Results 121 to 130 of about 22,697 (311)

Reduction and analysis of one-way laser ranging data from ILRS ground stations to LRO

, 2013
One-way LR (Laser Ranging) is being performed routinely from ILRS (International Laser Ranging Service) ground stations to LOLA (Lunar Orbiter Laser Altimeter), onboard NASA’s LRO (Lunar Reconnaissance Orbiter).
Schreiber, Ulli, Smith, David, Neumann, Gregory, McGarry, Jan, Mao, Dandan, Torrence, Mark, Oberst, Jürgen, Hussmann, Hauke, Zuber, Maria, Mazarico, Erwan, Bauer, Sven, Gläser, Philipp   +11 more
core  

First Use of Laser Ranging to Surface Retroreflectors for Orbit Determination: LRO-LOLA at the Moon

The Planetary Science Journal
We document the first operational demonstration of two-way spacecraft-to-surface laser ranging using Laser Retroreflector Arrays (LRAs) for orbit determination (OD) of the Lunar Reconnaissance Orbiter (LRO).
G. Cascioli, E. Mazarico, D. R. Cremons, M. K. Barker, D. Mao, S. Goossens, V. Viswanathan, S. Bertone, K. Jha, F. G. Lemoine, X. Sun, J. W. Head, D. E. Smith, M. T. Zuber   +13 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Realtime Precise Orbit Determination Technology for LEO Mega-Constellation

天地一体化信息网络
Supported by GNSS, it analyzed the advantages and disadvantages of solving LEO satellite orbit on the ground or onboard the satellites.The high-fidelity non-conservative force models were applied to the real-time orbit determination algorithm.To separate
Zhen LI, Chuang SHI
doaj   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

FedSat Orbit Determination: Results From Daily GPS Flight Code Observations

, 2003
The Australian Federation Satellite, FedSat, was successfully launched into a 780-km low-earth orbit on 14 December 2002. Since then, the onboard Blackjack GPS receiver has operated on a duty cycle basis, providing effective data sets at an average of 10
Enderle, Werner, Feng, Yanming, Zhou, Ning   +2 more
core  

Doppler Orbit Determination of Deep Space Probes by the Bernese GNSS Software: First Results of the Combined Orbit Determination from DSN and Inter-Satellite Ka-Band Data from the Grail Mission [PDF]

, 2015
Navigation of deep space probes is most commonly operated using the spacecraft Doppler tracking technique. Orbital parameters are determined from a series of repeated measurements of the frequency shift of a microwave carrier over a given integration ...
Arnold, Daniel, Bertone, Stefano, Beutler, Gerhard, Mervart, Leos, Jäggi, Adrian   +4 more
core  

Bistatic SAR Imaging and Precise Orbit Determination Using Geostationary Telecommunication Satellites

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
SAR satellite missions from geostationary orbits (GEOSAR) would offer the short revisit times required in the observation of fast phenomena. Ground-based multiple baseline interferometry is a technique under study for precise orbit determination of GEO ...
Xavier Carreno-Megias, Jorge Nicolas-Alvarez, Antoni Broquetas, Albert Aguasca, Joan Cuy-Saques, Marius Gutierrez   +5 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source