Results 41 to 50 of about 1,433,667 (207)

Towards an operational definition of oral frailty: A e-Delphi study [PDF]

, 2023
ObjectivesBuilding upon our recently developed conceptual definition of oral frailty (the age-related functional decline of orofacial structures), this e-Delphi study aims to develop an operational definition of oral frailty by identifying its components.
Visser, Anita, Schimmel, Martin, Verhoeff, Merel C.; id_orcid, Limor Avivi-Arber, Joke Duyck, Yutaka Watanabe, Gobbens, Robbert J. J., Gobbens, Robbert J J, Lin, Chia-Shu, Karl G.H. Parisius, Verhoeff, Merel C., Kossioni, Anastassia, Barbara Janssens, Iijima, Katsuya, Gobbens, Robbert J.J., Parisius, Karl G.H.; id_orcid, Avivi-Arber, Limor, Müller, Frauke, Martin Schimmel, Duck, Joke, Janssens, Barbara, Gerald McKenna, Katsuya Iijima, Lijima, Katsuya, Chia-Shu Lin, Frank Lobbezoo, Parisius, Karl G.H., McKenna, Gerald, Anita Visser, Robbert J.J. Gobbens, McKenna, Gerry; id_orcid, Merel C. Verhoeff, Parisius, Karl G H, Duyck, Joke, Anastassia Kossioni, Parisus, Karl G. H., Frauke Müller, Watanabe, Yutaka, Kossioni, Anasstasia, Verhoeff, Merel C, Hirano, Hirohiko, Lobbezoo, Frank, Hirohiko Hirano, Lin, Chia Shu   +43 more
core   +2 more sources

Integrating Genetics With Epidemiological Measurements Identifies Burden QTLs of Inflammatory Bowel Disease across 20 Countries

Advanced Science, EarlyView.
The burden quantitative trait locus (bQTL) analysis integrates epidemiological data from GBD study with genotype of 2 621 978 SNPs from 2414 individuals in 1000 Genomes Project across 20 countries. rs7633471 shows the strongest effect that each increase in centi‐allele frequency of the allele C associated with 10.00 decrease of age‐standardized ...
Chen Sun, Siyu Wei, Junxian Tao, Haiyan Chen, Chi Yan, Jiacheng Wang, Jing Xu, Lian Duan, Yuanbo Zhan, Yuping Zou, Ruilin Li, Linna Yuan, Wei She, Songlin Lu, Ning Wang, Qinduo Ren, Yan Guo, Yuan Xu, Chang Wang, Hongsheng Tian, Chen Zhang, Yu Dong, Guoping Tang, Zhenwei Shang, Yongshuai Jiang, Wenhua Lv, Mingming Zhang, Hongchao Lyu   +27 more
wiley   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

QRICH1 Disrupts Endoplasmic Reticulum Homeostasis and Amplifies NF‐κB Signaling in Periodontal Ligament Stem Cells to Exacerbate Diabetic Periodontitis

Advanced Science, EarlyView.
QRICH1 has been established as a key factor contributing to impaired osteogenic potential and accelerated apoptosis of PDLSCs in diabetic periodontitis. QRICH1 not only significantly enhances UPR‐associated apoptotic signaling but also amplifies NF‐κB‐mediated inflammatory responses. Its inhibition restores osteogenic capacity and reduces alveolar bone
Han Li, Xiaoyu Yang, He Wang, Yunchun Kuang, Yiyao Hu, Houxuan Li, Shuhong Li, Deping Zeng, Jie Li, Jinlin Song   +9 more
wiley   +1 more source

Prevalence of frailty and its association with oral hypofunction in older adults: a gender perspective

BMC Oral Health, 2023
Background Previous studies have indicated an association between oral hypofunction and frailty in community-dwelling older adults. However, this issue has not been evaluated in institutionalized older patients.
Karla Cruz-Moreira, Ludwig Alvarez-Cordova, Carla González-Palacios Torres, Peter Chedraui, José Jouvin, José Juan Jiménez-Moleón, Rocío Barrios-Rodríguez   +6 more
doaj   +1 more source

Investigating Eating Behaviors and Symptoms of Oral Frailty Using Questionnaires

, 2019
A questionnaire survey was conducted to investigate eating behavior and the subjective symptoms of oral frailty, and to examine the relationship between them. A total of 744 subjects with ages over 65 years were included.
Tsukasa Hihara, Tetsuo Ichikawa, Takaharu Goto   +2 more
core   +1 more source

Ultrasound‐Activated Piezoelectric Neuroimmune Hydrogel Orchestrates Neurogenesis‐Macrophage Crosstalk in Diabetic Wound Healing

Advanced Science, EarlyView.
In this work, we design an ultrasound‐activated piezoelectric hydrogel platform (AOEF@AP5+US) that reprograms neurogenesis‐macrophage crosstalk as an integrated strategy to overcome the intertwined barriers of chronic inflammation, peripheral neuropathy, and impaired regeneration in diabetic wounds.
Kai Wang, Shaowen Zhuo, Binyu Song, Jinan Chen, Xin Zhao, Sijia Li, Shuang You, Dong Jiang, Yuedong Chen, Juanli Dang, Tong Wang, Baolin Guo, Zhou Yu, Baoqiang Song   +13 more
wiley   +1 more source

Epidemiology and risk factors of oral frailty among older people: an observational study from China

BMC Oral Health
Objectives This study aimed to compare the prevalence of oral frailty among community-dwelling older people in Nanjing, China with the usage of different measurements, and to investigate the potential risk factors of oral frailty.
Yueheng Yin, Yue Zhao, Yang Fei, Ying Liu, Yun Ji, Enfang Shan, Shuzhen Niu, Ying Xing, Jingjing Ding, XianWen Li   +9 more
doaj   +1 more source

Prevalence of Physical and Oral Frailty Among the Community-Dwelling Geriatric Population of Thrissur, Kerala

Journal of the Indian Academy of Geriatrics
Objective: Data on the prevalence of frailty in Kerala are sparse. The objective of this study was to estimate the prevalence of frailty among community-dwelling older people in Kerala and explore the sociodemographic factors associated with physical and
K. N. Sandhya, Beena Varma, Chandrashekar Janakiram, Priya Vijayakumar, Niveditha Kartha   +4 more
doaj   +1 more source

Do malnutrition, sarcopenia and frailty overlap in nursing-home residents?

, 2020
Objectives: To study the prevalence and overlap between malnutrition, sarcopenia and frailty in a selected group of nursing home (NH) residents. Design Cross-sectional descriptive study. Setting: Nursing homes (NH). Participants: 92 residents taking part
Faxen-Irving, G.,, Boström, A-M, Franzen, E., Luiking, Y., Luiking, Y.,, Grönstedt, H.,, Vikström, S., Wimo, A., Boström, A-M,, Grönstedt, H., Seiger, Å.,, Faxen-Irving, G., Seiger, Å., Vikström, S.,, Cederholm, Tommy,, Cederholm, Tommy, Franzen, E.,, Wimo, A.,   +17 more
core   +1 more source