Results 221 to 230 of about 36,741 (290)

Tirzepatide and Cardiovascular Outcomes: A Narrative Review of Mechanisms, Efficacy and Implications for Heart Failure Management

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
Integrated framework for tirzepatide in HFpEF management. Through metabolic, haemodynamic, structural and anti‐inflammatory pathways, tirzepatide modifies the disease trajectory of HFpEF, leading to improvements in symptoms, functional capacity and reduction in HF events.
Hamza A. Abdul‐Hafez, Ameer Awashra, Sosana Bdir, Sarah Saife, Qasem Salah, Mohammed Barbarawi, Thabet Swaileh, Ahmed Emara, Mohamed S. Elgendy, Abdalhakim Shubietah   +9 more
wiley   +1 more source

Sulfated Polysaccharides in the Hallmarks of Metabolic Syndrome: Functions and Mechanisms

Food Frontiers, Volume 7, Issue 1, January 2026.
The SPs sources are very diverse, including various fishes, sea cucumbers, seaweeds, etc. These SPs are able to improve the glucose and lipid metabolism disorders, hormonal dysregulation, oxidative stress, inflammatory response, complications, and gut homeostasis of MetS by regulating biochemical indicators related to MetS. ABSTRACT Metabolic syndrome (
Fuqiang Zhao, Chuan Li, Xin Zhang, Kexue Zhu, Chao Zhao, Deming Gong, Lulu Zhu, Yongcheng Li, Jun Cao, Shaoping Nie   +9 more
wiley   +1 more source

Biological aging, left ventricular dysfunction and mortality in patients with heart failure with preserved ejection fraction. [PDF]

NPJ Aging
Xu X, Huang Z, Xu X, Liu M, Huang R, Xiong Z, Guo Y, Zhang S, Zhou Z, Tang Z, Liao X, Zhuang X.   +11 more
europepmc   +1 more source

New Insights Into Ginseng and Clove Supplementation: Alleviating Obesity by Reducing Leptin Resistance and Reshaping the Gut Microbiota

Food Frontiers, Volume 7, Issue 1, January 2026.
AEGC conferred substantial resistance to weight gain and reduced food intake. AEGC may alleviate LR by regulating the levels of LEP and ADP. AEGC elevated the diversity of gut microbiota and reconstructed the composition. Changes such as CAG‐873 in gut microbiota may be the reason why AEGC alleviates LR.
Weifeng Ni, Shen Yao, Shichao Li, Shichao Liu, Liwei Sun, Daqing Zhao, Zhengqi Dong, Siming Wang, Weinan Wang, Meichen Liu   +9 more
wiley   +1 more source

Effects of Jinhua instant dark tea in patients with type 2 diabetes mellitus: study protocol for a multicenter, open-label, randomized controlled trial. [PDF]

Trials
Chen N, Zhao K, Xu Y, Qi Y, Cheng D, Zhao M, Meng D, Shi L, Yu J.   +8 more
europepmc   +1 more source

Fuc‐S, a New Degraded Polysaccharide From Fucoidan, Alleviates Type 2 Diabetes‐Associated Liver Injury Through Modulating Gut Microbiota

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
Fuc‐S alleviated type 2 diabetes‐associated liver injury through gut microbiota‐SCFA‐liver axis regulation. Fuc‐S treatment significantly improved glucose tolerance, lipid metabolism, and liver function, while reducing hepatic steatosis and serum ALT/AST levels. Fuc‐S reinforced intestinal barrier integrity by upregulating tight junction proteins (ZO‐1
Bin Du, Caihong Cheng, Jinxiu Feng, Yue Liang, Wang Tao, Baojun Xu, Jiao Peng, Guangtao Zhang, Yuedong Yang   +8 more
wiley   +1 more source

Future horizons in diabetes treatment: hypoglycemic activity of [1,2,4]triazino[2,3-<i>c</i>]quinazoline derivatives. [PDF]

Front Endocrinol (Lausanne)
Trzhetsynskyi S, Nosulenko I, Kinichenko A, Skoryna D, Berest H, Shvets V, Voskoboinik O, Kovalenko S, Petakh P, Kamyshnyi O.   +9 more
europepmc   +1 more source

Glucose‐Lowering Properties of a Tea Formulation Containing Citrullus lanatus Peel, Ananas comosus Peel, and Mentha spicata L. Leaf Extracts in Dexamethasone‐Induced Insulin‐Resistant Wistar Rats

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
The optimized tea blend exhibited high antioxidant activity and contained significant amounts of flavonoids, tannins, polyphenols, and vitamin C. In diabetic rats, the tea formulation significantly improved glycemic control, reduced lipid profiles, and enhanced liver and kidney function.
Irwin Leoda Begnone, Laurette Blandine Mezajoug Kenfack, Rosane Matsinkou Soh   +2 more
wiley   +1 more source

Hepatic Transaminases Evaluation in Patients with Onychomycosis Treated with Oral Antifungals: A Retrospective Study with 229 Patients. [PDF]

Skin Appendage Disord
Bertolucci Ferrero L, Valinoto GCJ, Carvalho G, Veasey JV.   +3 more
europepmc   +1 more source

The Association Between Amino Acids and the Onset and Progression of Type 2 Diabetes Mellitus: A Comprehensive Analysis Based on UK Biobank Database. [PDF]

J Diabetes Res
Yang J, Wu Z, Fang J, Zhang Z, Huang J, Wang Y, Cui J, Ruan S, Yan Q, Wu Q, Chen S, Hou B, Huang S, Zhang C.   +13 more
europepmc   +1 more source