Results 111 to 120 of about 43,018 (315)
An Open Resource for Non-human Primate Optogenetics [PDF]
Sébastien Tremblay +97 more
openalex +1 more source
Nurr1 Orchestrates Claustrum Development and Functionality
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan +12 more
wiley +1 more source
A Supervised STDP-based Training Algorithm for Living Neural Networks
Neural networks have shown great potential in many applications like speech recognition, drug discovery, image classification, and object detection.
Berdichevsky, Yevgeny +6 more
core +1 more source
Unlocking the potential of optogenetics in microbial applications
Moritz Benisch +2 more
openalex +1 more source
Optogenetic sensors and tools for studying brain signaling and neurodegenerative diseases [PDF]
Wenjing Wang
openalex +1 more source
Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins
As newly emerged optogenetic tools, potassium channelrhodopsins (KCRs) can drift from inhibition to activation during illumination as K⁺ selectivity declines. It is shown that both the absolute K⁺/Na⁺ permeability ratio and its stability over time govern this drift, identify KCR1‐C29D as a reliably inhibitory variant, and outline design principles for ...
Xiao Duan +14 more
wiley +1 more source
Optogenetic Vision Restoration Using Rhodopsin for Enhanced Sensitivity [PDF]
Benjamin M. Gaub +4 more
openalex +1 more source
Towards the clinical translation of optogenetic skeletal muscle stimulation [PDF]
Lili A. Gundelach +4 more
openalex +1 more source
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang +15 more
wiley +1 more source

