Results 61 to 70 of about 637,742 (295)

DUS characterization of muskmelon (Cucumis melo) varieties

open access: yesThe Indian Journal of Agricultural Sciences, 2015
The present study was carried out for morphological characterization of twelve reference varieties of muskmelon (Cucumis melo L.) collected from ICAR institutes and SAUs to validate DUS testing guidelines using plant descriptors adopted from the DUS ...
B R CHOUDHARY   +3 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Innovation and Entrepreneurship: A Colour Economy Glance [PDF]

open access: yesSHS Web of Conferences
This article introduces the topic of the Colour Economy as a set of new economic paradigms that seek to respond to global challenges such as sustainability, technological transformation and social inclusion.
Estrada Salvador   +4 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Multivariate analysis of phenotypic diversity in Moroccan orange accessions (Citrus sinensis L. Osbeck) from the El Menzeh collection

open access: yesAfrican and Mediterranean Agricultural Journal - Al Awamia
The morpho-pomological characteristics of 65 traditional orange accessions (Citrus sinensis L. Osbeck) were studied in the plantation of the El Menzeh experimental field of INRA.
Ouiam Chetto   +4 more
doaj   +1 more source

Genetic and ultrastructural studies on an orange coloured chlorophyll mutant of winter rye (Secale cereale L.)

open access: yesActa Societatis Botanicorum Poloniae, 2014
The feature of the orange colour of young seedlings, which appeared in inbred generation S2 of a short straw form of winter rye cultivated in Jeleniec is described.
Helena Kubicka   +3 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

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