Results 61 to 70 of about 1,810,829 (308)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Cost-minimization analysis of oral and intravenous administration of linezolid in a public hospital in southern Brazil

open access: yesRevista de Ciências Farmacêuticas Básica e Aplicada, 2015
Due to the paucity of cost-minimization studies about linezolid, the aim of this study was to estimate the cost differential between intravenous and oral administration.
Érika Taguti   +2 more
doaj  

Oral β-D-glucan potentiates systemic immune responses to intramuscular foot-and-mouth disease vaccination

open access: yesFrontiers in Veterinary Science
BackgroundFoot-and-mouth disease (FMD) is a viral disease primarily affecting livestock. Although vaccination is the main strategy to control FMD, current commercial FMD vaccines have major drawbacks, such as low antibody titers and short antibody titer ...
Hyeong Won Kim   +5 more
doaj   +1 more source

Different effects of oral and transdermal hormone replacement therapies on Factor IX, APC resistance, t-PA, PAI and C- reactive protein - a cross-sectional population survey [PDF]

open access: yes, 2001
The effects of hormone replacement therapy (HRT) on thrombosis risk, thrombotic variables, and the inflammatory marker C- reactive protein (CRP) may vary by route of administration (oral versus transdermal).
Lowe, G.D.O.   +5 more
core  

Finasteride adverse effects and post-finasteride syndrome; implications for dentists [PDF]

open access: yes, 2016
Finasteride is a 5α-reductase inhibitor widely used in present in the therapeutic approach of androgenic alopecia. Adverse effects consist in variable sign and symptoms, the most common being represented by mental troubles (reduced feeling of life ...
Dumitriu, Anca Silvia   +7 more
core   +4 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Trends of use and factors that determine the choice of oral anticoagulants in women and men with atrial fibrillation

open access: yesPharmacology Research & Perspectives, 2022
The aim was to identify sex‐specific factors linked with oral anticoagulant initiation in a cohort of patients with atrial fibrillation using administrative data from Quebec (Canada) between 2014 and 2017.
Aurélie Lenglet   +5 more
doaj   +1 more source

The polymeric stability of the Escherichia coli F4 (K88) fimbriae enhances its mucosal immunogenicity following oral immunization [PDF]

open access: yes, 2008
<p>Only a few vaccines are commercially available against intestinal infections since the induction of a protective intestinal immune response is difficult to achieve.
Cox, Eric   +9 more
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Ramsay Hunt syndrome a case report and review of literature [PDF]

open access: yes, 2013
This is a case report of a rather rare disorder i.e. Ramsay Hunt syndrome.  This is caused by Varicella zoster infections involving geniculate ganglion of facial nerve.  This syndrome is manifested by the presence of blebs in the external auditory canal,
Thiagarajan, Balasubramanian
core   +1 more source

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