Results 151 to 160 of about 8,117,567 (291)

Linagliptin increases the expression of LRP2 independent of Nrf2 in streptozotocin‐induced diabetic mice

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction Oxidative stress is thought to play a role in the onset and progression of diabetic nephropathy (DN). Nuclear factor erythroid‐related factor 2 (Nrf2) is a master regulator of antioxidant and detoxification pathways and provides cellular protection against oxidative stress.
Suratsawadee Promsuwan   +5 more
wiley   +1 more source

Fasting proinsulin as a predictor of future glucose tolerance deterioration in Japanese adults

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction Proinsulin is associated with β‐cell stress and has been linked to subsequent deterioration in glucose metabolism in Western populations, but its predictive value in Asian populations remains unclear. We investigated whether proinsulin is associated with future glucose tolerance deterioration in community‐dwelling Japanese ...
Nobuhiro Kajihara   +6 more
wiley   +1 more source

Kansas Board of Examiners in Optometry Newsletter, 2018

open access: yes, 2018
Newsletter issued annually This internet resource contains newsletter issued throughout several years. The Kansas State Board of Examiners in Optometry was established in 1909. Originally the three members of the Board were appointed by the Governor; in
Kansas. Board of Examiners in Optometry
core  

The cholesterol, high‐density lipoprotein, and glucose index and its derivatives related to obesity and inflammation as novel metabolic markers for predicting new‐onset cardiovascular‐liver‐metabolic multimorbidity: A prospective cohort study

open access: yesJournal of Diabetes Investigation, EarlyView.
The CHG index and its obesity‐derived variants were associated with incident CLMM, with CHG‐BMI showing the strongest association and predictive performance. CHG‐BMI may serve as a simple and accessible metabolic marker for CLMM risk stratification. ABSTRACT Background Cardiovascular‐liver‐metabolic multimorbidity (CLMM), defined as the co‐occurrence ...
Zhonghua Sun   +7 more
wiley   +1 more source

Myopia Awareness in Australia: Insights from a Nationwide Survey. [PDF]

open access: yesOphthalmic Physiol Opt
Vi M   +5 more
europepmc   +1 more source

LGR6 couples maresin 1 signaling to glycolytic flux and protein lactylation for the rescue of diabetic cardiomyopathy

open access: yesJournal of Diabetes Investigation, EarlyView.
MaR1 activates LGR6‐AMPK signaling to restore metabolic flexibility in diabetic hearts. Glycolytic recovery replenishes intracellular lactate to rescue protective protein lysine lactylation, which reactivates PINK1/Parkin‐mediated mitophagy to eliminate damaged mitochondria.
Bin Feng   +8 more
wiley   +1 more source

A Mixed-Methods Investigation of Myopia Management Practices Among Eye Care Practitioners in China. [PDF]

open access: yesOphthalmol Ther
Khew JM   +6 more
europepmc   +1 more source

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