Results 1 to 10 of about 1,807,811 (158)

Transgenic Schizochytrium as a Promising Oral Vaccine Carrier: Potential Application in the Aquaculture Industry [PDF]

Marine Drugs
Schizochytrium limacinum SR21, a kind of eukaryotic heterotrophic organism rich in unsaturated fatty acids, is an emerging microbial alternative to fish oil. The dietary inclusion of 15% SR21 was optimal for the growth performance of zebrafish.
Ke Ma, Lei Deng, Yuanjie Wu, Yuan Gao, Jianhua Fan, Haizhen Wu   +5 more
doaj   +2 more sources

Modulation of oral vaccine efficacy by the gut microbiota [PDF]

npj Vaccines
Oral vaccines are potential options for preventing global pandemics because of their ability to elicit systemic and mucosal immunity and the high degree of compliance among individuals for oral vaccines.
Yingying Hou, Jinqi Li, Yue Wu
doaj   +2 more sources

Oral Vaccines: A Better Future of Immunization

Vaccines, 2023
Oral vaccines are gaining more attention due to their ease of administration, lower invasiveness, generally greater safety, and lower cost than injectable vaccines. This review introduces certified oral vaccines for adenovirus, recombinant protein-based,
Keith Wai-Yeung Kwong, Ying Xin, Nelson Cheuk-Yin Lai, Johnny Chun-Chau Sung, Kam-Chau Wu, Yusuf Khwaja Hamied, Eric Tung-Po Sze, Dominic Man-Kit Lam   +7 more
doaj   +3 more sources

A Systems Biology Approach Identifies B Cell Maturation Antigen (BCMA) as a Biomarker Reflecting Oral Vaccine Induced IgA Antibody Responses in Humans

Frontiers in Immunology, 2021
Vaccines against enteric diseases could improve global health. Despite this, only a few oral vaccines are currently available for human use. One way to facilitate such vaccine development could be to identify a practical and relatively low cost biomarker
Lynda Mottram, Anna Lundgren, Ann-Mari Svennerholm, Susannah Leach, Susannah Leach   +4 more
doaj   +1 more source

An oral cancer vaccine using a Bifidobacterium vector suppresses tumor growth in a syngeneic mouse bladder cancer model

Molecular Therapy: Oncolytics, 2021
Cancer immunotherapy using immune-checkpoint inhibitors (ICIs) such as PD-1/PD-L1 inhibitors has been well established for various types of cancer. Monotherapy with ICIs, however, can achieve a durable response in only a subset of patients.
Koichi Kitagawa, Maho Tatsumi, Mako Kato, Shota Komai, Hazuki Doi, Yoshiko Hashii, Takane Katayama, Masato Fujisawa, Toshiro Shirakawa   +8 more
doaj   +1 more source

Vibrio cholerae, classification, pathogenesis, immune response, and trends in vaccine development

Frontiers in Medicine, 2023
Vibrio cholerae is the causative agent of cholera, a highly contagious diarrheal disease affecting millions worldwide each year. Cholera is a major public health problem, primarily in countries with poor sanitary conditions and regions affected by ...
David A. Montero, Roberto M. Vidal, Roberto M. Vidal, Juliana Velasco, Juliana Velasco, Sergio George, Yalda Lucero, Yalda Lucero, Leonardo A. Gómez, Leandro J. Carreño, Leandro J. Carreño, Richard García-Betancourt, Miguel O’Ryan   +12 more
doaj   +1 more source

Oral Immunization of Larvae and Juvenile of Lumpfish (Cyclopterus lumpus) against Vibrio anguillarum Does Not Influence Systemic Immunity

Vaccines, 2021
Vibrio anguillarum, a marine bacterial pathogen that causes vibriosis, is a recurrent pathogen of lumpfish (Cyclopterus lumpus). Lumpfish is utilized as a cleaner fish in the Atlantic salmon (Salmo salar) aquaculture in the North Atlantic region because ...
My Dang, Trung Cao, Ignacio Vasquez, Ahmed Hossain, Hajarooba Gnanagobal, Surendra Kumar, Jennifer R. Hall, Jennifer Monk, Danny Boyce, Jillian Westcott, Javier Santander   +10 more
doaj   +1 more source

Development of a Potential Yeast-Based Vaccine Platform for Theileria parva Infection in Cattle

Frontiers in Immunology, 2021
East Coast Fever (ECF), caused by the tick-borne apicomplexan parasite Theileria parva, remains one of the most important livestock diseases in sub-Saharan Africa with more than 1 million cattle dying from infection every year.
Shan Goh, Jeannine Kolakowski, Angela Holder, Mark Pfuhl, Daniel Ngugi, Keith Ballingall, Kata Tombacz, Dirk Werling   +7 more
doaj   +1 more source

Live-Attenuated Salmonella-Based Oral Vaccine Candidates Expressing PCV2d Cap and Rep by Novel Expression Plasmids as a Vaccination Strategy for Mucosal and Systemic Immune Responses against PCV2d

Vaccines, 2023
Oral vaccines are highly envisaged for veterinary applications due to their convenience and ability to induce protective mucosal immunity as the first line of defense.
Khristine Kaith Sison Lloren, John Hwa Lee   +1 more
doaj   +1 more source

Efficacy of Oral Vaccine against Classical Swine Fever in Wild Boar and Estimation of the Disease Dynamics in the Quantitative Approach

Viruses, 2021
Classical swine fever virus (CSFV) in the wild boar population has been spreading in Japan, alongside outbreaks on pigs, since classical swine fever (CSF) reemerged in September 2018.
Enkhbold Bazarragchaa, Norikazu Isoda, Taksoo Kim, Madoka Tetsuo, Satoshi Ito, Keita Matsuno, Yoshihiro Sakoda   +6 more
doaj   +1 more source