Results 31 to 40 of about 13,041 (208)

Sabin Vaccine in Poliomyelitis Eradication: Achievements and Risks

Journal of Pure and Applied Microbiology, 2019
Poliomyelitis eradication using the oral polio vaccine (OPV), also known as the Sabin vaccine, has been a major medical achievement led by the World Health Organization (WHO) and various countries.
Omar A. Nafi, Bashar Ramadan
doaj   +1 more source

Immunodeficiency-associated Vaccine-Derived Poliovirus Type 3 in Infant, South Africa, 2011

Emerging Infectious Diseases, 2012
Patients with primary immunodeficiency are prone to persistently excrete Sabin-like virus after administration of live-attenuated oral polio vaccine and have an increased risk for vaccine-derived paralytic polio.
Nicksy Gumede, Vongani Muthambi, Barry D. Schoub   +2 more
doaj   +1 more source

Poliovirus Excretion in Children with Primary Immunodeficiency Disorders, India

Emerging Infectious Diseases, 2017
Prolonged excretion of poliovirus can occur in immunodeficient patients who receive oral polio vaccine, which may lead to propagation of highly divergent vaccine-derived polioviruses (VDPVs), posing a concern for global polio eradication.
Madhu Chhanda Mohanty, Manisha Rajan Madkaikar, Mukesh Desai, Prasad Taur, Uma Prajwal Nalavade, Deepa Kailash Sharma, Maya Gupta, Aparna Dalvi, Snehal Shabrish, Manasi Kulkarni, Jahnavi Aluri, Jagadish Mohanrao Deshpande   +11 more
doaj   +1 more source

Introduction of Inactivated Poliovirus Vaccine and Trivalent Oral Polio Vaccine/Bivalent Oral Polio Vaccine Switch in the African Region [PDF]

The Journal of Infectious Diseases, 2017
The Polio Eradication and Endgame Strategic plan outlines the phased removal of oral polio vaccines (OPVs), starting with type 2 poliovirus-containing vaccine and introduction of inactivated polio vaccine in routine immunization to mitigate against risk of vaccine-associated paralytic polio and circulating vaccine-derived poliovirus.
Tevi-Benissan, Carol, Okeibunor, Joseph, du Châtellier, Gaël Maufras, Assefa, Afework, Biey, Joseph Nsiari-Muzenyi, Cheikh, Dah, Eshetu, Messeret, Anya, Blanche-Philomene, Dao, Halima, Nasir, Yusuf, Akanmori, Bartholomew Dicky, Mihigo, Richard   +11 more
openaire   +2 more sources

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

A Phase 2 Trial of Frexalimab, a CD40L Antagonist, in Adolescents and Adults With Recent‐Onset Type 1 Diabetes (FABULINUS): Rationale and Study Design

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas, Baerbel Rotthaeuser, Niels Porksen, Pascale Labard, My‐Liên Nguyên‐Pascal, Mathieu Coudert, Baptiste Berthou, Marie Baccara‐Dinet, Gabor Boka, Mark Peakman, Felix Reschke, Michael J. Haller   +11 more
wiley   +1 more source

Guideline for the Diagnosis and Management of Heritable IFNAR1 Deficiency in Oceania

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Autosomal recessive interferon alpha and beta receptor subunit 1 (IFNAR1) deficiency is a rare and heritable inborn error of immunity (IEI) predisposing individuals to severe and life‐threatening viral infections. It is more common in people of Western Polynesian ancestry, with estimates of around one in six thousand live births affected, due ...
Cecilia Verryt, Paul Gray, Peter McNaughton, Jane Peake, Melanie Wong, George Aho, Emma Best, Maia Brewerton, Flora Lutui, Litara Esera Tulifau, Rebecca Qin, Satupa‘itea Viali, Petine White, Andrew Wood, See‐Tarn Woon, Theresa Cole, Alberto Pinzon Charry, Kuang‐Chih Hsiao   +17 more
wiley   +1 more source

Stakeholders' opinions and questions regarding the anticipated malaria vaccine in Tanzania [PDF]

, 2016
Within the context of combined interventions, malaria vaccine may provide additional value in malaria prevention. Stakeholders' perspectives are thus critical for informed recommendation of the vaccine in Tanzania.
Abdulla, S, Exavery, A, Ali, A, Abdulla, Salim, Elisa Sicuri, Romore, Idda, Sicuri, Elisa, Salim Abdulla, Kafuruki, Shubi, Shubi Kafuruki, Kimweri, Angela, Ali Ali, Angela Kimweri, Marcel Tanner, Kimweri, A, Mtenga, S, Romore, I, Tanner, Marcel, Sicuri, E, Idda Romore, Exavery, Amon, John Lusingu, Amon Exavery, Tanner, M, Mtenga, Sally, Sally Mtenga, Ali, Ali, Lusingu, J, Kafuruki, S, Lusingu, John   +29 more
core   +1 more source

Health Screening and Post‐Arrival Services for Refugee Children From Afghanistan

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim To examine refugee health screening and services for Afghan children in the unique context of emergency expedited humanitarian resettlement in Melbourne, Australia. Methods Retrospective audit of Afghan children who attended a specialist child refugee health service between August 2021–April 2024. Results Participants included 218 children
Amy Williamson, Eva Sudbury, Rija Khanal, Jade Woon, Jennifer Schaefer, Georgia Paxton   +5 more
wiley   +1 more source

Eradikasi Polio

Sari Pediatri, 2017
Poliomielitis atau yang lebih dikenal dengan polio merupakan penyakit menular yang dapat menyebabkan kelumpuhan dan atrofi otot yang ireversibel, bahkan kematian pada anak.
Hindra Irawan Satari, Laila Fitri Ibbibah, Sidik Utoro   +2 more
doaj   +1 more source