Results 41 to 50 of about 4,901,377 (308)

The Oral Examination, Oral Cancer and Pre-Cancer

MedEdPORTAL, 2013
Abstract The oral cavity is a key anatomic location. Yet in the course of professional training of physicians, dentists, and other health professionals, it is often given only modest attention. This module emphasizes the importance of the oral examination as a component of the general physical examination, and its role in the routine screening for oral
Easwar Natarajan, Ellen Eisenberg, Miranda Jennings   +2 more
openaire   +2 more sources

Oral and pharyngeal cancer in South Asians and non-South Asians in relation to socioeconomic deprivation in South East England. [PDF]

, 2008
From UK Thames Cancer Registry data, after controlling for socioeconomic deprivation of area of residence, South Asian males showed a higher relative risk of oral (1.36; 95% CI: 1.11, 1.67), but not of pharyngeal cancer than non-South Asian males ...
Moles, DR, Silva, I.D., Silva, IDS, Speight, P.M., Fedele, S., Porter, S.R., Moles, D.R., dos Santos Silva, I, P M Speight, Porter, SR, Fedele, S, Speight, PM, D R Moles, S R Porter, I dos Santos Silva, S Fedele   +15 more
core   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Assembly and activation of the Hippo signalome by FAT1 tumor suppressor

Nature Communications, 2018
Dysregulation of the Hippo signaling is a frequent event in human malignancies, but the molecular mechanisms remain unclear. Here the authors show that in head and neck squamous carcinoma, FAT1 interacts with the Hippo signaling complex, resulting in the
Daniel Martin, Maria S. Degese, Lynn Vitale-Cross, Ramiro Iglesias-Bartolome, Juan Luis Callejas Valera, Zhiyong Wang, Xiaodong Feng, Huwate Yeerna, Vachan Vadmal, Toshiro Moroishi, Rick F. Thorne, Moraima Zaida, Bradford Siegele, Sok C. Cheong, Alfredo A. Molinolo, Yardena Samuels, Pablo Tamayo, Kun Liang Guan, Scott M. Lippman, J. Guy Lyons, J. Silvio Gutkind   +20 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Analysis of the outcome of young age tongue squamous cell carcinoma

Maxillofacial Plastic and Reconstructive Surgery, 2017
Background The incidence of tongue squamous cell carcinoma (TSCC) in young patients has recently increased, and these TSCCs are believed to be etiologically distinct from those in older patients, who have longer exposure to risk factors such as tobacco ...
Jae-Ho Jeon, Min Gyun Kim, Joo Yong Park, Jong Ho Lee, Myung Jin Kim, Hoon Myoung, Sung Weon Choi   +6 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The mRNA profile of genes in betel quid chewing oral cancer patients.

, 2009
Oral cancer is one of the most common types of human cancer in the world. Although the risk factors for oral cancer are well-recognized in different countries, the molecular mechanism responsible for this malignancy remains elusive particularly in the ...
柯政郁, TSAI, WAN-CHI;TSAI, SEN-TIEN;KO, JENQ-YUH;JIN, YING-TAI;LI, CHING;HUANG, WENYA;YOUNG, KUNG-CHIA;LAI, MING-DER;LIU, HSIAO-SHENG;WU, LI-WHA   +1 more
core   +1 more source

Screening programmes for the early detection and prevention of oral cancer [PDF]

, 2010
Background Oral cancer is an important global healthcare problem, its incidence is increasing and late-stage presentation is common. Screening programmes have been introduced for a number of major cancers and have proved effective in their early ...
Richard Oliver, Oliver, Richard, Sloan, Philip, Omar Kujan, Ogden, Graham; id_orcid, Graham Ogden, Anne-Marie Glenny, Paul Brocklehurst, Kujan, Omar, Simon Shepherd, Brocklehurst, Paul, Glenny, Anne-Marie, Philip Sloan, Shepherd, Simon   +13 more
core   +1 more source