Results 91 to 100 of about 119,825 (261)

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

A Comparative Study of Bcl-2 Expression in Oral Leukoplakia with Dysplasia, Verrucous Carcinoma, and Oral Squamous Cell Carcinoma

Journal of Pharmacy and Bioallied Sciences
Aim: To study the immunohistochemical expression of Bcl-2 in oral leukoplakia with dysplasia, verrucous carcinoma and oral squamous cell carcinoma(OSCC).
Bireswar Roy, Shivani Saxena, Narayan Tripathi, Mridul Sharma, Deepmala Rana, N Pramukh, Miral Mehta   +6 more
doaj   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Dental Rehabilitation of the Scapular Tip in Maxillary Reconstruction

Head &Neck, EarlyView.
ABSTRACT Introduction The fibula‐free flap has traditionally been utilized to perform dental rehabilitation following maxillectomy. The purpose of this study is to present our experience with dental implantation of the scapula–tip‐free flap in midface reconstruction.
Leba M. Sarkis, John Lee, Karl Cuddy, Brian Rittenberg, Majd Al Mardini, Christopher MKL Yao, Sharon Tzelnick, David Goldstein, Ralph Gilbert, John R. de Almeida   +9 more
wiley   +1 more source

Oral Papillary Squamous Cell Carcinoma and Oral Squamous Cell Carcinoma: A Histopathological and Immunohistochemical Comparative Study

Head and Neck Pathology
Abstract Purpose The aim of the study is to investigate the immunohistochemical expression of both Alpha smooth muscle actin and Transforming Growth Factor beta and compare their expression in oral papillary squamous cell carcinoma with their expression in different histological grades of oral squamous cell carcinoma.
Esraa Ashraf Mahmoud, Mohsen Kazem Abdellatif, Sarah Ahmed Mohammed Mahmoud   +2 more
openaire   +2 more sources

Pattern of Progression of Oral Potentially Malignant Disorders From Real‐World Data: A 24‐Year Study

Head &Neck, EarlyView.
ABSTRACT Background Oral potentially malignant disorder (OPMD) prognostication is limited by uncertainty of which lesions will progress and the aggressiveness of lesion progression. We defined patterns and kinetics of progression in a large cohort of OPMD subjected to serial clinical and histologic examinations. Methods This 24‐year study evaluated the
Subin Surendran, Sumsum P. Sunny, Preethi M. Chathoth, William J. Magner, S. Lynn Sigurdson, Mihai Merzianu, Norbert Sule, Anurag K. Singh, Kimberly E. Wooten, Ryan P. McSpadden, Vishal Gupta, Amritha Suresh, Ashok Z. Samuel, Rohit Bhargava, Praveen N. Birur, Wesley L. Hicks Jr, Moni Abraham Kuriakose   +16 more
wiley   +1 more source

Downregulation of Notch4 – a prognostic marker in distinguishing oral verrucous carcinoma from oral squamous cell carcinoma

Brazilian Journal of Otorhinolaryngology, 2019
Introduction: Oral verrucous carcinoma is a special form of well-differentiated squamous cell carcinoma which possesses specific clinical, morphologic and cytokinetic features that differ from other types of oral cancers and hence diagnosis requires ...
M.K. Harishankar, A. Mathan Mohan, A. Vinod Krishnan, Arikketh Devi   +3 more
doaj   +1 more source

Cigarette Smoke Exposure Attenuates T2R‐Mediated Apoptosis in Head and Neck Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Tobacco use is associated with worse outcomes in head and neck squamous cell carcinoma (HNSCC). Bitter taste receptor (T2R) activation induces apoptosis via calcium‐dependent signaling, and higher T2R expression correlates with increased survival in HNSCC.
Kyle Polen, Sarah Sywanycz, Gavin Turner, Brianna L. Hill, Lily Huang, Zoey A. Miller, Casey Hanna, Lovely Raghav, Devraj Basu, Robert J. Lee, Ryan M. Carey   +10 more
wiley   +1 more source

Treatment‐Related Adverse Events and Health‐Related Quality of Life Associated With Immune Checkpoint Inhibitor Treatment for Mucosal Head and Neck Squamous Cell Carcinoma: A Scoping Review

Head &Neck, EarlyView.
ABSTRACT Background Supportive care needs of patients receiving immune checkpoint inhibitors (ICIs) for head and neck squamous cell carcinoma (HNSCC) are ill‐defined. Hence, known treatment‐related adverse events (TRAEs) and health‐related quality of life (HRQoL) associated with ICI treatment for HNSCC were examined to inform future supportive care ...
N. D. O'Donnell, E. C. Ward, L. R. Wishart, R. Perera, C. Barrett, K. A. Edmiston, E. Mitchell, A. Pigott, R. Pitt, K. Russell, B. A. Chan, R. Ladwa   +11 more
wiley   +1 more source

Comparison of SKA1 serum levels in oral potentially malignant disorders and oral squamous cell carcinoma

Journal of the Pakistan Medical Association
Objective: To compare serum levels of spindle and kinetochore-associated complex subunit 1 in oral potentially malignant disorders and oral squamous cell carcinoma.
Samreen Khan, Muhammad Mohiuddin Alamgir, Uzma Bukhari, Muhammad Shuja Farrukh   +3 more
doaj   +1 more source