Results 81 to 90 of about 361,982 (343)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Pengantaraan Orang-orang Kudus

open access: yesLux et Sal
This article wants to explore the historical and doctrinal basis for the practice of praying through the intercession of saints, which is commonly found in the Catholic Church. For that purpose, it will study the historical context of its origin and its doctrinal basis originating from the documents of councils.
openaire   +1 more source

How effective is the EU's import regime for oranges? [PDF]

open access: yes
EU imports of oranges are restricted not only by ad valorem tariffs but also by the entry price system establishing a minimum import price. In addition, the EU applies a comprehensive system of trade preferences.
Goetz, Linde, Grethe, Harald
core   +1 more source

Early Detection of Freeze Damage in Navelate Oranges with Electrochemical Impedance Spectroscopy

open access: yesItalian National Conference on Sensors, 2018
The early detection of freeze damage in Navelate oranges (Citrus sinensis L. Osbeck) was studied using electrochemical impedance spectroscopy (EIS), which is associated with a specific double-needle sensor.
Emma Serrano-Pallicer   +4 more
semanticscholar   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Demand relationships in orange exports to Russia: a differential demand system approach focusing on Egypt

open access: yesAgricultural and Food Economics, 2016
Recent years have witnessed closer diplomatic relations between Egypt and Russia, which have led to significant growth in the countries’ bilateral agricultural trade.
Assem Abu Hatab
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Cytological and molecular characterization of carotenoid accumulation in normal and high-lycopene mutant oranges

open access: yesScientific Reports, 2017
Ripe Cara Cara sweet orange contains 25 times as much carotenoids in flesh as Newhall sweet orange, due to high accumulation of carotenes, mainly phytoene, lycopene and phytofluene.
Peng Lu   +6 more
semanticscholar   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Are Pesticide Residues Found in the Oranges Produced in Sari? [PDF]

open access: yesJournal of Mazandaran University of Medical Sciences
Background and purpose: Today, ensuring food security for the inhabitants of the earth, and preserving agricultural production from destruction due to drought, pests, and diseases, seems more necessary than ever.
Narges Mazloomi   +6 more
doaj  

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