Live-Attenuated Salmonella-Based Oral Vaccine Candidates Expressing PCV2d Cap and Rep by Novel Expression Plasmids as a Vaccination Strategy for Mucosal and Systemic Immune Responses against PCV2d [PDF]
Vaccines, 2023 Oral vaccines are highly envisaged for veterinary applications due to their convenience and ability to induce protective mucosal immunity as the first line of defense.
Khristine Kaith Sison Lloren +1 more
doaj +2 more sources
Transgenic Schizochytrium as a Promising Oral Vaccine Carrier: Potential Application in the Aquaculture Industry [PDF]
Marine DrugsSchizochytrium limacinum SR21, a kind of eukaryotic heterotrophic organism rich in unsaturated fatty acids, is an emerging microbial alternative to fish oil. The dietary inclusion of 15% SR21 was optimal for the growth performance of zebrafish.
Ke Ma +5 more
doaj +2 more sources
Modulation of oral vaccine efficacy by the gut microbiota [PDF]
npj VaccinesOral vaccines are potential options for preventing global pandemics because of their ability to elicit systemic and mucosal immunity and the high degree of compliance among individuals for oral vaccines.
Yingying Hou, Jinqi Li, Yue Wu
doaj +2 more sources
Application of Recombinant Lactic Acid Bacteria (LAB) Live Vector Oral Vaccine in the Prevention of F4+ Enterotoxigenic Escherichia coli [PDF]
VaccinesEnterotoxigenic Escherichia coli (ETEC) causes severe diarrhea in piglets. The current primary approach for ETEC prevention and control relies on antibiotics, as few effective vaccines are available.
Jiangxu Yu +11 more
doaj +2 more sources
Frontiers in Immunology, 2021 Vaccines against enteric diseases could improve global health. Despite this, only a few oral vaccines are currently available for human use. One way to facilitate such vaccine development could be to identify a practical and relatively low cost biomarker
Lynda Mottram +4 more
doaj +1 more source
Molecular Therapy: Oncolytics, 2021 Cancer immunotherapy using immune-checkpoint inhibitors (ICIs) such as PD-1/PD-L1 inhibitors has been well established for various types of cancer. Monotherapy with ICIs, however, can achieve a durable response in only a subset of patients.
Koichi Kitagawa +8 more
doaj +1 more source
Vibrio cholerae, classification, pathogenesis, immune response, and trends in vaccine development
Frontiers in Medicine, 2023 Vibrio cholerae is the causative agent of cholera, a highly contagious diarrheal disease affecting millions worldwide each year. Cholera is a major public health problem, primarily in countries with poor sanitary conditions and regions affected by ...
David A. Montero +12 more
doaj +1 more source
Vaccines, 2021 Vibrio anguillarum, a marine bacterial pathogen that causes vibriosis, is a recurrent pathogen of lumpfish (Cyclopterus lumpus). Lumpfish is utilized as a cleaner fish in the Atlantic salmon (Salmo salar) aquaculture in the North Atlantic region because ...
My Dang +10 more
doaj +1 more source
Development of a Potential Yeast-Based Vaccine Platform for Theileria parva Infection in Cattle
Frontiers in Immunology, 2021 East Coast Fever (ECF), caused by the tick-borne apicomplexan parasite Theileria parva, remains one of the most important livestock diseases in sub-Saharan Africa with more than 1 million cattle dying from infection every year.
Shan Goh +7 more
doaj +1 more source
Production of a subunit vaccine candidate against porcine post-weaning diarrhea in high-biomass transplastomic tobacco [PDF]
, 2012 Post-weaning diarrhea (PWD) in piglets is a major problem in piggeries worldwide and results in severe economic losses. Infection with Enterotoxigenic Escherichia coli (ETEC) is the key culprit for the PWD disease.
Cox, Eric +5 more
core +8 more sources