Results 111 to 120 of about 58,764 (371)

Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley   +1 more source

Neuronal optogenetics as a new topic of technology assessment?

open access: yesTATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis
This article is intended as a sketchy reflection on the question of the extent to which neuronal optogenetics could become a future topic of technology assessment (TA).
Hans Zillmann
doaj   +1 more source

Thermal constraints on in vivo optogenetic manipulations. [PDF]

open access: yes, 2019
A key assumption of optogenetics is that light only affects opsin-expressing neurons. However, illumination invariably heats tissue, and many physiological processes are temperature-sensitive.
Kreitzer, Anatol C   +2 more
core  

Rodent models for the analysis of tissue clock function in metabolic rhythms research [PDF]

open access: yes, 2017
The circadian timing system consists on a distributed network of cellular clocks that together coordinate 24-h rhythms of physiology and behavior. Clock function and metabolism are tightly coupled, from the cellular to the organismal level.
Astiz, Mariana   +3 more
core   +2 more sources

Miniaturized Wireless tDCS With Concentric Electrodes for Targeted Cortical Stimulation in Freely Moving Mice

open access: yesAdvanced Healthcare Materials, EarlyView.
This study introduces a wireless and miniaturized concentric‐electrode tDCS (CE‐tDCS) system tailored for freely moving mice. The device enables focal and multi‐site cortical stimulation via a lightweight, Bluetooth‐controlled platform. By integrating local neuromodulation with real‐time behavioral analysis, the system provides a robust tool for ...
Minseok Kim   +5 more
wiley   +1 more source

Neurons and circuits for odor processing in the piriform cortex [PDF]

open access: yes, 2013
Increased understanding of the early stages of olfaction has lead to a renewed interest in the higher brain regions responsible for forming unified ‘odor images’ from the chemical components detected by the nose.
Bekkers, John MacDonald   +1 more
core   +1 more source

Machine learning-guided channelrhodopsin engineering enables minimally-invasive optogenetics

open access: yesNature Methods, 2019
We engineered light-gated channelrhodopsins (ChRs) whose current strength and light sensitivity enable minimally invasive neuronal circuit interrogation. Current ChR tools applied to the mammalian brain require intracranial surgery for transgene delivery
C. N. Bedbrook   +5 more
semanticscholar   +1 more source

UV Laser‐Induced Carbon Microelectrode Arrays for Neuronal Recordings

open access: yesAdvanced Healthcare Materials, EarlyView.
Thin‐film electrodes are flexible devices of high conformability and minimal dimensions with attractive properties for in vivo and in vitro bioelectronics. Here, electrodes are developed from parylene films via ultraviolet laser‐induced carbonization.
Fulvia Del Duca   +10 more
wiley   +1 more source

Optogenetics and Its Transformative Role in Tissue Engineering and Regenerative Medicine

open access: yesNano Select
Optogenetics, a revolutionary technique leveraging light stimulation for precise cellular control, holds immense potential in regenerative medicine. Offering unparalleled spatial and temporal accuracy, the entrance of optogenetics into tissue engineering
Emine Camcıoglu   +2 more
doaj   +1 more source

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