Results 51 to 60 of about 84,774 (336)

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK pathways

Arthritis &Rheumatology, Accepted Article.
Introduction Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla, Maria Fresnadillo, Irene Sanchez‐Platero, Macarena de la Riva‐Bueno, Fernando Huete‐Toral, Gonzalo Carracedo, Carmen Conde, Yolanda Benitez, Pablo Minguez, Sandra Carolina Cifuentes, Joaquin Rams, Gabriel Herrero‐Beaumont, Raquel Largo, Aránzazu Mediero   +13 more
wiley   +1 more source

Public sector optometrists’ perspectives on a decentralised model of clinical training for optometry in KwaZulu-Natal, South Africa

African Vision and Eye Health, 2019
Background: Optometry training in KwaZulu-Natal has embraced a decentralised approach in keeping with other health professions. Decentralised clinical training enables health science students to gain clinical exposure at public hospitals during their ...
Nabeela Ebrahim, Fatima Karim, Mvelo Gasa, Kereshni Poonvaganum, Faaizah Gangat, Diane B. van Staden   +5 more
doaj   +1 more source

Studies of Vision in Cricket—A Narrative Review

Vision, 2023
Vision is thought to play a substantial role in hitting and fielding in cricket. An understanding of which visual skills contribute during cricket play could inform future clinical training trials.
Jennifer Swingle Fogt, Nick Fogt
doaj   +1 more source

The Accuracy of Accredited Glaucoma Optometrists in the Diagnosis and Treatment Recommendation for Glaucoma [PDF]

, 2007
Background/aims: To compare the diagnostic performance of accredited glaucoma optometrists (AGO) for both the diagnosis of, and decision to treat glaucoma with that of routine hospital eye care against a reference standard of expert opinion, i.e ...
Azuara-Blanco, Augusto, Burr, Jennifer Margaret, MacLennan, Graeme Stewart, McPherson, Stephen, Thomas, Ruth Elizabeth   +4 more
core   +3 more sources

Translation of a physiologically‐based pharmacokinetic model for dabigatran etexilate to the design of a safety and efficacy study in post‐partum women

British Journal of Clinical Pharmacology, EarlyView.
Aims To translate a PBPK model developed for the direct oral anticoagulant, dabigatran etexilate, the prodrug of dabigatran, based on data obtained from healthy men to healthy non‐pregnant, pregnant and post‐partum women. To evaluate safety and efficacy of dabigatran etexilate in post‐partum women using simulations and design a future clinical study to
Kayode Ogungbenro, Lorna Aucott, Farhad Kamali, Paul Ayuk   +3 more
wiley   +1 more source

Optometry student clinical practice at public health facilities: A systematic review

Health SA Gesondheid: Journal of Interdisciplinary Health Sciences
Background: Clinical training, supervision and practice are the most important aspects of health profession education, including optometry. Institutions implore various methods for students to gain access, exposure and experience in different clinical ...
Raserogole F. Segooa, Vanessa R. Moodley
doaj   +1 more source

Blue-light filtering spectacle lenses for visual performance, sleep, and macular health in adults [PDF]

, 2019
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess whether blue-light filtering spectacle lenses impart effects on visual function, provide protection to the macula, or both.
Busija, L., Downie, L. E., Hull, C., Keller, P. R., Lawrenson, J. G.   +4 more
core   +1 more source

Population pharmacokinetics and dose–response relationships of mitoxantrone in children with acute myeloid leukaemia

British Journal of Clinical Pharmacology, EarlyView.
Background Information on mitoxantrone pharmacokinetics in children is lacking and reduced dosing regimens applied to infants are supported by limited scientific rationale. The current study characterized mitoxantrone pharmacokinetics in a childhood acute myeloid leukaemia patient population and provides a data‐informed assessment of dosing.
Andrew M. Brandon, Hinke Huisman‐Siebinga, Shelby Barnett, Paul Wetherell, Pamela Kearns, Brenda Gibson, Nicholas Heaney, Owen Smith, André Baruchel, Arnaud Petit, Andrew Moore, Kayode Ogungbenro, Alwin D. R. Huitema, Gareth J. Veal   +13 more
wiley   +1 more source

Evaluating the Clinical Validity of Commercially Available Virtual Reality Headsets for Visual Field Testing: A Systematic Review

Vision
Virtual reality (VR) technology has emerged as a promising alternative to conventional perimetry for assessing visual fields. However, the clinical validity of commercially available VR-based perimetry devices remains uncertain due to variability in ...
Jesús Vera, Alan N. Glazier, Mark T. Dunbar, Douglas Ripkin, Masoud Nafey   +4 more
doaj   +1 more source

Freight-related greenhouse gas emissions in the supply of spectacle and contact lenses

African Vision and Eye Health, 2021
Background: Climate change is a global challenge requiring mitigation from all economic sectors. Although the consequences of climate change are well documented, there are limited studies regarding greenhouse gas emissions generated by the optometric ...
Rayishnee Pillay, Nishanee Rampersad, Rekha Hansraj   +2 more
doaj   +1 more source