Results 71 to 80 of about 3,161,815 (352)

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

PPP-based Swarm kinematic orbit determination [PDF]

open access: yesAnnales Geophysicae, 2018
The Swarm mission of the European Space Agency (ESA) offers excellent opportunities to study the ionosphere and to provide temporal gravity field information for the gap between the Gravity Recovery and Climate Experiment (GRACE) and its follow-on ...
L. Ren, S. Schön
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Multi-GNSS orbit determination using satellite laser ranging

open access: yesJournal of Geodesy, 2018
Galileo, BeiDou, QZSS, and NavIC are emerging global navigation satellite systems (GNSSs) and regional navigation satellite systems all of which are equipped with laser retroreflector arrays for range measurements.
G. Bury, K. Sośnica, R. Zajdel
semanticscholar   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

open access: yesFEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii   +8 more
wiley   +1 more source

ICESat‐2 Precision Orbit Determination

open access: yesEarth and Space Science, 2021
The ICESat‐2 Precision Orbit Determination (POD) system computes the precise position of the laser altimeter instrument in inertial space, a measurement necessary for accurate geolocation of individual photon surface returns.
T. C. Thomas   +4 more
doaj   +1 more source

An independent determination of Fomalhaut b's orbit and the dynamical effects on the outer dust belt [PDF]

open access: yes, 2013
The nearby star Fomalhaut harbours a cold, moderately eccentric dust belt with a sharp inner edge near 133 au. A low-mass, common proper motion companion (Fom b), was discovered near the inner edge and was identified as a planet candidate that could ...
Augereau, Jean-Charles   +9 more
core   +6 more sources

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