Results 131 to 140 of about 7,612 (259)

Targeting the miR‐224‐5p/PTEN pathway: A previously under‐characterized strategy to attenuate mesangial cell injury and predict prognosis in diabetic nephropathy

open access: yesJournal of Diabetes Investigation, EarlyView.
Serum miR‐224‐5p levels are progressively elevated in diabetic nephropathy (DN) and serve as an independent predictor of a decline in eGFR of ≥30% over 2 years. Mechanistically, miR‐224‐5p directly targets PTEN 3’‐UTR, suppressing PTEN and the activation of the AKT pathway in high‐glucose‐stimulated mesangial cells.
Yanxia Gao   +3 more
wiley   +1 more source

Artificial Intelligence in Optometry: Current and Future Perspectives

open access: yesClinical Optometry
Anantha Krishnan,1,* Ananya Dutta,2,* Alok Srivastava,3,4 Nagaraju Konda,1 Ruby Kala Prakasam5 1School of Medical Sciences, Science Complex, University of Hyderabad, Hyderabad, Telangana, India; 2Standard Chartered – LVPEI Academy for Eye Care ...
Krishnan A   +4 more
doaj  

Serum‐derived microribonucleic acids as potential novel biomarkers for slowly progressive type 1 diabetes mellitus

open access: yesJournal of Diabetes Investigation, EarlyView.
This study evaluated serum miRNAs as biomarkers in adult patients with SPIDDM. Serum miRNAs were measured at the time of SPIDDM (probable) diagnosis, and miR‐150‐5p was inversely associated with CPI at the last outpatient visit, suggesting its potential utility for predicting subsequent insulin secretory decline.
Hideyuki Okuma   +4 more
wiley   +1 more source

Clinical and psychological effects of the JADEC Diabetes Card System assessed using the Problem Areas in Diabetes (PAID): A retrospective observational study

open access: yesJournal of Diabetes Investigation, EarlyView.
A structured diabetes support program using a card‐based system was associated with reductions in diabetes‐related distress and improvements in glycemic control in real‐world clinical practice. These findings highlight the potential of shared‐care models to support patient‐centered diabetes management.
Yu Kouchi
wiley   +1 more source

Evaluation of a Collaborative Telehealth Model for Eye Care Between Ophthalmology and Optometry in Western Australia. [PDF]

open access: yesAust J Rural Health
Chen J   +6 more
europepmc   +1 more source

Alteration of subgingival microbiome in patients with type 2 diabetes induced by diabetes treatment

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction Diabetes and periodontal disease, a bacterial infection involving the oral microbiome, have a bidirectional relationship. However, the relationship between poor glycemic control and the oral microbiome remains unclear. The aim of this study was to assess the direct effect of intensive glycemic control on the oral microbiome ...
Moe Inoue   +13 more
wiley   +1 more source

Genetic basis of Asian diabetes

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Recent genomic studies in Asian populations have advanced our understanding of the diagnosis, pathophysiology, risk prediction, and precision care of diabetes. Monogenic diabetes, including maturity‐onset diabetes of the young (MODY) and mitochondrial diabetes, highlights the importance of genetic diagnosis for subtype‐specific care.
Takafumi Ojima, Toshimasa Yamauchi
wiley   +1 more source

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