Results 91 to 100 of about 9,597 (210)

Anti-O-specific polysaccharide (OSP) immune responses following vaccination with oral cholera vaccine CVD 103-HgR correlate with protection against cholera after infection with wild-type Vibrio cholerae O1 El Tor Inaba in North American volunteers.

PLoS Neglected Tropical Diseases, 2018
BackgroundCholera is an acute voluminous dehydrating diarrheal disease caused by toxigenic strains of Vibrio cholerae O1 and occasionally O139. A growing body of evidence indicates that immune responses targeting the O-specific polysaccharide (OSP) of V.
Kamrul Islam, Motaher Hossain, Meagan Kelly, Leslie M Mayo Smith, Richelle C Charles, Taufiqur Rahman Bhuiyan, Pavol Kováč, Peng Xu, Regina C LaRocque, Stephen B Calderwood, Jakub K Simon, Wilbur H Chen, Douglas Haney, Michael Lock, Caroline E Lyon, Beth D Kirkpatrick, Mitchell Cohen, Myron M Levine, Marc Gurwith, Jason B Harris, Firdausi Qadri, Edward T Ryan   +21 more
doaj   +1 more source

Use of oral cholera vaccines in an outbreak in Vietnam: a case control study. [PDF]

PLoS Neglected Tropical Diseases, 2011
BACKGROUND: Killed oral cholera vaccines (OCVs) are available but not used routinely for cholera control except in Vietnam, which produces its own vaccine.
Dang Duc Anh, Anna Lena Lopez, Vu Dinh Thiem, Shannon L Grahek, Tran Nhu Duong, Jin Kyung Park, Hye Jung Kwon, Michael Favorov, Nguyen Tran Hien, John D Clemens   +9 more
doaj   +1 more source

Novel applications of the tomato microbiome: Roles and considerations for agriculture, human health, and society

PLANTS, PEOPLE, PLANET, Volume 8, Issue 2, Page 530-555, March 2026.
Plants, like humans, have a microbiome that helps them grow, defend themselves against pathogens, acquire nutrients, and protect themselves against environmental stresses. The microbiome of tomatoes, a staple crop grown worldwide, could be utilized not only to reduce fertilizer and pesticide applications, but also to clean up harmful pollutants ...
Sean Lindert, Kathryn Kingsley, Peerapol Chiaranunt, James F. White   +3 more
wiley   +1 more source

Development of DuoChol, a Thermostable Inactivated Whole-Cell/B-Subunit Oral Cholera Vaccine in Enteric Capsule

Vaccines
Background/Objectives: Cholera remains an important global health problem. Inactivated oral cholera vaccines (OCVs) are essential in the WHO/GTFCC (World Health Organization/Global Task Force on Cholera Control) strategy to end cholera by 2030; however ...
Manuela Terrinoni, Michael R. Lebens, Stefan L. Nordqvist, Frida Nilsson, Madeleine Löfstrand, Julia Lynch, Jan Holmgren   +6 more
doaj   +1 more source

A Recombinant Live Oral Cholera Vaccine [PDF]

Nature Biotechnology, 1984
A pathogenic strain of Vibrio cholerae was attenuated by deletion of DNA sequences encoding the A1 subunit of the cholera enterotoxin. A restriction endonuclease fragment encoding the A1, but not the A2 or B sequences was deleted in vitro from cloned cholera toxin genes.
James B. Kaper, Hank Lockman, Mary M. Baldini, Myron M. Levine   +3 more
openaire   +1 more source

The impact and cost-effectiveness of controlling cholera through the use of oral cholera vaccines in urban Bangladesh: A disease modeling and economic analysis. [PDF]

PLoS Neglected Tropical Diseases, 2018
BACKGROUND:Cholera remains an important public health problem in major cities in Bangladesh, especially in slum areas. In response to growing interest among local policymakers to control this disease, this study estimated the impact and cost ...
Ashraful Islam Khan, Ann Levin, Dennis L Chao, Denise DeRoeck, Dobromir T Dimitrov, Jahangir A M Khan, Muhammad Shariful Islam, Mohammad Ali, Md Taufiqul Islam, Abdur Razzaque Sarker, John D Clemens, Firdausi Qadri   +11 more
doaj   +1 more source

Vaccine Candidates Designed to Prevent Enterotoxigenic Escherichia coli Diarrhoea: A Scoping Review of Clinical Trials Evaluating Vaccine Candidates in Development

Tropical Medicine &International Health, Volume 31, Issue 3, Page 295-306, March 2026.
ABSTRACT Objectives The primary objectives of this study are to (1) summarise the current landscape of ETEC vaccine development by describing, characterising and comparing ETEC vaccine candidates in clinical development, (2) assess key characteristics of the phases 1, 2 and 3 clinical trials that have been designed to evaluate ETEC vaccines in ...
Vaidehi Nafade, Naheemot O. Sule, Yang Zhang, Angelina Sassi, Nicole E. Basta   +4 more
wiley   +1 more source

Developing downstream processes for the purification of recombinant proteins and small molecules from Nicotiana benthamiana biomass

Plant Biotechnology Journal, Volume 24, Issue 1, Page 66-80, January 2026.
Summary Nicotiana benthamiana (Australian tobacco) has become a major host for plant‐based recombinant protein production, especially using transient expression. Once a candidate protein has been designed and produced in a suitable variety (e.g. facilitated humanized glycosylation) under reproducible conditions (e.g.
J. F. Buyel
wiley   +1 more source

History of the development of oral cholera vaccine in Vietnam. [PDF]

, 2014
History of the development of oral cholera vaccine in Vietnam.
Dang Duc Anh (232106), Jacqueline L. Deen (148731), Anna Lena Lopez (92298), Vu Dinh Thiem (232108), Hung Thi Mai Tran (624674), Nguyen Van Cuong (624675), Lorenz von Seidlein (45473), David A. Sack (219219), Mohammad Ali (73095)   +8 more
core   +1 more source

Controlling cholera in the Ouest Department of Haiti using oral vaccines.

PLoS Neglected Tropical Diseases, 2017
Following the 2010 cholera outbreak in Haiti, a plan was initiated to provide massive improvements to the sanitation and drinking water infrastructure in order to eliminate cholera from the island of Hispaniola by 2023.
Alexander Kirpich, Thomas A Weppelmann, Yang Yang, John Glenn Morris, Ira M Longini   +4 more
doaj   +1 more source