Results 41 to 50 of about 3,898,040 (219)
Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2
Advanced Science, EarlyView.Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang +15 more
wiley +1 more source
Solutions used in oral rehydration therapy: current status. [PDF]
, 2003 Presentamos una revisión literaria sucinta, histórica, científica y apli-cada, de las soluciones empleadas en la Terapia de Rehidratación Oral (TRO) diseñada por la Organización Mundial de la Salud (OMS) para el manejo de las Enfermedades Diarreicas (ED)
Rodríguez Hernández, Myriam +1 more
core
Wellcome Open Research, 2017 Background: Diarrhoea complicates over half of admissions to hospital with severe acute malnutrition (SAM). World Health Organization (WHO) guidelines for the management of dehydration recommend the use of oral rehydration with ReSoMal (an oral ...
Kirsty A. Houston +2 more
doaj +1 more source
Advanced Science, EarlyView.Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Xueqiang Wang +17 more
wiley +1 more source
Homemade sugar-salt solution for oral rehydration: Knowledge of mothers and caregivers
South African Family Practice, 2005 Background: Worldwide, it is estimated, that more than two million children under the age of five die annually as a result of gastroenteritis with dehydration. Up to 95% of these cases can be treated successfully with oral rehydration therapy. The aim of
H. Dippenaar +5 more
doaj +1 more source
Advanced Science, EarlyView.FAK orchestrates a mechanical barrier limiting nanomedicine accumulation in solid tumors by coupling ECM remodeling with cytoskeletal tension. Genetic or pharmacological FAK inhibition dismantles this barrier, enhances clathrin‐mediated uptake and penetration, and overcomes delivery limitations to improve antitumor efficacy.
Tian Zhao +11 more
wiley +1 more source
How to Predict Oral Rehydration Failure in Children With Gastroenteritis [PDF]
, 2017 OBJECTIVES:: Oral rehydration is the standard in most current guidelines for young children with acute gastroenteritis (AGE). Failure of oral rehydration can complicate the disease course, leading to morbidity due to severe dehydration.
Oostenbrink, R. (Rianne) +11 more
core +1 more source
Oral Rehydration Therapy and Feeding Replaces Total Parenteral Nutrition: A Clinical Vignette. [PDF]
J Gen Intern Med, 2016 A 27-year-old patient with spina bifida and a high output loss of water and electrolytes from her ileostomy was successfully liberated from dependency on total parenteral nutrition and intravenous fluid and electrolyte replacement by the use of a rice ...
Wright SM, Noon MJ, Greenough WB.
europepmc +2 more sources
Loss of Intestinal MSTN Promotes GLP‐1 Secretion Through SGLT1 Palmitoylation
Advanced Science, EarlyView.Intestinal MSTN deficiency enhances glucose‐stimulated GLP‐1 secretion and glucose tolerance in high‐fat diet‐fed mice. Mechanistically, loss of MSTN promotes YY1‐associated ZDHHC20 expression, increasing SGLT1 S‐palmitoylation at Cys301 and its plasma membrane localization in L cells.
Sheng‐Zhong Han +16 more
wiley +1 more source