Results 51 to 60 of about 1,238,683 (306)
Dishevelled has a YAP nuclear export function in a tumor suppressor context-dependent manner
Nature Communications, 2018 Hippo and Wnt pathways are important for cancer development, and they can cross talk; however, the mechanisms behind this connection are unknown. Here the authors show that DVL (a scaffold protein in the Wnt pathway) regulates the shuttling of YAP (a key
Yoonmi Lee +17 more
doaj +1 more source
ABC of oral health: Oral cancer [PDF]
BMJ, 2000 Most mouth cancer is oral squamous cell carcinoma. This is uncommon in the developed world, except in parts of France, but is common in the developing world, particularly South East Asia and Brazil. It is mainly seen in men over middle age (though it is increasing in younger people), tobacco users, and lower socioeconomic groups.
C, Scully, S, Porter
openaire +2 more sources
Durable response using regorafenib in an elderly patient with metastatic colorectal cancer: case report. [PDF]
, 2015 Regorafenib, an oral multikinase inhibitor, was approved in September 2012 by the US Food and Drug Administration for the treatment of patients with metastatic colorectal cancer.
Herman, June +3 more
core +3 more sources
Limocitrin induced cellular death through ERK pathways in human oral squamous cell cancer
Scientific ReportsThis study sought to investigate the anticancer efficacy of limocitrin on two distinct human oral cancer cell lines. At first, we evaluated the effect of limocitrin on the proliferation of OSCC cells (SCC-9 and SCC-47) using MTT and colony formation ...
Bharath Kumar Velmurugan +6 more
doaj +1 more source
Clinical Insights Into Hypercalcemia of Malignancy in Childhood
Pediatric Blood &Cancer, EarlyView.ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley +1 more source
Oral microbiota and oral cancer: Review
Oncology Reviews, 2020 In this review, we draw attention and discuss the risk factors and causes of the development of oral squamous cell carcinoma (OSCC) focusing on oral microbiota. Recently, a breakthrough in the study of cancer has been the discovery of the relationship between the presence of certain types of bacteria and the development of cancer in the human body ...
Mariam Z. Kakabadze +4 more
openaire +4 more sources
Oral cancer in the UK: to screen or not to screen. [PDF]
, 1998 Although oral squamous cell carcinoma accounts for only a small proportion of malignant neoplasms in the UK, oral cancer incidence and mortality rates have been rising in recent years.
Rodrigues, Veena
core
Print and online newspaper coverage of the link between HPV and oral cancer in the UK: a mixed-methods study [PDF]
, 2016 OBJECTIVES: The role of human papillomavirus (HPV) in some oral cancers has been reported in the news press, though little is known about the content of these articles.
Dodd, RH +3 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman +8 more
wiley +1 more source