Results 71 to 80 of about 3,898,040 (219)

Oral rehydration therapy in emergency departments

open access: yesJornal de Pediatria, 2011
To describe the management of acute diarrhea in emergency departments with emphasis on the type of hydration and exploring factors associated with prescription of oral rehydration therapy vs. intravenous rehydration therapy for children with dehydration that is not severe.This was a descriptive study conducted from January to May of 2008 observing case
Auxiliadora Damianne P Vieira da, Costa   +1 more
openaire   +2 more sources

Ginsenoside Rh1 Attenuates Alzheimer's Disease‐Like Deficits by Modulating Oxidative Stress and Mitochondrial Dysfunction via SIRT1‐Related Signaling

open access: yesPhytotherapy Research, EarlyView.
Rh1 attenuates oxidative stress and mitochondrial dysfunction through SIRT1‐related signaling. ABSTRACT Alzheimer's disease (AD) remains a progressive neurodegenerative disorder with limited therapeutic options. Ginsenoside Rh1 has been reported to possess neuroprotective properties, yet its specific role and underlying mechanisms in AD are not fully ...
Shi‐Lu Li   +10 more
wiley   +1 more source

Rehydration therapy efficacy of viral gastroenteritis in children [PDF]

open access: yesРМЖ. Мать и дитя
M.K. Bekhtereva1,2, A.M. Komarova1 1Children's Research and Clinical Center of Infectious Diseases of the Federal   Medical-Biological Agency, St. Petersburg, Russian Federation 2St.
M.K. Bekhtereva, A.M. Komarova
doaj  

Oxypaeoniflorin Attenuates Alcohol‐Associated Liver Disease, Potentially Involving TEAD4‐Mediated Inflammatory Signaling Cascades

open access: yesPhytotherapy Research, EarlyView.
Oxypaeoniflorin (Opae) alleviates alcohol‐associated liver disease (ALD) by suppressing the TEAD4‐NLRP3 transcriptional axis. In hepatocytes, Opae inhibits YAP/TEAD4‐mediated NLRP3 inflammasome activation, thereby downregulating Lipin1/Srebp1‐associated lipid dysregulation.
Jiang‐Tao Zhong   +5 more
wiley   +1 more source

4′‐Hydroxywogonin Attenuates Hepatocellular Carcinoma Progression by Suppressing Gas6/Axl‐PI3K/AKT Signaling

open access: yesPhytotherapy Research, EarlyView.
4′‐Hydroxywogonin, a flavonoid derived from Scutellaria baicalensis, inhibits hepatocellular carcinoma progression partly by suppressing Gas6/Axl‐PI3K/AKT signaling, inducing cell cycle arrest and apoptosis, and reducing metastatic potential. It also suppresses xenograft tumor growth without evident hepatotoxicity.
Chi‐Yuan Chen   +11 more
wiley   +1 more source

A Cytoplasmic pH Sensor Redefines Gating in Bacterial Urea Channels and Acid Resistance

open access: yesSmall, EarlyView.
Bacterial survival in acidic environments requires pH‐gated urea channels. Utilizing complementary approaches, we identify a conserved cytoplasmic glutamic acid residue as a pH sensor in UreI channels. Whereas Gram‐positive bacteria rely solely on this sensor, Gram‐negative bacteria employ a dual‐sensor mechanism with periplasmic residues, revealing a ...
Anna Stoib   +10 more
wiley   +1 more source

Reverse Micelles: The Gateway for Oral (Poly)Peptide Delivery

open access: yesSmall, EarlyView.
RM achieve superior oral peptide delivery through high loading capacity, strong lipophilicity, and a low‐hydration microenvironment that protects against enzymatic degradation. Meanwhile, dRM provides favorable permeation‐enhancing interactions and a consistent safety profile, collectively driving enhanced oral performance.
Marlene Ramona Schmidt   +2 more
wiley   +1 more source

Oral administration of tannins and flavonoids in children with acute diarrhea: a pilot, randomized, control-case study

open access: yesItalian Journal of Pediatrics, 2018
Background AG is the most common cause of pediatric consultations among children between 2 and 5 years of age and it still leads to high mortality and morbidity.
Marina Russo   +5 more
doaj   +1 more source

Chromatin Remodeller BRD9 Orchestrates Odontoblastic Differentiation via Coordinating RUNX2‐KLF4

open access: yesCell Proliferation, EarlyView.
During odontoblast lineage commitment, the chromatin remodeller BRD9 acts as a critical epigenetic coordinator, orchestrating the chromatin landscape to facilitate synergistic binding of key transcription factors RUNX2 and KLF4 to target loci for odontogenesis.
Wenrui Zeng   +8 more
wiley   +1 more source

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