Results 141 to 150 of about 1,818,861 (299)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Doppler Orbit Determination of Deep Space Probes by the Bernese GNSS Software: First Results of the Combined Orbit Determination from DSN and Inter-Satellite Ka-Band Data from the Grail Mission [PDF]

open access: yes, 2015
Navigation of deep space probes is most commonly operated using the spacecraft Doppler tracking technique. Orbital parameters are determined from a series of repeated measurements of the frequency shift of a microwave carrier over a given integration ...
Arnold, Daniel   +4 more
core   +2 more sources

Influence of Time Intervals: Comparative Analysis of Short-Arc Orbit Determination for GEO Satellites Using AER and RNG Methods

open access: yesHavacılık ve Uzay Teknolojileri Dergisi
Short arc orbit determination for GEO satellites is useful when there are gaps or incomplete data due to limited time or other factors. Full cycle orbit determination requires continuous data over the entire orbit cycle, which may not always be available.
Ümit Cezmi Yılmaz   +3 more
doaj  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Perturbations in the optimized boundary value initial orbit determination approach [PDF]

open access: yes, 2019
One of the increasing threats to functional spacecraft around Earth is that of Space Debris. The risks that it poses for current and future space operations due to collisions are growing in an exponential manner.
Schildknecht, Thomas   +2 more
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Precise Orbit Determination and Prediction of the ISS in the frame of the ACES Mission [PDF]

open access: yes, 2012
Helm, Achim   +3 more
core   +1 more source

Orbit determination [PDF]

open access: yes, 1965
Orbit determination for artificial satellites and ...
Siry, J. W.
core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Orbit determination of FedSat based on GPS receiver position solutions – first results [PDF]

open access: yes, 2003
On 14th December 2002, the Australian small satellite FedSat was launched with a Japanese HII-A rocket into an 800 km sun-synchronous orbit with an inclination of 98.6 degrees.
Enderle, Werner   +2 more
core  

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