Results 71 to 80 of about 124,134 (216)

Safe Omission of Postoperative Neck Irradiation in Selected pN0 Patients With Locally Advanced Oral Cavity Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Postoperative radiotherapy is the standard treatment for locally advanced oral squamous cell carcinoma (OSCC); however, the indication for neck irradiation (NI) in pN0 patients remains debatable. We evaluated whether the omission of NI compromises outcomes in pT3–T4 pN0 patients treated with adequate neck dissection (ND).
Mathilde Mirallié, Anouchka Modesto, Marie Pajiep, Sébastien Vergez, Jérôme Sarini, Lucie Piram, Céline Dalmasso, Benjamin Vairel, Emilien Chabrillac, Agnès Dupret‐Bories   +9 more
wiley   +1 more source

Visualization of Scattered Tumor Regression Following Neoadjuvant Chemoimmunotherapy With a Novel Intraoperative PET/CT Scanner

Head &Neck, EarlyView.
ABSTRACT Background Neoadjuvant chemoimmunotherapy is being explored in locally advanced head and neck squamous cell carcinoma (HNSCC), yet the spatial patterns of pathologic response and clinical implications remain poorly characterized. Methods A 79‐year‐old female with recurrent left oral tongue SCC (PD‐L122C3 Combined Positive Score 90) who ...
Andreja Radevic, Joaquin Austerlitz, Ashtyn McAdoo, Kyrionna Golliday, Takeshi Takahashi, Mitra Mehrad, Adam J. Rosenberg, Barbara A. Murphy, Eben Rosenthal, Michael C. Topf   +9 more
wiley   +1 more source

The Role of Multicancer Early Detection Tests in Head and Neck Squamous Cell Carcinoma: A Case Series

Head &Neck, EarlyView.
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC) lacks an established screening program, and most cases are diagnosed at advanced stages. Multi‐cancer early detection (MCED) blood‐based assays represent a promising approach, yet real‐world clinical experience with MCED‐identified HNSCC remains limited.
Abhinav Talwar, Olivia Ben‐Levy, Nikhil Sriram, Sandeep Samant   +3 more
wiley   +1 more source

Comparison of SKA1 serum levels in oral potentially malignant disorders and oral squamous cell carcinoma

Journal of the Pakistan Medical Association
Objective: To compare serum levels of spindle and kinetochore-associated complex subunit 1 in oral potentially malignant disorders and oral squamous cell carcinoma.
Samreen Khan, Muhammad Mohiuddin Alamgir, Uzma Bukhari, Muhammad Shuja Farrukh   +3 more
doaj   +1 more source

Robotic‐Assisted Extended Sistrunk Approach (RESA) for Salvage Surgery After Head and Neck Irradiation

Head &Neck, EarlyView.
ABSTRACT Background The robotic‐assisted extended “Sistrunk” approach (RESA) is a minimally invasive technique providing access to hypopharyngeal and laryngeal structures via a submental incision and vallecular pharyngotomy, bypassing the base of tongue.
Bartosz Wojtera, Avinash Beharry, Karma Lambercy, Pascaline Dübi, Jelena Todic, Christian Simon   +5 more
wiley   +1 more source

From Nodal Metastasis to Oncologic Recurrence in Tongue and Oral Floor Squamous Cell Carcinoma: Distinct Failure Patterns and Clinicopathological Risk Profiles

Head &Neck, EarlyView.
ABSTRACT Background Locoregional recurrence remains a clinically relevant problem in oral squamous cell carcinoma (OSCC). Whether local, ipsilateral nodal, and contralateral nodal failure represent distinct disease processes with different clinicopathological associations has not been systematically evaluated.
Jannik Ketschau, Jonathan Mohr, Alex Grabenhorst, Hannes Singer, Helena Kram, Cornelius Leopold, Nils Krautkremer, Katharina Pippich, Klaus‐Dietrich Wolff, Lucas M. Ritschl   +9 more
wiley   +1 more source

Stereotactic Body Radiotherapy (SBRT) of Previously Unirradiated Mucosal Head and Neck Squamous Cell Carcinoma (SCC)

Head &Neck, EarlyView.
ABSTRACT Purpose To evaluate the efficacy and safety of stereotactic body radiation therapy (SBRT) in previously untreated primary mucosal head and neck cancer (HNC) patients unfit for conventional radiation therapy. Materials and Methods Retrospective analysis of previously unirradiated primary SCC mucosal HNC patients treated with SBRT from 2011 to ...
Mohammed Aldohan, Irene Karam, Amir H. Safavi, Lee Chin, Liying Zhang, Ethan Gooanratne, Madette Galapin, Antoine Eskander, Kevin Higgins, Danny Enepekides, Ian Poon   +10 more
wiley   +1 more source

Cancer stem cell markers in patterning differentiation and in prognosis of oral squamous cell carcinoma

Tumor Biology, 2017
Differentiation is a major histological parameter determining tumor aggressiveness and prognosis of the patient; cancer stem cells with their slow dividing and undifferentiated nature might be one of the factors determining the same.
Simple Mohanta, Gangotri Siddappa, Sindhu Govindan Valiyaveedan, Ravindra Dodda Thimmasandra Ramanjanappa, Debashish Das, Ramanan Pandian, Samanta Sekhar Khora, Moni Abraham Kuriakose, Amritha Suresh   +8 more
doaj   +1 more source

Early Feasibility of Registration of Micro‐PET/CT Scans to Annotated 3D Specimen Models

Head &Neck, EarlyView.
ABSTRACT Background Intraoperative 18F‐fluorodeoxyglucose (18F‐FDG) micro‐positron emission tomography/computed tomography (micro‐PET/CT) is an emerging modality for margin assessment. Prior to clinical use, micro‐PET/CT margin distances must be correlated with gold‐standard histopathology.
Joaquin Austerlitz, Andreja Radevic, Ashtyn McAdoo, Kyrionna Golliday, Cheng Ye, Daniel Fabbri, Adam J. Rosenberg, Marcus Balanky, Anas Alabkaa, Kim A. Ely, Mitra Mehrad, Spencer Roark, Eben Rosenthal, Michael C. Topf   +13 more
wiley   +1 more source

Vascular Testing to Overcome Anatomical Contraindication: Fibula Free Flap in Bilateral Peronea Arteria Magna

Head &Neck, EarlyView.
ABSTRACT Background Peronea arteria magna (PAM) is an established contraindication for fibula free flap due to concern for vascular compromise of the lower leg. Methods This is a case of a 74‐year‐old male with a history of multiply recurrent oral cavity cancer who had undergone prior free flap reconstruction who presented with a new oral cavity ...
Jacob Beiriger, Richard Bavier, Ziga Cizman, Faris Galambo, Kaohinani J. Longwolf, Richard Cannon, Hilary McCrary, Marcus Monroe   +7 more
wiley   +1 more source