Results 21 to 30 of about 4,901,377 (308)

7-Epitaxol Induces Apoptosis and Autophagy in Head and Neck Squamous Cell Carcinoma through Inhibition of the ERK Pathway

Cells, 2021
As the main derivative of paclitaxel, 7-Epitaxol is known to a have higher stability and cytotoxicity. However, the anticancer effect of 7-Epitaxol is still unclear.
V. Bharath Kumar, Ming-Ju Hsieh, B. Mahalakshmi, Yi-Ching Chuang, Chia-Chieh Lin, Yu-Sheng Lo, Hsin-Yu Ho, Jen-Tsun Lin   +7 more
doaj   +1 more source

Snail reprograms glucose metabolism by repressing phosphofructokinase PFKP allowing cancer cell survival under metabolic stress

Nature Communications, 2017
Cancer cell survival under metabolic stress is a critical step for metastasis. Here, the authors show that under glucose deprivation, Snail, a key regulator of the metastatic process, promotes survival by diverting glucose to the pentose phosphate ...
Nam Hee Kim, Yong Hoon Cha, Jueun Lee, Seon-Hyeong Lee, Ji Hye Yang, Jun Seop Yun, Eunae Sandra Cho, Xianglan Zhang, Miso Nam, Nami Kim, Young-Su Yuk, So Young Cha, Yoonmi Lee, Joo Kyung Ryu, Sunghyouk Park, Jae-Ho Cheong, Sang Won Kang, Soo-Youl Kim, Geum-Sook Hwang, Jong In Yook, Hyun Sil Kim   +20 more
doaj   +1 more source

Oral microbiota and oral cancer: Review

Oncology Reviews, 2020
In this review, we draw attention and discuss the risk factors and causes of the development of oral squamous cell carcinoma (OSCC) focusing on oral microbiota. Recently, a breakthrough in the study of cancer has been the discovery of the relationship between the presence of certain types of bacteria and the development of cancer in the human body ...
Mariam Z. Kakabadze, Teona Paresishvili, Lia Karalashvili, David Chakhunashvili, Zurab Kakabadze   +4 more
openaire   +4 more sources

Targeting transcription of MCL-1 sensitizes HER2-amplified breast cancers to HER2 inhibitors

Cell Death and Disease, 2021
Human epidermal growth factor receptor 2 gene (HER2) is focally amplified in approximately 20% of breast cancers. HER2 inhibitors alone are not effective, and sensitizing agents will be necessary to move away from a reliance on heavily toxic ...
Konstantinos V. Floros, Sheeba Jacob, Richard Kurupi, Carter K. Fairchild, Bin Hu, Madhavi Puchalapalli, Jennifer E. Koblinski, Mikhail G. Dozmorov, Sosipatros A. Boikos, Maurizio Scaltriti, Anthony C. Faber   +10 more
doaj   +1 more source

Interventions for the treatment of oral cavity and oropharyngeal cancer: chemotherapy. [PDF]

, 2010
Oral cavity and oropharyngeal cancers are frequently described as part of a group of oral cancers or head and neck cancer. Treatment of oral cavity cancer is generally surgery followed by radiotherapy, whereas oropharyngeal cancers, which are more likely
Clarkson, Jan E.; id_orcid, null The CSROC Expert Panel, Furness, Susan, Glenny, A.M., Oliver, R., Jan E Clarkson, Macluskey, Michaelina; id_orcid, Furness, S, Glenny, Anne-Marie, Macluskey, M., Clarkson, Jan E., The CSROC Expert Panel, CSROC Expert Panel, Chan, Kelvin K.W., Chan, K.K.W., Conway, DI, Clarkson, Jan E, Conway, David I., Glenny, AM, Clarkson, JE, Kelvin KW Chan, Pavitt, S., Worthington, Helen V, CSROC Expert Panel, [Unknown], Michaelina Macluskey, Furness, S., Worthington, Helen V., The CSROC Expert Panel,, Chan, Kelvin K. W., Pavitt, S, Chan, Kelvin KW, Anne-Marie Glenny, Oliver, R, Glenny, Anne Marie; id_orcid, David I Conway, Conway, D.I., Macluskey, Michaelina, Worthington, HV; id_orcid, Clarkson, J.E., Pavitt, Sue, Chan, KK, Worthington, HV, Macluskey, M, Worthington, Helen V.; id_orcid, Richard Oliver, Oliver, Richard, Helen V Worthington, Susan Furness, Sue Pavitt, Paul Brocklehurst, Worthington, H.V., Brocklehurst, Paul, Brocklehurst, P   +52 more
core   +1 more source

Elective neck dissection versus wait-and-see policy in cT1N0 buccal squamous cell carcinoma

BMC Cancer, 2020
Background Our goal was to clarify the comparison between elective neck dissection (END) and the wait-and-see policy in neck management for cT1N0 buccal squamous cell carcinoma (SCC).
Qigen Fang, Hua Gao, Qing Gao, Jinlan Sun, Peng Li, Meng Cui, Enxi Zhang, Wenlong Yin, Yuanyuan Dong   +8 more
doaj   +1 more source

Surgical management and final outcomes of chondrosarcoma of the temporomandibular joint: case series and comprehensive literature review

World Journal of Surgical Oncology, 2023
Background Surgical management for chondrosarcoma of the temporomandibular joint (TMJ) is challenging due to the anatomical location involving the facial nerve and the functional joint. The purpose of this case series was to analyze the largest number of
Hyun Jun Oh, Hye-Jung Yoon, Kyung-Hoe Huh, Bongju Kim, Ik-Jae Kwon, Soung Min Kim, Joo Yong Park, Sung Weon Choi, Jong-Ho Lee   +8 more
doaj   +1 more source

A Comprehensive Review of Natural Products as Therapeutic or Chemopreventive Agents against Head and Neck Squamous Cell Carcinoma Cells Using Preclinical Models

Biomedicines, 2023
Head and neck squamous cell carcinoma (HNSCC) is a type of cancer that arises from the epithelium lining of the oral cavity, hypopharynx, oropharynx, and larynx.
Yoon Xuan Liew, Lee Peng Karen-Ng, Vui King Vincent-Chong   +2 more
doaj   +1 more source

Pentapartite fractionation of particles in oral fluids by differential centrifugation

Scientific Reports, 2021
Oral fluids (OFs) contain small extracellular vesicles (sEVs or exosomes) that carry disease-associated diagnostic molecules. However, cells generate extracellular vesicles (EVs) other than sEVs, so the EV population is quite heterogeneous.
Chiho Hiraga, Satoshi Yamamoto, Sadamitsu Hashimoto, Masataka Kasahara, Tamiko Minamisawa, Sachiko Matsumura, Akira Katakura, Yasutomo Yajima, Takeshi Nomura, Kiyotaka Shiba   +9 more
doaj   +1 more source

Oral cancer in Taiwan: is diabetes a risk factor?

, 2014
The association between diabetes and oral cancer is rarely studied. We investigated the trends of oral cancer in the Taiwanese general population and the possible link with diabetes.
Tseng, Chin-Hsiao, 曾慶孝
core   +1 more source