Results 121 to 130 of about 202,602 (307)

The iterative solution of the problem of orbit determination using Chebyshev series [PDF]

A method of orbit determination is investigated which employs Picard iteration and Chebyshev series. The method is applied to the problem of determining the orbit of an earth satellite from range and range-rate observations contaminated by noise.
Feagin, T.
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

GOES I/M image navigation and registration [PDF]

Image Navigation and Registration (INR) is the system that will be used on future Geostationary Operational Environmental Satellite (GOES) missions to locate and register radiometric imagery data.
Fiorello, J. L., Jr., Kelly, K. A., Oh, I. H., Ranne, L.   +3 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Bistatic SAR Imaging and Precise Orbit Determination Using Geostationary Telecommunication Satellites

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
SAR satellite missions from geostationary orbits (GEOSAR) would offer the short revisit times required in the observation of fast phenomena. Ground-based multiple baseline interferometry is a technique under study for precise orbit determination of GEO ...
Xavier Carreno-Megias, Jorge Nicolas-Alvarez, Antoni Broquetas, Albert Aguasca, Joan Cuy-Saques, Marius Gutierrez   +5 more
doaj   +1 more source

Special studies of AROD system concepts and designs [PDF]

Signal to noise ratios in airborne range and orbit determination system, and carrier and range loop performance ...
Baghdady, E. J., Kruse, K. W., Meer, S. A.   +2 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Ionospheric refraction effects on orbit determination using the orbit determination error analysis system [PDF]

The influence of ionospheric refraction on orbit determination was studied through the use of the Orbit Determination Error Analysis System (ODEAS). The results of a study of the orbital state estimate errors due to the ionospheric refraction corrections,
Dunham, J. B., Kelbel, D. A., Lee, T., Mistretta, G. D., Yee, C. P.   +4 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Navigation strategy and filter design for solar electric missions [PDF]

Methods which have been proposed to improve the navigation accuracy for the low-thrust space vehicle include modifications to the standard Sequential- and Batch-type orbit determination procedures and the use of inertial measuring units (IMU) which ...
Hagar, H., Jr., Tapley, B. D.
core   +1 more source