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The oral mycobiome: Oral epithelial dysplasia and oral squamous cell carcinoma
Abstract Fungi, a diverse group of eukaryotic organisms, play distinct roles in health and disease. Recent advances in the field of mycobiology have enabled the characterization of the “human mycobiome.” The human mycobiome has extensively been studied in various disease models.
Theofilou, V.I. +7 more
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Oral cancer is one of the common cancers in the world causing high morbidity. Development of cancer is preceded by certain asymptomatic clinical lesions and conditions all together known as ‘oral potentially malignant disorders’.
Sonia Gupta +2 more
doaj +1 more source
Oral Epithelial Dysplasia and Premalignancy [PDF]
Leukoplakia and erythroplakia are two entities under the moniker of "oral potentially malignant disorders" that are highly associated with the presence of oral epithelial dysplasia (OED) at first biopsy, while lesions of submucous fibrosis develop OED after being present for years.
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Aim: To evaluate the expression of E-cadherin (E-cad) in oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC). Material and Method: Immunohistochemistry was used to detect E-cad expression in 20 cases each of normal oral mucosa, oral ...
Jaishree Sharma +5 more
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The expression of Cathepsin L in oral lichen planus
Background: Malignant transformation of oral lichen planus (OLP) was reported particularly in erosive type, however, it remains inconclusive. Cathepsin L was shown to promote tumor growth and invasion in many cancers. Therefore, cathepsin L expression in
Athip Kitkhajornkiat +4 more
doaj +1 more source
Immunophenotypic and Gene Expression Analyses of the Inflammatory Microenvironment in High-Grade Oral Epithelial Dysplasia and Oral Lichen Planus. [PDF]
Flores-Hidalgo A +6 more
europepmc +3 more sources
Oral lichen planus (OLP) and oral lichenoid lesions (OLL) can both present with histological dysplasia. Despite the presence of WHO-defined criteria for the evaluation of epithelial dysplasia, its assessment is frequently subjective (inter-observer ...
Marwa Zohdy +6 more
doaj +1 more source
Expression of p63 in potentially malignant and malignant oral lesions
Background: p63, a member of p53 family, known to be expressed in embryonic tissues and basal regenerative layers of many epithelial tissues in the adult, is also expressed in various benign and malignant lesions of body including lesions of oral cavity.
Anju Sinha +5 more
doaj +1 more source
Identification and Evaluation of Cancer Stem Cells in Oral Squamous Cell Carcinoma and Oral Epithelial Dysplasia Using NANOG: An Immunohistochemical Study. [PDF]
I A +5 more
europepmc +3 more sources
Histological grading of oral epithelial dysplasia: revisited [PDF]
Treatment of oral precancer is largely based on histological grading of epithelial dysplasia, despite the fact that this estimation is subjective and therefore carries a low reproducibility. The grade of epithelial dysplasia may not be proportional to the risk of malignant potential and clinical characteristics may complement therapeutic decisions ...
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