Results 121 to 130 of about 7,612 (259)

Heat shock protein 72 attenuates atherosclerosis in apolipoprotein E‐deficient mice

Journal of Diabetes Investigation, EarlyView.
Heat shock (HS) + mild electrical stimulation (MES)‐induced heat shock protein (HSP)72 expression prevents atherogenesis in HSP72+/+/ApoE−/− mice. HS + MES‐induced HSP72 expression reduces macrophage infiltration, oxidative stress, JNK activity, and MCP‐1 expression, and alters macrophage polarity from M1 to M2.
Rintaro Yoshizumi, Tatsuya Kondo, Takuro Watanabe, Nobukazu Miyakawa, Sayaka Kitano, Mary Ann Suico, Miki Sato, Masaji Sakaguchi, Motoyuki Igata, Takeshi Matsumura, Hirofumi Kai, Eiichi Araki, Naoto Kubota   +12 more
wiley   +1 more source

When Large Language Models (LLMs) walk into a Bachelor's in optometry examination: Comparing the performances of LLMs and bachelor of optometry students. [PDF]

Indian J Ophthalmol
Arora A, Parmar UPS, Anjali, Mathur P, Kishore K, Singh U, Pandav SS, Gupta V.   +7 more
europepmc   +1 more source

Association between cardiometabolic risk factors cluster and all‐cause mortality in type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Objective To investigate the association between the cardiometabolic risk factors cluster (CRFC) and all‐cause mortality in type 2 diabetes (T2D). Methods Data from the Zhejiang Rural T2D Cohort (2016–2024) included 10,310 participants. Four cardiometabolic risk factors (CRFs) were evaluated: central obesity, elevated blood pressure, high ...
Qingfang He, Hongting Zhu, Yong Wang, Xiaoyan Zhou, Yuting Han, Ruying Hu   +5 more
wiley   +1 more source

Prevalence and severity of anxiety, depression, and stress among optometry students in Nigeria: A cross-sectional study. [PDF]

PLoS One
Kwarteng MA, Ogiemudia OM, Ekpenyong BN, Amaechi OU, Ogbonna G, Daniel-Nwosu EI, Ezinne NE, Ike OO, Ogbuechi KC, Osuagwu UL.   +9 more
europepmc   +1 more source

Evaluation of inadvertent stigmatization of individuals with diabetes by healthcare professionals

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction This study aimed to explore inadvertent stigmatizing attitudes of healthcare professionals (HCPs) toward people with diabetes (PWD) and to develop a questionnaire to assess such stigma. Materials and methods One hundred items that might reveal stigmatization of PWD were drafted in consultation with HCPs and previous reports ...
Nagaaki Tanaka, Yoshiyuki Hamamoto, Kiyohiro Izumi, Ryota Usui, Hitoshi Kuwata, Takanori Hyo, Masaki Yanase, Shinji Negoro, Hiroko Higashiyama, Yuichiro Yamada, Yutaka Seino   +10 more
wiley   +1 more source

Development of an entropy-weighted evaluation system for optometric education quality in vocational colleges of Yunnan Province. [PDF]

BMC Med Educ
Liu Z, Tao S, Yin H, Gu Z, Chen Y, Zhou J.   +5 more
europepmc   +1 more source

USP30 inhibits wound healing in diabetic foot ulcers by promoting TRAF6‐induced ferroptosis and angiogenesis inhibition

Journal of Diabetes Investigation, EarlyView.
High glucose upregulates USP30 in HUVECs, which deubiquitinates and stabilizes TRAF6. Stabilized TRAF6 suppresses GPX4 and SLC7A11, increases ROS/MDA/lipid peroxidation, and activates ferroptosis and apoptosis, leading to impaired angiogenesis and delayed wound healing.
Jingjing Yuan, Shuang Sui, Zhenghua Yang, Kaiwen Zhang, Qiang Hu   +4 more
wiley   +1 more source

The miR‐145‐5p/NRF2/SLC7A11 axis regulates ferroptosis‐mediated renal tubular epithelial cell injury in diabetic nephropathy

Journal of Diabetes Investigation, EarlyView.
Suppression of miR‐145‐5p alleviates DN‐associated renal tissue damage by inhibiting NRF2/SLC7A11‐mediated ferroptosis of RTECs. ABSTRACT Purpose This study aimed to investigate the molecular mechanism by which the miR‐145‐5p/NRF2/SLC7A11 axis regulates ferroptosis‐mediated renal tubular epithelial cell (RTEC) injury in diabetic nephropathy (DN ...
Ganlin Wu, Yu Fang, Meirong Xu, Zuopeng Lu, Yu Cao, Yana Gao   +5 more
wiley   +1 more source

Design and application of a web-based intelligent ophthalmic image analysis teaching platform. [PDF]

Front Med (Lausanne)
Chen J, Yang Y, Song Y, Huang Z, Li X, Qu B, Wan J, Zhong L.   +7 more
europepmc   +1 more source

Association of BCAAs/BCKAs with pancreatic steatosis in patients with type 2 diabetes mellitus: A cross‐sectional study

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims To examine the association between branched‐chain α‐keto acids (BCKAs) and pancreatic steatosis in patients with type 2 diabetes (T2DM). Methods This cross‐sectional study was conducted from January 2023 to March 2025. Upper abdominal computerized tomography was performed, pancreatic volume (PV), PV index (PVI), CT attenuation of pancreas
Jie Gao, Pijun Cheng, Fusong Jiang, Wenmin Li, Yingying Shi, Wenjun Wang, Liang Wang, Tao Lei, Yunxiang Zang, Jun Lu   +9 more
wiley   +1 more source