Results 91 to 100 of about 1,818,861 (299)

Reduction and analysis of one-way laser ranging data from ILRS ground stations to LRO [PDF]

, 2013
One-way LR (Laser Ranging) is being performed routinely from ILRS (International Laser Ranging Service) ground stations to LOLA (Lunar Orbiter Laser Altimeter), onboard NASA’s LRO (Lunar Reconnaissance Orbiter).
Schreiber, Ulli, Smith, David, Neumann, Gregory, McGarry, Jan, Mao, Dandan, Torrence, Mark, Oberst, Jürgen, Hussmann, Hauke, Zuber, Maria, Mazarico, Erwan, Bauer, Sven, Gläser, Philipp   +11 more
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Impact of GNSS orbit modeling on LEO orbit and gravity field determination [PDF]

, 2017
On January 4, 2015 the Center for Orbit Determination in Europe (CODE) changed the solar radiation pressure modeling for GNSS satellites to an updated version of the empirical CODE orbit model (ECOM).
Arnold, Daniel, Susnik, Andreja, Dach, Rolf, Meyer, Ulrich, Jäggi, Adrian   +4 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

FedSat Orbit Determination: Results From Daily GPS Flight Code Observations [PDF]

, 2003
The Australian Federation Satellite, FedSat, was successfully launched into a 780-km low-earth orbit on 14 December 2002. Since then, the onboard Blackjack GPS receiver has operated on a duty cycle basis, providing effective data sets at an average of 10
Enderle, Werner, Feng, Yanming, Zhou, Ning   +2 more
core  

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Analysis of Orbit Accuracy for Non-cooperative Earth-Orbiting Objects

Open Astronomy, 2019
The atmospheric resistance and solar radiation pressure are the main sources of non-gravitational perturbations in orbit determination and prediction of non-cooperative earth-orbiting objects.
Jianrong Chen, Junfeng Li
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Precise orbit determination of Haiyang-2 using satellite laser ranging

, 2013
With the successful launch and official commissioning of China's first dynamic ocean environment satellite Haiyang-2 (HY-2), China's capabilities for oceanic environment monitoring and oceanic resource detecting have been further improved and enhanced ...
Wu Bin, Zhao Gang, Zhou XuHua
core