Results 151 to 160 of about 261,112 (210)

mPEG-PCL Nanoparticles to Improve Oral Bioavailability of Acalabrutinib: Effect of Polymer Lipophilicity and Hydrophilicity on Physicochemical Properties and In Vivo Performance in Rats. [PDF]

Pharmaceutics
Sinha S, Ravi PR, Rashmi SR, Szeleszczuk Ł.   +3 more
europepmc   +1 more source

Enhancement of oral bioavailability of ibrutinib using a liposil nanohybrid delivery system. [PDF]

PLoS One
Ashar F, Mohammed AAS, Selvamuthukumar S.   +2 more
europepmc   +1 more source

Microcontainers improve oral bioavailability of furosemide [PDF]

, 2015
Boisen, Anja, Keller, Stephan Sylvest, Melero, A., Müllertz, A., Nielsen, Line Hagner, Rades, T.   +5 more
core   +1 more source

Selection of In Vivo Relevant Dissolution Test Parameters for the Development of Cannabidiol Formulations with Enhanced Oral Bioavailability. [PDF]

Pharmaceutics
Koch N, Bourcy Q, Jennotte O, Chiap P, Lechanteur A, Cardot JM, Evrard B.   +6 more
europepmc   +1 more source

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Bioavailability of oral dexamethasone

Clinical Pharmacology & Therapeutics, 1975
Bioavailabilities of dexamethasone tablets and elixir in man were evaluated by each of 3 model‐independent methods of pharmacokinetic analysis employing plasma and urinary values as determined by radioimmune assay. There were no significant differences among the results determined by the 3 methods nor between the respective availabilities of the !Wo ...
D E, Duggan, K C, Yeh, N, Matalia, C A, Ditzler, F G, McMahon   +4 more
openaire   +2 more sources

The Bioavailability of Oral Nitroglycerin

Journal of Pharmaceutical Sciences, 1986
In the 1970's, the efficacy of oral nitroglycerin therapy was seriously challenged, primarily on the basis of animal studies showing complete first-pass hepatic metabolism of nitroglycerin. Today, it is generally accepted that high oral doses of nitroglycerin do show antianginal efficacy. It has been suggested that this efficacy results from saturation
P K, Noonan, L Z, Benet
openaire   +2 more sources

Bioavailability of oral micronized progesterone

Fertility and Sterility, 1985
Progesterone (P) has not been administered orally because of reportedly poor bioavailability and a rapid clearance rate. Unfortunately, the synthetic derivatives, although orally active, have a number of disadvantages and fail to mimic natural P completely.
W S, Maxson, J T, Hargrove
openaire   +2 more sources

The Absolute Bioavailability of Oral Melatonin

The Journal of Clinical Pharmacology, 2000
The absolute bioavailability of oral melatonin tablets was studied in 12 normal healthy volunteers. Subjects were administered, in a randomized crossover fashion, melatonin 2 mg intravenously and 2 and 4 mg orally. Blood was sampled over approximately eight (estimated) half‐lives.
R L, DeMuro, A N, Nafziger, D E, Blask, A M, Menhinick, J S, Bertino   +4 more
openaire   +2 more sources

Oral Bioavailability

2010
Soil ingestion is a key exposure pathway in Human Health Risk Assessment for contaminants in soil. The theory and mechanisms of how contaminants in a soil enter the human body through the gastrointestinal tract are outlined. The methods available for measuring human exposure using human, animal and validated in-vitro laboratory methods are described ...
Cave, Mark, Wragg, Joanna, Denys, Sébastien, Jondreville, Catherine, Feidt, Cyril   +4 more
openaire   +3 more sources