Results 91 to 100 of about 1,050,854 (350)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
On the gauge orbit space stratification (a review)
, 2002 First, we review the basic mathematical structures and results concerning the gauge orbit space stratification. This includes general properties of the gauge group action, fibre bundle structures induced by this action, basic properties of the ...
Rudolph, G. +2 more
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Subconjunctival and Orbital (Twin) Cysticercosis in a Child
Journal of Ophthalmic & Vision Research, 2019 This article is a Photo Essay and does not include an Abstract.
Kasturi Bhattacharjee +3 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
VisualR: A novel and scalable solution for assessing visual function using virtual reality
Digital HealthObjective Diagnosis and treatment of progressive eye diseases require effective monitoring of visual structure and function. However, current methods for measuring visual function are limited in accuracy, reliability, and usability.
Federica Sozzi +7 more
doaj +1 more source
Current-induced torques in textured Rashba ferromagnets
, 2012 In systems with small spin-orbit coupling, current-induced torques on the magnetization require inhomogeneous magnetization textures. For large spin-orbit coupling, such torques exist even without gradients in the magnetization direction.
E. I. Rashba +2 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
STar-DETR: A Lightweight Real-Time Detection Transformer for Space Targets in Optical Sensor Systems
SensorsOptical sensor systems are essential for space target detection. However, previous studies have prioritized detection accuracy over model efficiency, limiting their deployment on resource-constrained sensors.
Yao Xiao +5 more
doaj +1 more source
Why is the Moon synchronously rotating?
, 2013 If the Moon's spin evolved from faster prograde rates, it could have been captured into a higher spin-orbit resonance than the current 1:1 resonance. At the current value of orbital eccentricity, the probability of capture into the 3:2 resonance is as ...
Makarov, Valeri V.
core +1 more source