Results 111 to 120 of about 55,224 (387)
Photothermal neuromodulation is a promising technique for versatile neural signal study and treatment development. To further develop these technologies and optimize their effectiveness, transparent electrical temperature sensors with high thermal sensitivity and resolution are essential for accurately monitoring temperature changes during ...
Jee Woong Lee+7 more
wiley +1 more source
Calcium ion channels are involved in numerous biological functions such as lymphocyte activation, muscle contraction, neurotransmission, excitation, hormone secretion, gene expression, cell migration, memory, and aging.
Lena Maltan+3 more
doaj +1 more source
Distortion Distribution of Neural Spike Train Sequence Matching with Optogenetics [PDF]
This paper uses a simple optogenetic model to compare the timing distortion between a randomly-generated target spike sequence and an externally-stimulated neuron spike sequence. Optogenetics is an emerging field of neuroscience where neurons are genetically modified to express light-sensitive receptors that enable external control over when the ...
arxiv +1 more source
Significance Delivery of light for optogenetic stimulation of the brain is challenging, especially in small animals, because of behavioral constraints associated with physical tethering by fiber optic cables.
Jokubas Ausra+12 more
semanticscholar +1 more source
Optogenetic regulation of transcription [PDF]
Optogenetics has become widely recognized for its success in real-time control of brain neurons by utilizing non-mammalian photosensitive proteins to open or close membrane channels. Here we review a less well known type of optogenetic constructs that employs photosensitive proteins to transduce the signal to regulate gene transcription, and its ...
Olga Nazarenko+12 more
openaire +4 more sources
New Perspectives on Semiconducting Conjugated Oligomers for Neuromodulation in Hydra vulgaris
Semiconducting organic compounds, thiophene‐based, modify the rhythmic electrical activity of the cnidarian Hydra vulgaris acting on specific neuronal circuits. The ETE‐S trimer also forms electronically conducting wires in the living tissues of the animal.
Giuseppina Tommasini+7 more
wiley +1 more source
Colorless and translucent polyamide 4 (PA4) films, which are both bio‐based and biodegradable, were prepared by the solution casting method in a dual‐solvent system. The physical properties of single PA4 films were originally characterized, and the effects of molecular weight and environmental humidity on PA4 were investigated. Abstract The development
Di Zhang+6 more
wiley +1 more source
Illuminating pathogen-host intimacy through optogenetics.
The birth and subsequent evolution of optogenetics has resulted in an unprecedented advancement in our understanding of the brain. Its outstanding success does usher wider applications; however, the tool remains still largely relegated to neuroscience ...
Ruben Dario Arroyo-Olarte+3 more
doaj +1 more source
Bringing Optogenetics to the Synapse [PDF]
In this issue of Neuron, Lin et al. (2013) describe InSynC, an optogenetic approach that utilizes chromophore-assisted light inactivation (CALI) to inactivate presynaptic neurotransmitter release proteins VAMP2 and synaptophysin. InSynC selectively reduces synaptic transmission in illuminated regions in vitro and in vivo.
Ehud Y. Isacoff+5 more
openaire +3 more sources
Non-viral delivery and optimized optogenetic stimulation of retinal ganglion cells led to behavioral restoration of vision [PDF]
Stimulation of retinal neurons using optogenetics via use of chanelrhodopsin-2 (ChR2) has opened up a new direction for restoration of vision for treatment of retinitis pigmentosa (RP).
Edward Wong+5 more
core +2 more sources