources
Optogenetics in epilepsy [PDF]
Neurosurgical Focus, 2013 Optogenetics, the use of light to stimulate or inhibit neural circuits via viral transduction of protein channels, has emerged as a possible method of treating epilepsy. By introducing viral vectors carrying algal-derived cation or anion channels, known as opsins, neurons that initiate or propagate seizures may be silenced.
J Nicole, Bentley +3 more
openaire +2 more sources
Nature Communications, 2023 Optogenetics tools for precise temporal and spatial control of protein abundance are valuable in studying diverse complex biological processes. In the present study, we engineer a monomeric tag of stabilization upon light induction (SULI) for yeast and ...
Miaowei Mao +6 more
doaj +1 more source
Optogenetics in primate cortical networks
Frontiers in Neuroanatomy, 2023 The implementation of optogenetics in studies on non-human primates has generally proven quite difficult, but recent successes have paved the way for its rapid increase.
Sam Merlin +2 more
doaj +1 more source
Cell, 2010 Optogenetic methods use light to modulate the activities of target cells in vivo. By improving inter- and intracellular trafficking of light-sensitive switch proteins called opsins, Gradinaru et al. (2010) have developed a new generation of optogenetic tools capable of regulating the activity of targeted neurons with exquisite precision and efficiency.
Liu, Xu, Tonegawa, Susumu
openaire +4 more sources
Step Sequence is a Critical Gait Parameter of Unilateral 6-OHDA Parkinson's Rat Models
Cell Transplantation, 2017 Parkinson's disease is a progressive neurological disorder, marked by the loss of dopaminergic neurons in the nigrostriatal pathway that leads to abnormal gait, rigidity, slowness of movement, and tremor.
Heather A. Baldwin +4 more
doaj +1 more source
Photonics, 2019 Dissecting the functional roles of neuronal circuits and their interaction is a crucial step in basic neuroscience and in all the biomedical field. Optogenetics is well-suited to this purpose since it allows us to study the functionality of neuronal ...
Elena Montagni +3 more
doaj +1 more source
Prospects for optogenetic augmentation of brain function
Frontiers in Systems Neuroscience, 2015 The ability to optically control neural activity opens up possibilities for the restoration of normal function following neurological disorders. The temporal precision, spatial resolution and neuronal specificity that optogenetics offers is unequalled by
Sarah eJarvis +3 more
doaj +1 more source