Results 91 to 100 of about 213,434 (307)
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
Advanced Science, EarlyView.β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit +20 morewiley +1 more sourceThe administration of multipotent stromal cells at precancerous stage precludes tumor growth and epithelial dedifferentiation of oral squamous cell carcinoma [PDF]
, 2017 Multipotent stromal cells (MSCs) are envisioned as a powerful therapeutic tool. As they home into tumors, secrete trophic and vasculogenic factors, and suppress immune response their role in carcinogenesis is a matter of controversy.Arango Rodríguez, Martha, Bruna, Flavia Alejandra, Conget, Paulette, Espinoza, Iris, Plaza, Anita +4 morecore +1 more sourceCore Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion
Advanced Science, EarlyView.FUT8‐mediated core fucosylation of CD47 at N111 blocks SMURF1 binding and reduces CD47 ubiquitination and degradation. Blocking N111 glycosylation reduces CD47 expression and promotes macrophage phagocytosis of tumor cells. Furthermore, ablating CD47 core fucosylation boosts CD103+ dendritic cells (DCs) infiltration, increases natural killer (NK) cell ...Yuting Cao, Siyuan Chai, Mingyang Li, Xiaoming Chen, Jiating Hu, Bingyi Lin, Liming Wu, Wen Yi, Qiang Zhu +8 morewiley +1 more sourceGenomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas [PDF]
, 2018 This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing
molecular features of squamous cell carcinomas (SCCs) from five sites associated with ...Abdel-Rahman, Mohamed H., Abeshouse, Adam, Adebamowo, Clement, Adebamowo, Sally N., Agnew, Kathy, Ahn, Keunsoo, Ajani, Jaffer A., Akbani, Rehan, Akbani, Rehan, Akeredolu, Teniola, Al-Ahmadie, Hikmat, Al-Ahmadie, Hikmat, Albert, Monique, Alexopoulou, Iakovina, Ally, Adrian, Alvaro, Domenico, Anderson, Matthew L., Andry, Chris, Antenucci, Anna, Anur, Pavana, Anur, Pavana, Appelbaum, Elizabeth L., Aredes, Natália D., Armenia, Joshua, Arnaout, Angel, Asa, Sylvia L., Auman, J. Todd, Aymerich, Marta, Aziz, Dina, Bailey, Matthew, Balasundaram, Miruna, Balu, Saianand, Barnett, Gene, Barnholtz-Sloan, Jill S., Barrett, Wendi, Bartlett, John, Bathe, Oliver, Baudin, Eric, Baylin, Stephen, Becker, Karl-Friedrich, Beer, David, Behera, Madhusmita, Behrens, Carmen, Bell, Debra, Bell, Sue, Bellair, Michelle, Bennett, Joseph, Benz, Christopher, Benz, Christopher, Berchuck, Andrew, Berger, Ashton C., Bergeron, Alain, Berkowitz, Ross, Bernard, Brady, Beroukhim, Rameen, Beuschlein, Felix, Bifulco, Carlo, Bigner, Darell, Birrer, Michael, Birsoy, Kivanc, Bocklage, Therese, Bodenheimer, Tom, Bondaruk, Jolanta, Bootwalla, Moiz S., Borad, Mitesh, Borgia, Jeffrey A., Bossler, Aaron, Botnariuc, Natalia, Boussioutas, Alex, Bowen, Jay, Bowlby, Reanne, Bowlby, Reanne, Bowman, Rayleen, Bradford, Carol, Bragazzi, Maria Consiglia, Brat, Daniel J., Breggia, Anne, Brennan, Kevin, Brewer, Cathy, Brimo, Fadi, Broaddus, Russell, Brooks, Denise, Broom, Bradley M., Broudy, Thomas, Bryce, Alan H., Bubley, Glenn, Bueno, Raphael, Bullman, Susan, Burnette, Andrew, Byers, Lauren Averett, Caesar-Johnson, Samantha J., Calatozzolo, Chiara, Campbell, Joshua D., Campo, Elias, Campos, Benito, Caraman, Irina, Cardinale, Vincenzo, Carey, Francis, Carey, Thomas, Carlotti, Carlos Gilberto, Carlsen, Rebecca, Carney, Michael, Carpino, Guido, Carroll, Peter R., Carter, Candace, Carvalho, Andre L., Castle, Erik, Castro, Patricia D., Catto, James, Cebulla, Colleen M., Cernat, Mircea, Chabot, John, Chakravarty, Debyani, Chambwe, Nyasha, Chan, June M., Chan, Timothy A., Chandan, Vishal, Chang, Kyle, Chatila, Walid K., Chemencedji, Inga, Chen, Amy, Chen, Chu, Chen, Jianhong, Chen, Ting-Wen, Chen, Zhong, Cheng, Feixiong, Cheng, Hui, Cherniack, Andrew D., Cherniack, Andrew D., Chesla, David, Chevalier, Simone, Cheville, John, Chiu, Hua-Sheng, Cho, Juok, Chuah, Eric, Chudamani, Sudha, Chung, Ki, Cibulskis, Carrie, Clipca, Adrian, Coarfa, Cristian, Colman, Howard, Cope, Leslie, Copland, John A., Corcoran, Niall, Cordes, Matthew G., Costello, Tony, Cottingham, Sandra, Couce, Marta, Covington, Kyle, Crain, Daniel, Cramer, Daniel, Creaney, Jenette, Creighton, Chad J., Creighton, Chad J., Cuppini, Lucia, Curley, Erin, Cuzzubbo, Stefania, Czerniak, Bogdan, Danilova, Ludmila, Davis, Amy, de Bruijn, Ino, de Carvalho, Ana C., de Krijger, Ronald, De Rienzo, Assunta, De Rose, Agostino, Defreitas, Timothy, Delman, Keith, Demchok, John A., Desjardins, Laurence, Devine, Karen, Deyarmin, Brenda, Dhalla, Noreen, Dhanasekaran, Renumathy, Dhankani, Varsha, Dhir, Rajiv, Diao, Lixia, Dimeco, Francesco, Ding, Li, Dinh, Huyen, Dinkin, Mikhail, Dipersio, John, Disaia, Philip, Doddapaneni, Harshavardhan, Donehower, Larry, Donehower, Lawrence A., Doruc, Serghei, Dos Santos, Jose Sebastião, Dottino, Peter R., Drake, Bettina, Drill, Esther, Drummond, Jennifer, Drwiega, Paul, Dubina, Michael, Duell, Rebecca, Duffy, Elizabeth R., Eckman, John, Edenfield, W. Jeffrey, Eijckenboom, Wil, Elder, J. Bradley, Engel, Jay, Eschbacher, Jennifer, Esmaeli, Bita, Evason, Kimberley, Facciolo, Francesco, Fan, Cheng, Fan, Huihui, Fan, Huihui, Fantacone-Campbell, J. Leigh, Farnell, Michael, Farver, Carol, Fassnacht, Martin, Fehrenbach, Ashley, Felau, Ina, Feldman, Michael, Feltmate, Colleen, Ferguson, Martin L., Finocchiaro, Gaetano, Flores, Elsa R., Flotte, Thomas, Fong, Kwun M., Force, Seth, Forgie, Ian, Frazer, Scott, Fregnani, José H., Fronick, Catrina C., Fujimoto, Junya, Fulop, Jordonna, Fulton, Lucinda A., Fulton, Robert S., Gabra, Hani, Gabriel, Stacey B., Galbraith, Joseph, Gao, Galen F., Gao, Jianjiong, Gardner, Johanna, Gastier-Foster, Julie M., Gaudio, Eugenio, Gay, Carl M., Gehlenborg, Nils, Gerken, Mark, Gershenwald, Jeffrey, Getz, Gad, Gevaert, Olivier, Ghossein, Ronald, Giama, Nasra, Gibbs, Richard A., Gilbert, Sebastien, Gillis, Ad, Gimenez-Roqueplo, Anne-Paule, Giné, Eva, Giordano, Thomas, Girard, Nicolas, Giuliante, Felice, Glenn, Pat, Glenn, Robert, Godwin, Andrew K., Godwin, Eryn M., Gonzalez, Ana Maria Angulo, Goodman, Marc, Gopalan, Anuradha, Goparaju, Chandra, Gorincioi, Ghenadie, Govindan, Ramaswamy, Graefen, Markus, Grazi, Gianluca, Grizzle, William E., Gross, Benjamin E., Guillermo, Armando López, Gunaratne, Preethi, Guo, Charles, Ha, Gavin, Haddad, Andrea, Hagedorn, Curt H., Hale, Walker, Han, Yi, Hanh, Phan Thi, Hansen, Paul, Harr, Jodi, Hartmann, Arndt, Haydu, Lauren, Hayes, D. Neil, Hayes, D. Neil, Hayward, Nicholas, Heath, Sharon, Hegde, Apurva, Hegde, Apurva M., Heiman, David I., Heins, Zachary J., Henderson, Joel, Hermes, Beth, Hernandez, Brenda, Herold-Mende, Christel, Hersey, Peter, Hess, Julian, Hibshoosh, Hanina, Hilty, Joe, Hinoue, Toshinori, Ho, Thai, Hoadley, Katherine A., Hoadley, Katherine A., Holt, Robert, Hooke, Jeffrey A., Hoon, Dave, Horowitz, Neil, Houck, John, Hovens, Christopher, Hoyle, Alan P., Hu, Hai, Hu, Jianhong, Huland, Hartwig, Hung, Nguyen Phi, Huntsman, David, Hutter, Carolyn M., Iacocca, Mary, Ittmann, Michael, Jacobus, Laura, Jakrot, Valerie, Janssen, Klaus-Peter, Jefferys, Stuart R., Jimeno, Antonio, Jones, Corbin D., Jones, Steven J. M., Ju, Zhenlin, Juhl, Hartmut, Jungk, Christin, Junker, Kerstin, Kakavand, Hojabr, Kalkanis, Steven, Kanchi, Rupa S., Kanchi, Rupa S., Kandoth, Cyriac, Kang, Koo Jeong, Karlan, Beth Y., Kasaian, Katayoon, Kasapi, Melpomeni, Kastl, Alison, Kebebew, Electron, Kefford, Richard, Kelley, Robin K., Kemp, Rafael, Kendall, Sara, Kendler, Ady, Kendrick, Michael, Khuri, Fadlo, Kibel, Adam, Kim, Jaegil, Knijnenburg, Theo, Knudson, Michael, Knutson, Tina, Kocher, Jean-Pierre, Kohl, Bernard, Kopp, Karla, Korchina, Viktoriya, Korkut, Anil, Korpershoek, Esther, Korst, Robert, Kovatich, Albert J., Kramer, Roger, Kucherlapati, Melanie H., Kucherlapati, Raju S., Kumar, Bahavna, Kundra, Ritika, Kvecher, Leonid, Kycler, Witold, La, Konnor, Lacombe, Louis, Ladanyi, Marc, Lai, Phillip H., Laird, Peter W., Laird, Peter W., Landen, Charles N., Landrum, Lisa, Lang, James, Larson, Caroline, Latour, Mathieu, Lau, Kevin, Lawrence, Michael S., Lazar, Alexander J., Lazar, Alexander J., Le, Xuan, Lechan, Ronald, Lee, Darlene, Lee, Jung Il, Lee, Kenneth, Lee, Sandra, Lehman, Norman L., Leinonen, Kalle, Leraas, Kristen M., Levine, Douglas A., Lewis, Lora, Ley, Timothy, Li, Jun, Li, Wei, Liang, Han, Lichtenberg, Tara M., Lin, Pei, Linehan, W. Marston, Ling, Shiyun, Lipp, Eric, Liptay, Michael J., Liu, Jia, Liu, Wenbin, Liu, Xiuping, Liu, Yuexin, Liu, Yuexin, Logothetis, Christopher, Lohavanichbutr, Pawadee, Lolla, Laxmi, Long, Georgina, Longatto-Filho, Adhemar, Looijenga, Leendert, Lu, Yiling, Luketich, James, Luna, Augustin, Lyadov, Vladimir, Ma, Deqin, Ma, Wencai, Ma, Yussanne, Madan, Rashna, Maglinte, Dennis T., Magliocca, Kelly, Maithel, Shishir, Mallery, David, Malykh, Andrei, Mandt, Randy, Manikhas, George, Mann, Graham, Mannel, Robert, Mannelli, Massimo, Mardis, Elaine R., Mariamidze, Armaz, Mariani, Odette, Marino, Mirella, Marks, Jeffrey, Marra, Marco A., Martignetti, John A., Martin, Julie, Mattei, Luca, Mayo, Michael, Mccall, Shannon, Mcgraw, Mary, Mckercher, Ginette, Mclellan, Michael D., Mclendon, Roger, Mcpherson, Christopher, Meier, Sam, Melamed, Jonathan, Meng, Shaowu, Meric-Bernstam, Funda, Merola, Roberta, Mes-Masson, Anne-Marie, Metwalli, Adam R., Meyerson, Matthew, Mieczkowski, Piotr A., Mikkelsen, Tom, Milhem, Mohammed, Miller, Christopher A., Miller, Judy, Miller, Michael, Mills, Gordon B., Mirsaidi, Cyrus, Moiseenko, Fedor, Moncrieff, Marc, Moore, Kathleen, Moore, Richard A., Moran, Cesar, Morgan, Margaret, Morris, Scott, Morrison, Carl, Morton, Donna, Mose, Lisle E., Moser, Catherine, Moxley, Katherine, Moyer, Jeffey, Mungall, Andrew J., Mungall, Karen, Mungall, Karen L., Mura, Sergiu, Mural, Richard J., Murawa, Dawid, Muto, Michael, Muzny, Donna, Myers, Jerome, Nagorney, David, Nair, Praveen, Naresh, Rashi, Naska, Theresa, Nelson, Mark, Ng, Kwok-Shing, Nguyen, Phuong, Nissan, Moriah G., Noble, Michael S., Noss, Ardene, Noushmehr, Houtan, O'Brien, Daniel, O'Neill, Brian Patrick, Ochoa, Angelica, Ojesina, Akinyemi I., Olabode, Oluwole, Olson, Jeffrey J., Omberg, Larsson, Oosterhuis, Wolter, Ostrom, Quinn T., Owonikoko, Taofeek, Pacak, Karel, Paklina, Oxana, Parfitt, Jeremy, Park, Joong-Won, Parker, Joel S., Pass, Harvey, Patel, Tushar, Paulauskis, Joseph, Pedamallu, Chandra Sekhar, Pennell, Nathan A., Penny, Robert, Perin, Alessandro, Perou, Amy H., Perou, Charles M., Petersen, Gloria, Peterson, Lisa, Peto, Myron, Peto, Myron, Phillips, Joanna, Phillips, Sarah M., Phu, Bui Duc, Piché, Alain, Pickens, Alan, Pickering, Curtis R., Pihl, Todd, Pilarski, Robert, Pinero, Edna M. Mora, Pinto, Peter A., Pirtac, Maria, Pollo, Bianca, Pool, Mark, Porten, Sima, Postier, Russel, Potapova, Olga, Powers, James, Prados, Michael, Prince, Mark, Prunello, Marcos, Que, Florencia, Quinn, Michael, Quintero-Aguilo, Mario, Rabeno, Brenda, Rader, Janet S., Rai, Karan, Ramalingam, Suresh, Ramirez, Nilsa C., Ramondetta, Lois, Rao, Arvind, Rassl, Doris M., Rathmell, W. Kimryn, Raut, Chandrajit P., Raymond, Daniel, Reis, Rui M., Reuter, Victor, Reynolds, Sheila, Reznik, Ed, Rice, David, Richards, William G., Rintoul, Robert C., Rivera, Michael, Roach, Jeffrey, Roberts, Lewis, Robertson, A. Gordon, Robertson, A. Gordon, Robinson, Bruce, Roggin, Kevin, Roman-Roman, Sergio, Rosenthal, Howard G., Rozek, Laura, Rubin, Mark A., Rustgi, Anil K., Ryan, Michael, Saad, Fred, Sadeghi, Sara, Sadeghi, Sara, Saksena, Gordon, Sanchez-Vega, Francisco, Sander, Chris, Sankarankuty, Ajith, Santibanez, Jireh, Sastre, Xavier, Sauter, Guido, Saw, Robyn, Scapulatempo-Neto, Cristovam, Scarpace, Lisa, Schadendorf, Dirk, Schein, Jacqueline E., Schiffman, Mark, Schilero, Cathy, Schlomm, Thorsten, Schmidt, Heather K., Schmidt, Laura S., Schoenfield, Lynn, Schultz, Andre, Schultz, Nikolaus, Schumacher, Steven E., Scolyer, Richard, Secord, Angeles, Seder, Christopher W., Sekhon, Harman, Senecal, Kelly, Sepulveda, Antonia, Setdikova, Galiya, Sexton, Katherine C., Shabunin, Alexey, Shannon, Kerwin, Sharp, Alexis, Shelley, Carl Simon, Shelton, Candace, Shelton, Troy, Shen, Hui, Shen, Hui, Shen, Ronglei, Sheridan, Robert, Sherman, Mark, Sheth, Margi, Shi, Yan, Shih, Juliann, Shih, Juliann, Shimmel, Kristen, Shin, Dong M., Shinbrot, Eve, Shipman, Cassaundra, Shmulevich, Ilya, Shriver, Craig D., Sica, Gabriel, Sifri, Suzanne, Sigmund, Rita, Signoretti, Sabina, Silveira, Henrique C. S., Simko, Jeffry, Simon, Ronald, Simons, Janae V., Singer, Samuel, Singh, Bhuvanesh, Singh, Rosy, Sipahimalani, Payal, Skelly, Tara, Sloan, Andrew E., Slotta-Huspenina, Julia, Smallridge, Robert, Smith, Jennifer, Smith-McCune, Karen, Smolenski, Kathy, Smyrk, Thomas, Sofia, Heidi J., Soloway, Matthew G., Somiari, Stella, Sood, Anil, Spellman, Paul, Spillane, Andrew, Stancul, Irina, Stanton, Melissa, Staugaitis, Susan M., Steele, Ruth, Stepa, Serghei, Stern, Marc-Henri, Stoehr, Christine, Stoehr, Robert, Stoop, Hans, Stretch, Onathan, Stuart, Joshua M., Stuart, Joshua M., Su, Tao, Sumazin, Pavel, Sumer, S. Onur, Sun, Qiang, Sun, Yichao, Swanson, Patricia, Swisher, Elizabeth, Synott, Maria, Tam, Angela, Tamakawa, Raina, Tamboli, Pheroze, Tan, Donghui, Tang, Yufang, Tarnuzzer, Roy, Taubert, Helge, Tavobilov, Mikhail, Taylor, Alison M., Taylor, Barry S., Tcaciuc, Diana, Tennstedt, Pierre, Thiessen, Nina, Thomas, George, Thompson, Eric, Thompson, John, Thompson, R. Houston, Thompson, Timothy, Thorp, Richard, Thorsson, Vesteinn, Tien, Nguyen Viet, Timmers, Henri, Tirapelli, Daniela, Tischler, Arthur, Torbenson, Michael, Troncoso, Patricia, Tsai, Kenneth Y., Tsao, Anne, Tse, Kane, Tucker, Kelinda, Têtu, Bernard, Unterberg, Andreas, Urba, Walter, Valdivieso, Federico, Van Bang, Nguyen, Van Den Berg, David J., van Kessel, Kim E., Van Meir, Erwin G., Van Tine, Brian, Van Waes, Carter, Vandenberg, Scott, Veluvolu, Umadevi, Vicha, Ales, Vidal, Daniel O., Vocke, Cathy D., Voet, Doug, von Deimling, Andreas, Voronina, Olga, Wach, Sven, Wakely, Paul, Waldmann, Jens, Walker, Joan, Walter, Vonn, Wan, Yunhu, Wang, Chen, Wang, Jing, Wang, Jing, Wang, Jioajiao, Wang, Linghua, Wang, Min, Wang, Timothy, Wang, Zhining, Warnick, Ronald, Weinstein, John N., Weinstein, John N., Weisenberger, Daniel J., Wentzensen, Nicolas, Westervelt, Peter, Wheeler, David A., Wilkerson, Matthew D., Williams, Felicia, Wilmott, James, Wilson, Richard K., Wise, Lisa, Wistuba, Ignacio, Wiznerowicz, Maciej, Wolf, Gregory, Wolinsky, Yingli, Wong, Christopher K., Wong, Christopher K., Wong, Tina, Worrell, Robert, Wu, Ye, Wullich, Bernd, Xi, Liu, Yang, Hannah, Yang, Ian, Yang, Ju Dong, Yang, Liming, Yau, Christina, Yau, Christina, Yena, Peggy, Zach, Leigh Anne, Zaren, Howard, Zelinka, Tomas, Zenklusen, Jean C., Zhang, Hailei, Zhang, Hongxin, Zhang, Hongzheng, Zhang, Jiashan (Julia), Zhang, Jiexin, Zhang, Lizhi, Zhang, Wei, Zhao, Fengmei, Zhou, Jane H., Zhou, Wanding, Zmuda, Erik, Zuna, Rosemary, Zuna, Rosemary, Zwarthoff, Ellen C. +784 morecore +2 more sourcesGPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Advanced Science, EarlyView.Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang +11 morewiley +1 more source
