Results 41 to 50 of about 214,541 (306)

Rapamycin enhances the anti-angiogenesis and anti-proliferation ability of YM155 in oral squamous cell carcinoma

Tumor Biology, 2017
YM155, a small molecule inhibitor of survivin, has been studied in many tumors. It has been shown that YM155 inhibited oral squamous cell carcinoma through promoting apoptosis and autophagy and inhibiting proliferation.
Kong-Liang Li, Yu-Fan Wang, Jia-Ruo Qin, Feng Wang, Yong-Tao Yang, Li-Wu Zheng, Ming-Hua Li, Jie Kong, Wei Zhang, Hong-Yu Yang   +9 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Association of Porphyromonas gingivalis-infected oral squamous cell carcinoma cell-secreted exosomal miR-3648-1-p5 with tumor progression

Cancer Cell International
Background Oral squamous cell carcinoma accounts for over 90% of oral malignancies and remains a major global public health concern. Our previous study identified Porphyromonas gingivalis (P.
Xiaorong Tan, Zhangping Tan, Wenyue Xu, Yuchuan Zhou, Wei Wei, Chenxi Li, Muqiu Li, Zhongcheng Gong   +7 more
doaj   +1 more source

Epidemiology and incidence of oral squamous cell carcinoma in the Iraqi population over 5 years (2014–2018)

Health Science Reports, 2023
Background Oral squamous cell carcinoma is one of the most common and life‐threatening neoplasms worldwide, and is responsible for approximately 90% of all oral malignancies. Aim This study was aimed at providing updated information on oral squamous cell
Muhanad L. Alshami, Mohammed Abbood Al‐Maliky, Ali Arkan Alsagban, Ali J. Alshaeli   +3 more
doaj   +1 more source

Squamous Cell Carcinoma of the Oral Tongue: a Single Institution Retrospective Cohort Study From Mansoura University Hospital [PDF]

, 2019
Background: Egyptian hospital–based statistics showed that head & neck carcinomas represent 18% of all cancers and mostly diagnosed at advanced stages.
Halim, A. (Amal), Hamdy, R. (Rasha)
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Investigating resistin like beta (RETNLB) as a tumor promoter for oral squamous cell carcinoma

Head & Face Medicine, 2021
Background Oral cavity cancer ranks the sixth most common malignancy worldwide, of which oral squamous cell carcinoma is the predominant type. This study aimed to investigate the function and the underlying mechanism of resistin like beta (RETNLB) in ...
Hong Jin, Hui Miao, Yuan-Wen Nie, Yang-Yang Lin   +3 more
doaj   +1 more source

Frequency of primary solid malignant neoplasms in both sexes, as seen in our practice [PDF]

, 2007
Background: To determine the frequency of various histologic types of primary solid malignant neoplasms in males and females, in our practice, in a large series of surgical biopdies.
Ahmad, Zubair, Ahmed, Rashida, Ahsan, Aamir, Azad, Najamul Sahar, Hassan, Sheema H., Husain, Akhtar, Kayani, Naila, Khan, Ambreen Nasir, Pervez, Shahid, Yaqoob, Nausheen   +9 more
core   +1 more source

RAB25 expression is epigenetically downregulated in oral and oropharyngeal squamous cell carcinoma with lymph node metastasis [PDF]

, 2016
Oral and oropharyngeal squamous cell carcinoma (OOSCC) have a low survival rate, mainly due to metastasis to the regional lymph nodes. For optimal treatment of these metastases, a neck dissection is required; however, inaccurate detection methods results
Clausen, MJAM, De Meyer, Tim, Denil, Simon, Groen, HJM, Mastik, MF, Melchers, LJ, Roodenburg, JLN, Schuuring, E, Slagter-Menkema, L, Van Criekinge, Wim, van der Laan, BFAM, van der Vegt, B, Wisman, GBA   +12 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source