Cells, 2021 As the main derivative of paclitaxel, 7-Epitaxol is known to a have higher stability and cytotoxicity. However, the anticancer effect of 7-Epitaxol is still unclear.
V. Bharath Kumar +7 more
doaj +1 more source
Metabolomic analysis of human oral cancer cells with adenylate kinase 2 or phosphorylate glycerol kinase 1 inhibition. [PDF]
, 2017 The purpose of this study was to use liquid chromatography-mass spectrometry (LC-MS) with XCMS for a quantitative metabolomic analysis of UM1 and UM2 oral cancer cells after knockdown of metabolic enzyme adenylate kinase 2 (AK2) or phosphorylate glycerol
Cheng, Siliangyu +6 more
core +1 more source
Oral tolerance to cancer can be abrogated by T regulatory cell inhibition [PDF]
, 2014 Oral administration of tumour cells induces an immune hypo-responsiveness known as oral tolerance. We have previously shown that oral tolerance to a cancer is tumour antigen specific, non-cross-reactive and confers a tumour growth advantage.
A Micheli +27 more
core +4 more sources
Oral cancer secretome: Identification of cancer-associated proteins [PDF]
, 2014 This study aims to identify cancer-associated proteins in the secretome of oral cancer cell lines. We have successfully established four primary cell cultures of normal cells with a limited lifespan without human telomerase reverse transcriptase (hTERT ...
Chang, H. Y. +6 more
core +1 more source
Nature Communications, 2017 Cancer cell survival under metabolic stress is a critical step for metastasis. Here, the authors show that under glucose deprivation, Snail, a key regulator of the metastatic process, promotes survival by diverting glucose to the pentose phosphate ...
Nam Hee Kim +20 more
doaj +1 more source
Targeting transcription of MCL-1 sensitizes HER2-amplified breast cancers to HER2 inhibitors
Cell Death and Disease, 2021 Human epidermal growth factor receptor 2 gene (HER2) is focally amplified in approximately 20% of breast cancers. HER2 inhibitors alone are not effective, and sensitizing agents will be necessary to move away from a reliance on heavily toxic ...
Konstantinos V. Floros +10 more
doaj +1 more source
Interventions for treating oral mucositis for patients with cancer receiving treatment [PDF]
, 2010 Background Treatment of cancer is increasingly effective but is associated with short and long term side effects. Oral and gastrointestinal side effects, including oral candidiasis, remain a major source of illness despite the use of a variety of agents ...
Clarkson, Jan E. +5 more
core +8 more sources
The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer. [PDF]
, 2016 A better understanding of the dynamics of molecular changes occurring during the early stages of oral tumorigenesis may help refine prevention and treatment strategies.
Bertolus, Chloé +14 more
core +1 more source
Elective neck dissection versus wait-and-see policy in cT1N0 buccal squamous cell carcinoma
BMC Cancer, 2020 Background Our goal was to clarify the comparison between elective neck dissection (END) and the wait-and-see policy in neck management for cT1N0 buccal squamous cell carcinoma (SCC).
Qigen Fang +8 more
doaj +1 more source
Systematic Review of Laser and Other Light Therapy for the Management of Oral Mucositis in Cancer Patients [PDF]
, 2012 Background The aim of this study was to review the available literature and define clinical practice guidelines for the use of laser and other light therapies for the prevention and treatment of oral mucositis.
Brian Hodgson +10 more
core +2 more sources