Results 11 to 20 of about 25,913 (283)

Optogenetics.

open access: yesCurrent Opinion in Ophthalmology, 2015
International audienceIn this review, we will discuss the recent developments in optogenetics and their potential applications in ophthalmology to restore vision in retinal degenerative diseases.
Marazova, Katia   +2 more
core   +6 more sources

Optogenetics

open access: yes, 2017
Discovered little more than a decade ago, optogenetics - a revolutionary technique combining genetic and optical methods to observe and control the function of neurons - is now a widely used research tool. Optogenetics-driven research has led to insights

core   +4 more sources

Optogenetics [PDF]

open access: yesProceedings of the National Academy of Sciences, 2013
Biophysics; Genetic Engineering; Neuroscience; Optics; Vision ...
Sarah C P, Williams, Karl, Deisseroth
  +9 more sources

Optogenetics for Retinal Disorders

open access: yesJournal of Ophthalmic & Vision Research, 2014
Optogenetics is the use of genetic methods combined with optical technology to achieve gain or loss of function within neuronal circuits. The field of optogenetics has been rapidly expanding in efforts to restore visual function to blinding diseases such
Bradley S Henriksen   +2 more
doaj   +2 more sources

Design of a palette of SNAP-tag mimics of fluorescent proteins and their use as cell reporters

open access: yesCell Discovery, 2023
Naturally occurring fluorescent proteins (FPs) are the most widely used tools for tracking cellular proteins and sensing cellular events. Here, we chemically evolved the self-labeling SNAP-tag into a palette of SNAP-tag mimics of fluorescent proteins ...
Dasheng Zhang   +20 more
doaj   +1 more source

Group-based, autonomous, individualized training and testing of long-tailed macaques (Macaca fascicularis) in their home enclosure to a visuo-acoustic discrimination task

open access: yesFrontiers in Psychology, 2022
In recent years, the utility and efficiency of automated procedures for cognitive assessment in psychology and neuroscience have been demonstrated in non-human primates (NHP).
Jorge Cabrera-Moreno   +13 more
doaj   +1 more source

Flexible auditory training, psychophysics, and enrichment of common marmosets with an automated, touchscreen-based system

open access: yesNature Communications, 2022
The authors present a cage-based stand-alone platform for autonomous, standardized, and unsupervised training and testing of visuo-auditory-cued behaviours of common marmosets. The experiments do not require dietary restriction or social separation.
A. Calapai   +3 more
doaj   +1 more source

Monitoring NAD(H) and NADP(H) dynamics during organismal development with genetically encoded fluorescent biosensors

open access: yesCell Regeneration, 2022
Cell metabolism plays vital roles in organismal development, but it has been much less studied than transcriptional and epigenetic control of developmental programs.
Ting Li   +5 more
doaj   +1 more source

Cardiac optogenetics: shining light on signaling pathways. [PDF]

open access: yes, 2023
In the early 2000s, the field of neuroscience experienced a groundbreaking transformation with the advent of optogenetics. This innovative technique harnesses the properties of naturally occurring and genetically engineered rhodopsins to confer light ...
Schneider-Warme, Franziska   +2 more
core   +1 more source

Computational neuroscience meets optogenetics: Unlocking the brain’s secrets [PDF]

open access: yes, 2020
Working at the interface between engineering and neuroscience, Professor Simon Schultz and Dr Konstantin Nikolic at Imperial College London are developing tools to help us understand the intricate workings of the brain.
Nikolic, Konstantin, Schultz, Simon
core   +1 more source

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