Results 51 to 60 of about 690,605 (328)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Ontological imagination: transcending methodological solipsism and the promise of interdisciplinary studies [PDF]
, 2013 This text is a presentation of the notion of ontological imagination. It constitutes an attempt to merge two traditions: critical sociology and science and technology studies - STS.
Nowak, Andrzej W.
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Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence
Pediatric Blood &Cancer, EarlyView.
Gabriele Mortari +9 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Technauriture as an Educational Tool in South Africa
Nordic Journal of African Studies, 2016 This article seeks to situate the importance of orality in southern African communities within the paradigm of Technauriture, that being the intersection of technology, auriture and literature and how it relates to imparting educational messages within ...
Russell H. Kaschula
doaj +1 more source
Understanding Cognition Across Modalities for the Assessment of Digital Resources [PDF]
, 2015 Drawing from the theories of the cognitive process, this paper explores the transmission, retention and transformation of information across oral, written, and digital modes of communication and how these concepts can be used to examine the assessment of
Colon, Valeriana
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Western Journal of Emergency Medicine, 2015 A 35-year-old male presented with lower gum pain associated with fever, chills, and sore throat. His medical history included intravenous drug use, human immunodeficiency virus infection, and hepatitis C. Physical exam revealed tachycardia, a temperature of 38.9°C, anterior cervical lymphadenopathy, halitosis, an edematous lower lip, and purulent ...
Fetterolf, Brandon +2 more
openaire +5 more sources
How to constitute an archive of oral memory and identity within the framework of a.P.T.O.: a few methodological proposals [PDF]
, 2000 In this paper I will focus on a few problems relating to the cataloguing of anthropological materials concerning the specificity of demo-ethnological and anthropological disciplines like context, confidentiality, the role of the ethnographer and the ...
Orsatti, Cristina
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