Results 71 to 80 of about 9,597 (210)

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, Volume 6, Issue 4, April 2026.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

The case for ring vaccinations with special consideration of oral cholera vaccines [PDF]

Human Vaccines & Immunotherapeutics, 2018
Ring vaccinations create a zone of immune contacts around a case to prevent further disease transmission and have been successfully employed in the eradication of smallpox and the control of other infections. Millions of oral cholera vaccine (OCV) doses have been effectively deployed through mass vaccination campaigns. But there are situations when the
Deen, J, Von Seidlein, L
openaire   +4 more sources

Bivalent oral cholera vaccination induces a memory B cell response to the V. cholerae O1-polysaccharide antigen in Haitian adults.

PLoS Neglected Tropical Diseases, 2019
The bivalent killed whole-cell oral cholera vaccine (BivWC) is being increasingly used to prevent cholera. The presence of O-antigen-specific memory B cells (MBC) has been associated with protective immunity against cholera, yet MBC responses have not ...
Brie Falkard, Richelle C Charles, Wilfredo R Matias, Leslie M Mayo-Smith, J Gregory Jerome, Evan S Offord, Peng Xu, Pavol Kováč, Edward T Ryan, Firdausi Qadri, Molly F Franke, Louise C Ivers, Jason B Harris   +12 more
doaj   +1 more source

An Engineered Nano‐Vesicle Adjuvant Platform (ENAP) for Cytokine Delivery Enables a Novel Antigen‐Coordinated Vaccine Against Helicobacter pylori

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
ABSTRACT Despite the considerable potential of Helicobacter pylori (H. pylori) vaccines, their clinical efficacy has been hampered by inadequate mucosal immunity and suboptimal Th1/Th17 polarization. To address this, we engineered a novel nano‐adjuvant system using LPS‐modified recombinant outer membrane vesicles (rOMVs) derived from H.
Yinpan Shang, Xiran Zhang, Linwei Li, Xiaomin Yu, Lingbing Zeng, Yanli Cao, Ziwei Tao, Lu Shen, Shuaishuai Zhang, Chuangye Yang, Huizhen Tian, Ying Liang, Hanchen Liao, Xiaotian Huang, Qiong Liu   +14 more
wiley   +1 more source

Considerations for Oral Cholera Vaccine Use during Outbreak after Earthquake in Haiti, 2010−2011

Emerging Infectious Diseases, 2011
Oral cholera vaccines (OCVs) have been recommended in cholera-endemic settings and preemptively during outbreaks and complex emergencies. However, experience and guidelines for reactive use after an outbreak has started are limited. In 2010, after over a
Kashmira A. Date, Andrea Vicari, Terri B. Hyde, Eric D. Mintz, M. Carolina Danovaro-Holliday, Ariel Henry, Jordan W. Tappero, Thierry H. Roels, Joseph Abrams, Brenton T. Burkholder, Cuauhtémoc Ruiz-Matus, Jon Andrus, Vance Dietz   +12 more
doaj   +1 more source

Beyond Rotavirus: Persistence of Norovirus, Adenovirus, and Astrovirus in Paediatric Gastroenteritis in the Republic of Congo After Vaccine Introduction

Journal of Medical Virology, Volume 98, Issue 4, April 2026.
ABSTRACT Despite the introduction of rotavirus vaccines, gastroenteritis remains a major cause of paediatric morbidity and mortality in the Republic of Congo. This study investigated the prevalence and genetic diversity of non‐rotavirus enteric viruses including norovirus (NoV), adenovirus (AdV), and astrovirus (AstV) ten years after the introduction ...
Cedeche Lebraiche Durain Mboungou, Claujens Chastel Mfoutou Mapanguy, Do Duc Anh, Jeannhey Christevy Vouvoungui, Alain Maxime Mouanga, Vivaldie Mikounou Louya, Emmanuel Seun Kupoluyi, Raoul Ampa, Thirumalaisamy P. Velavan, Francine Ntoumi   +9 more
wiley   +1 more source

Vaccine specific immune response to an inactivated oral cholera vaccine and EPI vaccines in a high and low arsenic area in Bangladeshi children [PDF]

, 2013
Immune responses to the inactivated oral whole cell cholera toxin B (CTB) subunit cholera vaccine, Dukoral(®), as well as three childhood vaccines in the national immunization system were compared in children living in high and low arsenic contaminated ...
Sultana, Gazi Nurun Nahar, Nazim, Mohammad, Chowdhury, Mohiul, Alam, Mohammad Murshid, Svennerholm, Ann-Mari,, Saha, Amit, Hossain, Mohammad Bakhtiar, Hore, Samar Kumar, Qadri, Firdausi, Ahmed, Tanvir,   +9 more
core   +1 more source

Efficacy and Safety of Cholera Vaccines

Биопрепараты: Профилактика, диагностика, лечение, 2018
Cholera is an acute diarrheal disease caused by toxigenic strains of Vibrio cholerae O1 and O139 serogroups. It still remains a major  global healthcare problem.
A. A. Goryaev, L. V. Sayapina, Yu. I. Obukhov, V. P. Bondarev   +3 more
doaj   +1 more source

Evaluation of a Novel Climate‐Driven SIR Model for Cholera Prediction

GeoHealth, Volume 10, Issue 4, April 2026.
Abstract The causative agent of cholera, Vibrio cholerae, is a bacterium native to the aquatic environment and commensal to zooplankton, namely copepods. V. cholerae thrives in warm, moderately saline water and its incidence is strongly influenced by environmental factors, which have proven critical for predictive awareness of cholera by identifying ...
Bailey Magers, Kyle D. Brumfield, Rita R. Colwell, Antarpreet S. Jutla   +3 more
wiley   +1 more source

Immune Responses to the O-Specific Polysaccharide Antigen in Children Who Received a Killed Oral Cholera Vaccine Compared to Responses following Natural Cholera Infection in Bangladesh [PDF]

, 2019
Current oral cholera vaccines induce lower levels of protective efficacy and shorter durations of protection in young children than in adults. Immunity against cholera is serogroup specific, and immune responses to Vibrio cholerae lipopolysaccharide (LPS)
Xu, Peng, Wu-Freeman, Ying, Kováč, Pavol, Harris, Jason B., Alam, Mohammad Murshid, Rahman, Mohammad Arif, Eckhoff, Grace, Calderwood, Stephen B., Leung, Daniel T., Qadri, Firdausi, Ryan, Edward T., Charles, Richelle C., Khan, Ashraf I., Johnson, Russell A., Uddin, Taher, Yu, Yanan, Bufano, Meagan Kelly, Saha, Amit, Khanam, Farhana, Chowdhury, Fahima, LaRocque, Regina C., Aktar, Amena, Sultana, Tania   +22 more
core   +1 more source