Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Implementation of AlexNet and Xception Architectures for Disease Detection in Orange Plants
Oranges are one of Indonesia's primary horticultural commodities, with production increasing each year. However, pest and disease infestations often go undetected, leading to significant reductions in crop yields.
Venus Al Fatah, Moh. Ali Romli
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Multiresidual gas chromatography-tandem mass spectrometry method for determination of plant protection product residues in fruit [PDF]
A multiresidual method for the determination of 29 active substances was developed and validated. Acetone, petroleum ether and dichloromethane were used for extraction, and a gas chromatograph coupled with a tandem mass spectrometer was used for ...
Helena BAŠA ČESNIK
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Growth inhibition of Penicillium digitatum by antagonistic microorganisms isolated from various parts of orange tree [PDF]
Penicillium digitatum (Pers.:Fr) Sacc. is the major cause of green mold disease in orange trees grown for orange production industry in Thailand. In this study, antagonistic microorganisms were isolated from various parts of healthy orange trees. A total
Wasu Pathom-aree
doaj
New late-season navel orange varieties evaluated for quality characteristics
New early- and late-maturing navel orange varieties have expanded the navel orange season for California's domestic and export fresh-fruit market.
Tracy Kahn, Ottillia Bier, Robert Beaver
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
ESTUDO DA ORIENTAÇÃO DE LARANJAS IMERSAS EM ÁGUA
RESUMO À medida que o custo de métodos tradicionais de transporte mecânico ou manual aumenta, existe a possibilidade de que o transporte hidráulico de laranjas em canais, como já é empregado em algumas indústrias nacionais, se torne economicamente ...
Maria Elita Duarte Braga +1 more
doaj +1 more source

