Results 31 to 40 of about 1,433,667 (207)

Extending Service Beyond Active Duty: Generalizability of Rheumatoid Arthritis Research Conducted Among U.S. Veterans

Arthritis Care &Research, Accepted Article.
Biomedical research involving United States Veterans continues to advance healthcare beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where Veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both ...
Austin M. Wheeler, Joshua F. Baker, Jennifer L. Barton, Maria I. Danila, Tate M. Johnson, Kamini Kuchinad, Kaleb Michaud, Amir A. Razmjou, J. Steuart Richards, Namrata Singh, Isaac D. Smith, Katherine D. Wysham, Grant W. Cannon, Bryant R. England, Amy Joseph, Deana Lazaro, Katherine P. Liao, Courtney Loecker, Andreas Reimold, Beth I. Wallace, Ted R. Mikuls   +20 more
wiley   +1 more source

Relationship between risk of oral frailty and awareness of oral frailty among community-dwelling adults: a cross-sectional study

Scientific Reports
We aimed to investigate the relationship between the risk of oral frailty and awareness of oral frailty among Japanese adults in an adult dental health field study conducted in Kanagawa Prefecture.
Koichiro Irie, Yuki Mochida, Nandin Uchral Altanbagana, Shinya Fuchida, Tatsuo Yamamoto   +4 more
doaj   +1 more source

Establishment of a Mandarin Chinese Version of the Oral Frailty Index-8 and Exploration of the Association Between Oral Frailty and Sarcopenia

Geriatrics
Objective: The aim of our study was to introduce a Mandarin Chinese version of the oral frailty assessment and explore the relationship between oral frailty and sarcopenia.
Chen-Cheng Yang, Hsiang-Tai Chen, Katsuya Iijima, Tomoki Tanaka, Chia-Yen Dai, Sang-Ju Yu, Hung-Yi Chuang   +6 more
doaj   +1 more source

A Two-Year Longitudinal Study of the Association between Oral Frailty and Deteriorating Nutritional Status among Community-Dwelling Older Adults

, 2020
Background: Limited longitudinal studies exist to evaluate whether poor oral health and functions affect the incidence of deteriorating nutritional status.
Hiroki Inagaki, Masanori Iwasaki, Yuki Ohara, Shuichi Awata, Yutaka Watanabe, Keiko Motokawa, Shoji Shinkai, Maki Shirobe, Ayako Edahiro, Hirohiko Hirano   +9 more
core   +1 more source

Association of Oral Hypofunction with Frailty, Sarcopenia, and Mild Cognitive Impairment: A Cross-Sectional Study of Community-Dwelling Japanese Older Adults

, 2021
Oral hypofunction is a new concept that addresses the oral function of older adults. Few studies have investigated the relationship between oral hypofunction and general health conditions such as frailty, sarcopenia, and mild cognitive impairment.
Mahiro Beppu, Yoshinori Uchino, Takuro Kubozono, Kazuki Mori, Mitsuru Ohishi, Kenichi Kume, Yoshiaki Matsumura, Hiroaki Tabata, Hyuma Makizako, Yumiko Mishima, Kouta Yamashiro, Akihiko Tanaka, Toshihiro Takenaka, Maya Nakamura, Yutaro Higashi, Hiroshi Hijioka, Tomofumi Hamada, Takayuki Tabira, Tsuyoshi Sugiura, Yuichi Goto, Keitaro Nishi   +20 more
core   +1 more source

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, EarlyView.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source

Sarcopenic Dysphagia, Malnutrition, and Oral Frailty in Elderly: A Comprehensive Review. [PDF]

, 2022
Frailty is a highly prevalent condition in the elderly that has been increasingly considered as a crucial public health issue, due to the strict correlation with a higher risk of fragility fractures, hospitalization, and mortality.
Roberto de Sire, de Sire, Roberto, Francesco Agostini, Paola Emilia Ferrara, Raguso, Giuseppe, Invernizzi, Marco, Mario Migliario, Ferrillo, Martina, Agostini, Francesco, Roccuzzo, Andrea, Martina Ferrillo, Lippi, Lorenzo, Sergio Riso, de Sire, Alessandro, Riso, Sergio, Gianpaolo Ronconi, Ferrara, Paola Emilia, Marco Invernizzi, Migliario, Mario, Andrea Roccuzzo, Giuseppe Raguso, Lorenzo Lippi, Alessandro de Sire, Ronconi, Gianpaolo   +23 more
core   +2 more sources

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Prevention of frailty, sarcopenia and oral frailty in elderly [PDF]

, 2020
Frailty, sarcopenia and oral frailty are important concepts to prevent nursing care in elderly. Nutrition and physical activity may play a key role of interventions for a loss ofmuscle mass. We need interprofessional work (IPW) for prevention of frailty,
澤田, 篤史, 38306
core   +1 more source