Results 71 to 80 of about 1,716,393 (201)

Planning for globally coordinated cessation of bivalent oral poliovirus vaccine: risks of non-synchronous cessation and unauthorized oral poliovirus vaccine use. [PDF]

BMC Infect Dis, 2018
Background Oral polio vaccine (OPV) containing attenuated serotype 2 polioviruses was globally withdrawn in 2016, and bivalent OPV (bOPV) containing attenuated serotype 1 and 3 polioviruses needs to be withdrawn after the certification of eradication of ...
Duintjer Tebbens RJ, Hampton LM, Thompson KM.   +2 more
europepmc   +2 more sources

Bee products as alternatives in the treatment of viral infections

Journal of the Science of Food and Agriculture, Volume 106, Issue 1, Page 33-54, 15 January 2026.
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba, Łukasz Marek, Jerzy Stojko, Anna Rzepecka‐Stojko   +3 more
wiley   +1 more source

Breast Cancer: Molecular Pathogenesis, Targeted Therapy, Screening, and Prevention

MedComm, Volume 7, Issue 1, January 2026.
The review manuscript examines the molecular pathogenesis, screening, prevention advances, and evolving targeted therapies in breast cancer. It highlights the integration of AI and multiomics for precision prevention and personalized treatment, pointing toward future directions in equitable cancer care.
Huijun Lei, Jinzhen Fu, Wei Gu, Hongjin Qiao, Huixue Guo, Zijian Chen, San Ming Wang, Tianhui Chen   +7 more
wiley   +1 more source

Vaccine-Derived Poliovirus Infection among Patients with Primary Immunodeficiency and Effect of Patient Screening on Disease Outcomes, Iran

Emerging Infectious Diseases, 2019
Patients with immunodeficiency-associated vaccine-derived poliovirus (iVDPV) are potential poliovirus reservoirs in the posteradication era that might reintroduce polioviruses into the community.
Mohammadreza Shaghaghi, Shohreh Shahmahmoodi, Ali Nili, Hassan Abolhassani, Seyedeh Panid Madani, Ahmad Nejati, Maryam Yousefi, Yaghoob M. Kandelousi, Mona Irannejad, Shiva Shaghaghi, Seyed Mohsen Zahraei, Sussan Mahmoudi, Mohammad Mehdi Gouya, Reza Yazdani, Gholamreza Azizi, Nima Parvaneh, Asghar Aghamohammadi   +16 more
doaj   +1 more source

Beyond PD‐1/PD‐L1: New Immune Checkpoints and Therapeutic Combinations in Cancer Immunotherapy

Medicine Bulletin, Volume 2, Issue 1, Page 61-93, January 2026.
ABSTRACT Recently, immune checkpoint inhibitors (ICIs), particularly PD‐1/PD‐L1 and CTLA‐4 inhibitors, have revolutionized cancer treatment, significantly improving survival rates for various malignancies. However, ICI therapies targeting single checkpoints on T cells still face numerous challenges, such as low response rates and post‐treatment ...
Yangyang Li, Zizhen Kang, Yanyun Du
wiley   +1 more source

Myocarditis in the Modern Era: Navigating Diagnosis, Innovative Treatments, the COVID‐19 Challenge and the Role of Artificial Intelligence

Cardiology Research and Practice, Volume 2026, Issue 1, 2026.
Myocarditis is an inflammatory disease of the myocardium with diverse aetiologies, ranging from infections and autoimmune processes to drug‐induced reactions. Clinical manifestations vary widely from mild chest discomfort to life‐threatening complications such as acute heart failure, cardiogenic shock and sudden cardiac death. Although the diagnosis of
Kevin Mohee, Ibrahim Antoun, Robert Ambrogetti, Mahmoud Eldesouky, Riyaz Somani, André Ng, Sanjay S. Bhandari, Irfan Ahmad   +7 more
wiley   +1 more source

Excretion and clearance of Sabin-like type 3 poliovirus in a child diagnosed with severe combined immunodeficiency

Human Vaccines & Immunotherapeutics
Children with primary immunodeficiency disorder (PID) are at higher risk of developing vaccine-associated paralytic poliomyelitis (VAPP) or vaccine-derived polioviruses (VDPV) infection when inadvertently expose to poliovirus vaccine, oral (OPV). A pilot
Ning Yao, Yang Liu, Zhi-Yong Zhang, Min Tian, Wu-Juan Xie, Hua Zhao, Hong Yang, Lance E. Rodewald, Ning Wen, Zun-Dong Yin, Fu-Zhen Wang, Qing Wang, Jia-Wei Xu   +12 more
doaj   +1 more source

Mucosal Immunity: The Key to Combating Enteroviruses and Beyond

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Enteroviruses (EVs) lead to 10–15 million symptomatic infections each year in the United States alone. EVs enter through either the gastrointestinal or respiratory mucosa, depending on the specific virus. Since these mucosal surfaces are the primary entry points for viruses, mucosal immunity serves as a crucial first line of defense.
Nida Kalam, Vinod R. M. T. Balasubramaniam, Poorani Gurumallesh Prabu   +2 more
wiley   +1 more source

Next‐Generation Immune Checkpoints and Tumor Microenvironment Modulation in Cancer Immunotherapy

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Immunotherapy has reshaped the oncology landscape by enabling the immune system to recognize and eliminate malignant cells. Although immune checkpoint inhibitors (ICIs) targeting cytotoxic T‐lymphocyte‐associated protein 4 (CTLA‐4), programmed cell death‐1 (PD‐1), and programmed death‐ligand 1 (PD‐L1) have achieved durable responses in several cancers,
Jhommara Bautista, Carolina E. Echeverría, Iván Maldonado-Noboa, Joseth Adatty-Molina, Salomé Suárez Urresta, Emily C. Coral-Riofrio, Salomé Araujo-Abad, Nikolaos C. Kyriakidis, Andrés López-Cortés, Poorani Gurumallesh Prabu   +9 more
wiley   +1 more source

Environmental Surveillance of Polioviruses in Armenia, Colombia before Trivalent Oral Polio Vaccine Cessation

Viruses, 2019
Although acute flaccid paralysis (AFP) surveillance is the “gold standard” for detecting cases of polio, environmental surveillance can provide supplementary information in the absence of paralytic poliomyelitis cases.
María Mercedes González, Magile C. Fonseca, Carlos Andrés Rodríguez, Alejandra María Giraldo, José Joaquín Vila, Jhon Carlos Castaño, Leonardo Padilla, Luis Sarmiento   +7 more
doaj   +1 more source