Results 51 to 60 of about 21,283 (244)

Effect of tobacco, alcohol, and smoking habits in oral precancer with histological proven epithelial dysplasia

Journal of Oral Biology and Craniofacial Research, 2012
Objectives: To assess the effect of risk factors tobacco, alcohol, and smoking habits in oral precancer patients with epithelial dysplasia status. Material and methods: The study sample included biopsy proven cases of 29 oral submucous fibrosis (OSMF ...
Seema Nayak, Saumya Chandra, Divya Mehrotra, Sumit Kumar, S.P. Agrawal, Sandeep Kumar, Madhu Mati Goel   +6 more
doaj   +1 more source

The role of Rho GTPases in facial morphogenesis

Developmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source

Morphometric analysis of suprabasal cell layer in oral epithelial dysplasia: A computer-assisted microscopic study

Journal of Pharmacy and Bioallied Sciences, 2020
Background: Oral leukoplakia is the most common precancerous lesion. Various grading systems based on histological findings have been proposed for dysplasia.
Viswanathan Prema, Thomson Thomas, Prasad Harikrishnan, Mani Viswanathan, Kenniyan Kumar Srichinthu, Krishnan Rajkumar   +5 more
doaj   +1 more source

Loss of the Y Chromosome in Oral Potentially Premalignant Disorders Predicts Malignant Progression: An Integrative Cross‐Species Multi‐Cohort Bioinformatic Study

Head &Neck, EarlyView.
ABSTRACT Background The loss of the Y chromosome (LOY) and the extreme down‐regulation of Y chromosome gene expression (EDY) are frequently observed in oral squamous cell carcinoma (OSCC). However, their roles in oral potentially malignant disorders (OPMDs) are unclear.
Rui Han, Jos B. Poell, Cristina Conde‐Lopez, Tuula Salo, Ina Kurth, Ruud H. Brakenhoff, Jochen Hess   +6 more
wiley   +1 more source

Oral epithelial dysplasia and oral cancer prevalence in routine white lesion biopsies – a 6-year retrospective study

Journal of Pre-Clinical and Clinical Research, 2020
Introduction Leukoplakia and oral lichen planus (OLP) are common diseases manifesting as white lesions that are considered potentially malignant disorders (PMD). Epithelial dysplasia may be an early sign of potency for the future transformation into oral
Maciej Kuzio, Karolina Wapniarska, Marian Danilewicz, Natalia Lewkowicz   +3 more
doaj   +1 more source

Oral epithelial dysplasia grading: Comparing the binary system to the traditional 3‐tier system, an actuarial study with malignant transformation as outcome [PDF]

, 2022
Marcelo Sperandio, Saman Warnakulasuriya, Andresa Borges Soares, Fabrício Passador‐Santos, Fernanda Viviane Mariano, Carmen Sílvia Passos Lima, João Figueira Scarini, Matheus Henrique Lopes Dominguete, Paulo de Camargo Moraes, Victor Ângelo Martins Montalli, Luíza Hellmeister, Vera Cavalcanti de Araújo   +11 more
openalex   +1 more source

Biopsy for Suspicious Oral Lesions: A Review From the American Head and Neck Society‐Cancer Prevention Service

Head &Neck, EarlyView.
ABSTRACT Background Oral cancer is often preceded by a precursor lesion. This presents an opportunity for early diagnosis and intervention. Method of biopsy and interpretation are not well standardized and novel methods of analysis are now being investigated.
James Christopher Gates, Heather Edwards, Alessandro Villa, Nick Purdy, Michael Troka, Peter Varela, Quinn Self, Yingci Liu, Yusuf Dundar, Patricia Joyce Brooks, Dauren Adilbay, Andrew Birkeland, John Cramer   +12 more
wiley   +1 more source

Grading of oral epithelial dysplasia: Points to ponder

Journal of Oral and Maxillofacial Pathology, 2015
Over the years many grading systems have been put forward in an attempt to obtain objectivity in grading oral epithelial dysplasia (OED). However, despite these efforts variability remains unresolved. Our study aimed to evaluate the intra- and inter-observer variability in grading OED, using World Health Organization (WHO), Smith and Pindborg and ...
Geetha, KM, Leeky, M, Narayan, TV, Sadhana, S, Saleha, J   +4 more
openaire   +3 more sources

Distribution and prognostic value of T‐cells in primary colorectal cancer and adjacent non‐tumor mucosa in stage IV versus stage I–III patients

International Journal of Cancer, EarlyView.
What's New? While colonic mucosa lymphocytes have been quantified in the context of inflammatory diseases, T‐cells in non‐tumor mucosa adjacent to colorectal cancer remain understudied. This study found that in stage IV colorectal cancer (synchronous liver metastasis), higher Foxp3+ T‐cell density and Foxp3+/CD4+ and Foxp3+/CD8+ T‐cell ratios in non ...
Esraa Ali, Wenjing Ye, Sergii Pavlov, Lenka Červenková, Filip Ambrozkiewicz, Ondřej Vyčítal, Petr Hošek, Ondřej Daum, Václav Liška, Kari Hemminki, Andriy Trailin   +10 more
wiley   +1 more source

Juvenile polyposis in a SMAD4‐mutated child: A call for early surveillance

JPGN Reports, EarlyView.
Abstract We report the case of a 10‐year‐old boy with hereditary hemorrhagic telangiectasia (HHT) and a family history of SMAD4‐related juvenile polyposis syndrome (JPS), presenting with hypoferritinaemia unresponsive to oral supplementation. Endoscopic evaluation revealed multiple gastrointestinal polyps, including duodenal, gastric, and colonic ...
Claudia Lorusso, Giuseppe Lassandro, Stefania Castellaneta, Valentina Palladino, Giovanni la Grasta, Vanessa Nadia Dargenio, Vittorio Labriola, Alberto Gaeta, Paola Giordano, Fernanda Cristofori, Ruggiero Francavilla   +10 more
wiley   +1 more source