Results 101 to 110 of about 3,365,879 (300)

Summary of Lunar Constellation Navigation and Orbit Determination Technology

Aerospace
The Moon is the closest celestial body to the Earth. Its rich unique resources are an important supplement to the Earth’s resources and have a profound impact on the sustainable development of human society.
Xiao Zhang, Zhaowei Sun, Xiao Chen, Linxin Pan, Yubin Zhong   +4 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Overview on Space-Based Optical Orbit Determination Method Employed for Space Situational Awareness: From Theory to Application

Photonics
Leveraging space-based optical platforms for space debris and defunct spacecraft detection presents several advantages, including a wide detection range, immunity to cloud cover, and the ability to maintain continuous surveillance on space targets.
Zhe Zhang, Gaopeng Zhang, Jianzhong Cao, Cheng Li, Weining Chen, Xin Ning, Zheng Wang   +6 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Space-ground collaborative weighted orbit determination and prediction method for resource-constrained space-ground communication scenarios

天地一体化信息网络
Precise orbit determination is fundamental to ensuring the reliable operation of low Earth orbit satellite services such as communication, navigation, and remote sensing. Under resource-constrained space-ground communication conditions, traditional orbit
Deng Ruofan, Wang Haoyu, Wei Fengmei, Qin Lin, Ning Kai   +4 more
doaj  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

First Use of Laser Ranging to Surface Retroreflectors for Orbit Determination: LRO-LOLA at the Moon

The Planetary Science Journal
We document the first operational demonstration of two-way spacecraft-to-surface laser ranging using Laser Retroreflector Arrays (LRAs) for orbit determination (OD) of the Lunar Reconnaissance Orbiter (LRO).
G. Cascioli, E. Mazarico, D. R. Cremons, M. K. Barker, D. Mao, S. Goossens, V. Viswanathan, S. Bertone, K. Jha, F. G. Lemoine, X. Sun, J. W. Head, D. E. Smith, M. T. Zuber   +13 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source