Results 61 to 70 of about 1,538,497 (307)
The Mechanism of Action of Oral Anticoagulants and Its Consequences for the Practice of Oral Anticoagulation [PDF]
Haemostasis, 2009 A short review on the discovery of the relation between vitamin K and the synthesis of clotting factors and on the development of anticoagulant therapy is given. The pro-coagulant activity induced by vitamin K resides in the postribosomal modification of N-terminal glutamic acids in γ-COOH glutamic acids.
Hemker, H.C., Frank, H.L.L.
openaire +3 more sources
New oral anticoagulants in the prevention of stroke
, 2013 Atrial fibrillation is associated with a few folds higher risk of stroke. Traditional vitamin K antagonists used in the prevention of stroke in patients with non-valvular atrial fibrillation are often not efficient enough due to their interactions with a
Beata Wożakowska-Kapłon +2 more
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective We evaluated baseline characteristics, treatment patterns, and outcomes in patients with systemic autoimmune rheumatic disease–associated progressive pulmonary fibrosis (SARD‐PPF) and evaluated whether outcomes differed by SARD subtype. Methods The ILD‐PRO Registry is a prospective multicenter US registry of patients with PPF.
Sonali J. Bracken +7 more
wiley +1 more source
Travel and Oral Anticoagulants [PDF]
Journal of Travel Medicine, 2009 In their article Jurgen Ringwald and colleagues 1 do not take into account that in the United States there are only 50,000 international normalized ratio (INR) self‐testers out of 4 million people on warfarin (1.25%).2 In the United States, travel medicine providers should understand the ways in which warfarin is managed: usual care (UC) by the ...
openaire +2 more sources
British Journal of Clinical Pharmacology, EarlyView.Introduction Warfarin therapy is the mainstay of anticoagulation treatment in South Africa and requires frequent INR monitoring due to interindividual patient variability. Time in therapeutic range (TTR) reflects the proportion of total treatment time during which INR values are within therapeutic range.
Masudah Paleker +3 more
wiley +1 more source
JACC: Case Reports, 2020 Left ventricular (LV) thrombus in patients with reduced LV systolic function carries significant thromboembolic risk. Direct oral anticoagulants are an attractive alternative to warfarin for LV thrombus management.
Usman Ghani, MD +3 more
doaj +1 more source
Target-Specific Oral Anticoagulants—New Approaches in the Field of Oral Anticoagulation [PDF]
BioMed Research International, 2015 Direct oral anticoagulants targeting specific coagulation factors have been introduced as alternatives to conventional anticoagulants for both prophylactic and therapeutic indications. They have succeeded in overcoming the limitations of vitamin K antagonists.
Helen Mani +2 more
openaire +3 more sources
Laboratory monitoring of direct oral anticoagulants (DOACs)-The perfect storm?
, 2017 Laboratory monitoring of direct oral anticoagulants ...
LIPPI, Giuseppe, Favaloro, Emmanuel J.
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims To quantify prescribing adherence to renal dosing recommendations in adults with chronic kidney disease (CKD; Stage 3 and above) and to evaluate the clinical consequences of non‐adherence. Methods This systematic review and meta‐analysis was conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD42025620883).
Hager ElGeed +7 more
wiley +1 more source
BMC Gastroenterology, 2019 Background Heparin bridging therapy (HBT) is indeed related to a high frequency of bleeding after endoscopic mucosal resection (EMR). In this study, our aim was to investigate clinical impact of management of oral anticoagulants without HBT in bleeding ...
Shoko Ono +6 more
doaj +1 more source