Results 81 to 90 of about 601,354 (269)

Induction of Nephron–Ductal Dual Lineages via Early Retinoic Acid Signaling Establishes a Platform for Fully Patterned Kidney Organoids

Advanced Healthcare Materials, EarlyView.
A simplified, co‐culture‐free protocol for kidney organoids that generate segmented nephrons, including collecting ducts, has been developed. Early low‐dose RA with FGF9 induces balanced anterior–posterior IM patterning and dual UE/MM lineage commitment. BMP7 enhances nephron progenitor maturation.
Jung Hwa Lim, Seeun Kim, Dong Hyun Lee, Dae Hun Kim, Hye Bin Lee, Ye Seul Son, Mi‐Young Son, Soo Jin Oh, Ji‐Yoon Lee, Mi‐Ok Lee, Hyun Soo Cho, Dae‐Soo Kim, Cho‐Rok Jung, Hyun Mi Kang   +13 more
wiley   +1 more source

Net Clinical Benefit of Direct Oral Anticoagulants in Patients With Cancer and Venous Thromboembolism: A Systematic Review and Trade-Off Analysis

, 2020
Yi‐Dan Yan, Zheng Ding, Mang-Mang Pan, Qing Xia, Jiujie Cui, Liwei Wang, Chi Zhang, Zhi‐Chun Gu   +7 more
openalex   +1 more source

circRNA_100290 plays a role in oral cancer by functioning as a sponge of the miR-29 family [PDF]

, 2017
L. Chen, Shuangyang Zhang, Jingwen Wu, Jian Cui, Liang Zhong, Ling Zeng, Shengfang Ge   +6 more
openalex   +1 more source

An Innovative “Tooth‐On‐Chip” Microfluidic Device Emulating the Structure and Physiology of the Dental Pulp Tissue

Advanced Healthcare Materials, EarlyView.
This work presents a “tooth‐on‐chip” device that mimics dental pulp tissue. By co‐culturing key cell types, it recreates vascular networks, stem cell niches, the odontoblast/dentine interface, and trigeminal innervation. This innovative platform provides a unique model of dental pulp structure and physiology, with significant potential for accelerating
Alessandro Cordiale, Deborah Stanco, Roberta Visone, Bernd Stadlinger, Pierfrancesco Pagella, Marco Rasponi, Thimios A. Mitsiadis   +6 more
wiley   +1 more source

Prevalence of tobacco and areca-nut use among patients attending dental teaching hospital in the central province of Sri Lanka and its association with oral mucosal lesions; a cross sectional study

Journal of Oral Biology and Craniofacial Research
Introduction: Tobacco and areca-nut are risk factors for oral cancer and potentially malignant disorders. Oral cancer is ranked as the commonest among males in Sri Lanka (18.4 %).
Sumali Sumithrarachchi, Isuru Athukorala, Fazly Rumy, Ruwan Jayasinghe   +3 more
doaj   +1 more source

Expression and regulation of long noncoding RNAs during the osteogenic differentiation of periodontal ligament stem cells in the inflammatory microenvironment

Scientific Reports, 2017
Although long noncoding RNAs (lncRNAs) have been emerging as critical regulators in various tissues and biological processes, little is known about their expression and regulation during the osteogenic differentiation of periodontal ligament stem cells ...
Qingbin Zhang, Li Chen, Shiman Cui, Yan Li, Qi Zhao, Wei Cao, Shixiang Lai, Sanjun Yin, Zhixiang Zuo, Jian Ren   +9 more
doaj   +1 more source

Discovery and Evaluation of 3-Quinoxalin Urea Derivatives as Potent, Selective, and Orally Available ATM Inhibitors Combined with Chemotherapy for the Treatment of Cancer via Goal-Oriented Molecule Generation and Virtual Screening

, 2023
Dexin Deng, Yingxue Yang, Yurong Zou, Kongjun Liu, Chufeng Zhang, Minghai Tang, Tao Yang, Yong Chen, Yuan Xue, Yong Guo, Shunjie Zhang, Wenting Si, Bin Peng, Qing Xu, Wen He, Dingguo Xu, Mingli Xiang, Lijuan Chen   +17 more
openalex   +1 more source

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source

p53‐independent Noxa induction by cisplatin is regulated by ATF3/ATF4 in head and neck squamous cell carcinoma cells

Molecular Oncology, 2018
The platinum‐based DNA damaging agent cisplatin is used as a standard therapy for locally advanced head and neck squamous cell carcinoma (HNSCC). However, the mechanisms underpinning the cytotoxic effects of this compound are not entirely elucidated ...
Kanika Sharma, Thien‐Trang Vu, Wade Cook, Mitra Naseri, Kevin Zhan, Wataru Nakajima, Hisashi Harada   +6 more
doaj   +1 more source

Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk

Advanced Healthcare Materials, EarlyView.
Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor, Giuseppe Longobardi, Or Kandli, Anne Krinsky, Opal Avramoff, Anshika Katyal, Koren Salomon, Adan Miari, Dana Venkert, Tania T. Barnatan, América García Alvarado, Shahar Greenberg, Ronit Satchi‐Fainaro   +12 more
wiley   +1 more source