Results 71 to 80 of about 11,814,383 (250)

Oral frailty subtypes and influencing factors in older patients with ischemic stroke: a latent profile analysis

Frontiers in Public Health
ObjectiveTo analyze potential subtypes and influencing factors of oral frailty in older ischemic stroke patients. To support clinical professionals in precisely identifying high-risk populations and to offer a scientific foundation for the creation of ...
Yutong Zhou, Lixia Xie, Wen Zhang, Yao Chen, Pan Li, Yifan Ou, Haoke Shi, Xinhong Yin   +7 more
doaj   +1 more source

Periostin‐CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy

Advanced Science, EarlyView.
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Tiantian Wu, Ruotong Li, Xiaoyue Zhang, Dandan Chen, Jianmeng Yang, Mengmeng Li, Yuhan Yin, Ya Wang, Yuqiu Tian, Haoling Yan, Dan Cui, Jiangping Song, Gaoliang Ouyang   +12 more
wiley   +1 more source

The relationship between eHealth literacy and oral frailty among older adults: the serial mediating effects of self-efficacy and oral health

BMC Oral Health
Background Oral frailty can cause many adverse consequences, including by impairing basic oral functions such as chewing and speaking; furthermore, it is closely related to overall systemic health. In the digital age, this study explores the relationship
Jie Wu, Xin-xin Wang, Min Xu, Kang-ping Liu, Li-ling Xu, Ying Zhang   +5 more
doaj   +1 more source

Oral frailty and its influencing factors among ICU patients with oral endotracheal intubation: a cross-sectional study

Frontiers in Medicine
ObjectiveTo investigate the level and factors associated with oral frailty among ICU patients with oral endotracheal intubation, and to provide references for the construction of targeted nursing intervention programs in the future.MethodsIn this single ...
Min Shi, Lei Li, Huaixiang Zhai
doaj   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

ORAL FRAILTY INDEX-8 QUESTIONNAIRE’S VALIDITY & ASSOCIATION WITH SARCOPENIA & PHYSICAL PERFORMANCE IN OLDER ADULTS

Innovation in Aging
Abstract Oral frailty (OF) is the age-related decline in oral function, and is associated with negative outcomes, including aspiration, malnutrition, and physical frailty. Despite its importance, validated tools for OF assessment are limited, preventing early detection and intervention. The Oral Frailty Index-8 (OFI-8) is a questionnaire
Hernandez, Herb Howard, Lim, Celestine, Lim, Jun Pei, Chia, Jia Qian, Yeo, Audrey, Tan, Cai Ning, Lim, Wee Shiong, Chew, Justin   +7 more
openaire   +1 more source

A covariance-based test for shared frailty in multivariate lifetime data [PDF]

, 2012
We decompose the score statistic for testing for shared finite variance frailty in multivariate lifetime data into marginal and covariance-based terms.
Kimber, Alan, Sarker, Shah-Jalal
core   +1 more source

Mitochondria‐Targeted Nanotherapeutics: A Promising Strategy in Modulating Mitochondrial Function, Transfer, and Transplantation

Advanced Science, EarlyView.
This review summarizes the pathogenic role of mitochondria in diseases and highlights mitochondrial transfer and transplantation as emerging therapeutic strategies. It systematically discusses how nanomaterials are engineered to facilitate these processes, and critically examines the current challenges and future perspectives for their clinical ...
Yuanyuan Su, Zhiyan Gong, Jiao Mu, Lili Huang, Pengfei Yang, Chenli Zhang, Lingshan Zhao, Liling Yang, Jun Deng, Xiaohui Liao   +9 more
wiley   +1 more source

Correlation between oral frailty and severity of osteoporosis in elderly women [PDF]

Jichu yixue yu linchuang
Objective To investigate the association between oral frailty and the severity of osteoporosis in elderly women, identify the risk threshold of oral frailty for osteoporosis, and provide evidence for joint assessment in patients seeking care at primary ...
LI Xiaoxiao, BIAN Lili, DING Jing, DU Xueping
doaj   +1 more source

Prevalence of Oral Pain and Barriers to use of Emergency Oral Care Facilities Among Adult Tanzanians. [PDF]

, 2008
Oral pain has been the major cause of the attendances in the dental clinics in Tanzania. Some patients postpone seeing the dentist for as long as two to five days.
Kikwilu Emil, Febronia Kokulengya Kahabuka, Masalu, Joyce Rose, Kikwilu, Emil Namakuka, Senkoro, Ahadieli Raphael, Kahabuka Febronia, Masalu, J.R., Joyce Rose Masalu, Emil Namakuka Kikwilu, Ahadieli Raphael Senkoro, Kahabuka, Febronia Kokulengya, Senkoro Ahadieli, Masalu Joyce, Kikwilu, E.N., Kahabuka, F.K., Senkoro, A.R.   +15 more
core   +2 more sources