Results 51 to 60 of about 119,825 (261)

seed lectin inhibits oral squamous cell carcinoma tumorigenesis by suppressing N6-methyladenosine modification–mediated SRY-box transcription factor 2 expression

Journal of International Medical Research
Objective Studies have indicated that combining Maackia amurensis seed lectin with first-line chemotherapeutic agents enhances the efficacy of treatment for oral squamous cell carcinoma.
Yong Du, Haiyan Yang, Hongguang Lian, Dan Li, Weina Liu, Linyuan Zhao, Yufeng Zhang   +6 more
doaj   +1 more source

Proliferating Cell Nuclear Antigen in Premalignancy and Oral Squamous Cell Carcinoma [PDF]

Journal of Clinical and Diagnostic Research, 2015
Introduction: Cancer has multifactorial aetiology and is a multistep process involving initiation, promotion and tumour progression. Cellular proliferation is one of the important indicators for the biologic aggressiveness of a malignant lesion.
Chandrashekar Poosarla, Maya Ramesh, K. Ramesh, Swetha Gudiseva, Sekar Bala, Murali Sundar   +5 more
doaj   +1 more source

Oral squamous cell carcinoma associated with myiasis [PDF]

BMJ Case Reports, 2012
Myiasis is a general term for infection by fly larvae feeding on the host's necrotic or living tissue. Although infestation by fly larvae is much more prevalent in animals, it is a relatively frequent in occurrence. Oral myiasis is a rare pathology in humans and is associated with poor oral hygiene.
Sandhya Chunilal, Dharshiyani, Sangeeta Panjab, Wanjari, Panjab Vitthalrao, Wanjari, Rajkumar N, Parwani   +3 more
openaire   +2 more sources

Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley   +1 more source

Silencing of long non-coding RNA CCAT2 depressed malignancy of oral squamous cell carcinoma via Wnt/β-catenin pathway

Tumor Biology, 2017
Oral squamous cell carcinoma is a common and lethal malignancy affecting the head and neck region. CCAT2 (colon cancer–associated transcript 2) gene is affiliated with long non-coding RNAs, which are often found to have important regulatory roles in ...
Yuji Ma, Xuanhao Hu, Chao Shang, Ming Zhong, Yan Guo   +4 more
doaj   +1 more source

Investigating resistin like beta (RETNLB) as a tumor promoter for oral squamous cell carcinoma

Head & Face Medicine, 2021
Background Oral cavity cancer ranks the sixth most common malignancy worldwide, of which oral squamous cell carcinoma is the predominant type. This study aimed to investigate the function and the underlying mechanism of resistin like beta (RETNLB) in ...
Hong Jin, Hui Miao, Yuan-Wen Nie, Yang-Yang Lin   +3 more
doaj   +1 more source

Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy

Advanced Materials, EarlyView.
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla, Jacqueline J. Li, Qunzhou Zhang, Korey Patwari, Shihong Shi, Hannah M. Yamagata, Ryann A. Joseph, Briyanna N. Hymms, Sridatta V. Teerdhala, Emily Fitzgerald, Ori Z. Chalom, Kushol Gupta, Mohamad‐Gabriel Alameh, Drew Weissman, Anh D. Le, Michael J. Mitchell   +15 more
wiley   +1 more source

Role of Molecular Targeted Therapeutic Drugs in Treatment of Oral Squamous Cell Carcinoma: Development and Current Strategies—A Review Article

Global Medical Genetics, 2022
Because of active advancement in the field of biomedicine, people have in-depth knowledge of biological nature of malignant tumors and are able to recognized the overexpression of different molecules such as vascular endothelial growth factor receptor ...
Himanshu Singh, Vedant Patel
doaj   +1 more source

Bandgap‐Engineered PtxTey:Ag2Te Composite Quantum Dots Enable Programmable NIR‐II Imaging and Photothermal‐Immune Synergistic Therapy

Advanced Science, EarlyView.
A bandgap‐engineered PtxTey:Ag2Te quantum dot platform enables tunable NIR‐IIb emission for deep‐tissue imaging and mild photothermal therapy. Conjugation with αPD‐L1 confers dual tumor targeting and real‐time monitoring of PD‐L1 dynamics. Mild photothermal modulation induces immune reprogramming, enhancing checkpoint blockade efficacy and achieving ...
Jing Liu, Rui Xu, Quan Wu, Tian‐Xin Xiao, Lai‐Xi Zhao, Lei Sun, Ya‐Wen Zheng, Liang Dong, Zhi‐Quan Tian, Haibo Wang   +9 more
wiley   +1 more source

A circular RNA derived from MMP9 facilitates oral squamous cell carcinoma metastasis through regulation of MMP9 mRNA stability

Cell Transplantation, 2019
Emerging evidence demonstrates that dysregulation of circular RNA is linked to tumorigenesis and aggressive progression. However, its role in oral squamous cell carcinoma remains largely uncharacterized.
Bing Xia, Tao Hong, Xin He, Xinlan Hu, Yongbo Gao   +4 more
doaj   +1 more source