Results 111 to 120 of about 43,018 (315)

Optogenetic neuroregeneration

open access: yesNeural Regeneration Research, 2022
Janovjak, Harald, Kleinlogel, Sonja
openaire   +4 more sources

An Open Resource for Non-human Primate Optogenetics [PDF]

open access: bronze, 2020
Sébastien Tremblay   +97 more
openalex   +1 more source

Nurr1 Orchestrates Claustrum Development and Functionality

open access: yesAdvanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan   +12 more
wiley   +1 more source

A Supervised STDP-based Training Algorithm for Living Neural Networks

open access: yes, 2018
Neural networks have shown great potential in many applications like speech recognition, drug discovery, image classification, and object detection.
Berdichevsky, Yevgeny   +6 more
core   +1 more source

Unlocking the potential of optogenetics in microbial applications

open access: hybrid, 2023
Moritz Benisch   +2 more
openalex   +1 more source

Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins

open access: yesAdvanced Science, EarlyView.
As newly emerged optogenetic tools, potassium channelrhodopsins (KCRs) can drift from inhibition to activation during illumination as K⁺ selectivity declines. It is shown that both the absolute K⁺/Na⁺ permeability ratio and its stability over time govern this drift, identify KCR1‐C29D as a reliably inhibitory variant, and outline design principles for ...
Xiao Duan   +14 more
wiley   +1 more source

Optogenetic Vision Restoration Using Rhodopsin for Enhanced Sensitivity [PDF]

open access: bronze, 2015
Benjamin M. Gaub   +4 more
openalex   +1 more source

Towards the clinical translation of optogenetic skeletal muscle stimulation [PDF]

open access: hybrid, 2020
Lili A. Gundelach   +4 more
openalex   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

open access: yesAdvanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang   +15 more
wiley   +1 more source

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