Results 101 to 110 of about 1,159,608 (316)

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

open access: yesMolecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna   +8 more
wiley   +1 more source

Orange County Voter Registration, Orlando, District 1, 1914-1924 [PDF]

open access: yes, 1914
Orange County Voter Registration, Orlando, District 1, 1914-24, Poll tax dates: 1922-23, Alphabet covered: A-K. Contains entries for: voter name, party affiliation, poll tax paid, occupation, age, race, residence, signature of supervisor or deputy ...
Orange County
core  

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

Orange County Voter Registration, Maitland, District 4, 1914-1924 [PDF]

open access: yes, 1914
Orange County Voter Registration, Maitland, District 4, 1914-1924, Poll tax dates: 1919-1924, Alphabet covered: A-H, J-P, R-T, V, W. Contains entries for: voter name, age, race, poll tax paid, occupation, date of registration, number of certificate ...
Orange County
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Orange County Voter Registration, Fairvilla, District 8, 1922-1924 [PDF]

open access: yes, 1922
Orange County Voter Registration, Fairvilla, District 8, 1922-24, Poll tax dates: 1922-24, Alphabet covered: A-C, E-H, J-M, P, R, S, W. Contains entries for: voter name, party affiliation, poll tax paid, occupation, age, race, residence.
Orange County
core  

Apprentissages scientifiques : ce qui se construit et ce qui se transmet

open access: yesRecherches en Éducation, 2007
Nous discutons ici des relations entre construction (par les élèves) et transmission (par le professeur) dans les apprentissages scientifiques. Pour cela nous présentons trois cas où ces relations sont différentes.
Christian Orange
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Orange County Voter Registration, Gotha, District 14, 1922-1924 [PDF]

open access: yes, 1922
Orange County Voter Registration, Gotha, District 14, 1922-1924, Poll tax dates:1922-1923, Alphabet covered:A-N, P, R-T, V, W. Contains entries for: voter name, poll tax paid, occupation, age, race, residence, signature of supervisor or deputy.
Orange County
core  

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