Prolonged Excretion of Poliovirus among Individuals with Primary Immunodeficiency Disorder: An Analysis of the World Health Organization Registry. [PDF]
, 2017 Individuals with primary immunodeficiency disorder may excrete poliovirus for extended periods and will constitute the only remaining reservoir of virus after eradication and withdrawal of oral poliovirus vaccine.
Dooling, Kathleen +8 more
core +2 more sources
Public Health Challenges, Volume 4, Issue 3, September 2025.ABSTRACT Background In March 2024, a circulating vaccine‐derived poliovirus type 2 (cVDPV2) was isolated in environmental samples (ESs) collected at the Mabella Sawmill Bridge environmental surveillance (ES) site. The Ministry of Health and its partners responded to the outbreak by conducting a novel oral poliovirus vaccine type 2 (nOPV2) nationwide ...
Desmond M. Kangbai +15 more
wiley +1 more source
An Opportunity Not To Be Missed: Vaccination as an Entry Point for Hygiene Promotion and Diarrhoeal Disease Reduction in Nepal [PDF]
, 2013 This report aims to ascertain whether or not vaccination programmes offer a useful entry point for hygiene promotion and to define options for piloting and scaling up of a hygiene promotion intervention in ...
Katie Greenland +2 more
core
Population Immunity against Serotype-2 Poliomyelitis Leading up to the Global Withdrawal of the Oral Poliovirus Vaccine: Spatio-temporal Modelling of Surveillance Data. [PDF]
, 2016 BACKGROUND: Global withdrawal of serotype-2 oral poliovirus vaccine (OPV2) took place in April 2016. This marked a milestone in global polio eradication and was a public health intervention of unprecedented scale, affecting 155 countries.
Blake, Isobel M +9 more
core +4 more sources
Microbial Biotechnology, Volume 18, Issue 9, September 2025.Human neurotropic viruses like SARS‐CoV‐2, HSV, HOPV and RSV pose significant risks due to their ability to invade and persist in the nervous system. Stapled peptides represent a promising therapeutic approach with enhanced stability, target affinity and bioavailability, emerging as an effective strategy for neutralising human neurotropic viruses ...
Sanskruti Patil +4 more
wiley +1 more source
Epidemiological Characteristics of Poliomyelitis During the 21st Century (2000-2013) [PDF]
, 2014 Poliovirus is the pathogenic agent of paralytic poliomyelitis that belongs to the picornaviridae family. Poliomyelitis has an extended history dating over to the Egyptian eighteenth dynasty.
Ahmad, T. (Tahir) +3 more
core +1 more source
Extensive myelitis after oral polio vaccination: MRI features
Journal of the Belgian Society of Radiology, 2014 A 7-year-old boy presented with fever and ataxia 20 days after oral polio vaccination. Magnetic resonance imaging showed extensive myelitis, involving both anterior and posterior horns of the gray matter. Complete posttreatment recovery was evident. Postvaccinal myelitis after oral polio vaccination, of either infectious or immune mediated etiology, is
Kozic, D. +5 more
openaire +6 more sources
The roles of resident, central and effector memory CD4 T cells in protective immunity following infection or vaccination [PDF]
, 2018 Immunological memory provides rapid protection to pathogens previously encountered through infection or vaccination. CD4 T cells play a central role in all adaptive immune responses.
Gray, Joshua I. +2 more
core +1 more source
Does oral polio vaccine have non-specific effects on all-cause mortality? Natural experiments within a randomised controlled trial of early measles vaccine. [PDF]
, 2016 BACKGROUND: BCG and measles vaccine (MV) may have beneficial non-specific effects (NSEs). If an unplanned intervention with a vaccine (a natural experiment) modifies the estimated effect in a randomised controlled trial (RCT), this suggests NSEs. We used
Aaby, Peter +6 more
core +3 more sources
A highly immunogenic UVC inactivated Sabin based polio vaccine
npj VaccinesDespite their efficacy, the currently available polio vaccines, oral polio vaccine (OPV) and inactivated polio vaccine (IPV), possess inherent flaws posing significant challenges in the global eradication of polio.
Gregory J. Tobin +9 more
doaj +1 more source