Results 91 to 100 of about 32,107 (257)

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Florida, Picking Oranges

, 1900
Two women picking oranges from their orange tree.https://digitalcommons.usf.edu/dunn_postcards/1974/thumbnail ...
Dunn, Hampton
core  

Consumer Preferences in Traditional Markets Regarding Purchase Interest in Local Oranges and Imported Oranges in Surakarta

Oranges are one of the horticultural commodities that play an important role in fulfilling community nutritional needs and have high economic value. The increase of orange consumption in Indonesia has not always been accompanied by stable local orange ...
Muharom Zuhri Abdulloh, Agustono Agustono, Sugiharti Mulya Handayani   +2 more
core   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Men Packing Oranges

, 1912
Syria. Jaffa. Workers packing oranges for shipment (1912).https://digitalcommons.brockport.edu/syria_slides/1065/thumbnail ...
Keystone View Company
core   +1 more source

Picking Oranges in Florida

, 1900
Pickers harvesting ripened oranges in a grove.https://digitalcommons.usf.edu/dunn_postcards/2867/thumbnail ...
Dunn, Hampton
core  

Multivariate polynomial splines on generalized oranges [PDF]

We consider spaces of multivariate splines defined on a particular type of simplicial partitions that we call (generalized) oranges. Such partitions are composed of a finite number of maximal faces with exactly one shared medial face.
Nelly Villamizar
core   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Oranges Are Not the Only Fruit

Winner of the Whitbread Prize for best first fiction, Oranges Are Not the Only Fruit is a coming-out novel from Winterson, the acclaimed author of The Passion and Sexing the Cherry.
Winterson, Jeanette.
core