Results 71 to 80 of about 318,817 (173)

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

FEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

High-precision GPS orbit determination by integrating the measurements from regional ground stations and LEO onboard receivers

Satellite Navigation
High-precision Global Navigation Satellite System (GNSS) orbit and clock products are crucial for precise applications. An evenly distributed global network enables continuous tracking for GNSS satellites, while a regional network may result in tracking ...
Kai Li, Chengpan Tang, Shanshi Zhou, Xiaogong Hu, Xuhua Zhou   +4 more
doaj   +1 more source

Orbit graphs and face-transitivity of k-orbit polytopes [PDF]

arXiv, 2012
The orbit graph of a k-orbit polytope is a graph on k nodes that shows how the flag orbits are related by flag adjacency. Using orbit graphs, we classify k-orbit polytopes and determine when a k-orbit polytope is i-transitive. We then provide an explicit classification of three-orbit polytopes, and we describe a generating set for their automorphism ...
arxiv  

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

Analysis of Orbit Accuracy for Non-cooperative Earth-Orbiting Objects

Open Astronomy, 2019
The atmospheric resistance and solar radiation pressure are the main sources of non-gravitational perturbations in orbit determination and prediction of non-cooperative earth-orbiting objects.
Jianrong Chen, Junfeng Li
doaj   +1 more source

Local orbit types of the isotropy representations for semisimple pseudo-Riemannian symmetric spaces [PDF]

https://doi.org/10.1016/j.difgeo.2014.12.002, 2013
We list up all the possible local orbit types of hyperbolic or elliptic orbits for the isotropy representations of semisimple pseudo-Riemannian symmetric spaces. It is key to give a recipe to determine the local orbit types of hyperbolic principal orbits by using three kind of restricted root systems and Satake diagrams associated with semisimple ...
arxiv  

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Orbit Determination Error Analysis for the KOMPSAT [PDF]

Journal of Astronomy and Space Sciences, 1998
Orbit error analysis was performed for the GPS navigation solutions and ground station tracking data of the KOMPSAT (Korea Multi-Purpose SATellite), which will be launched in 1999 for cartography of Korean peninsula as main mission. A least square method
Jeong-Sook Lee, Byoung-Sun Lee
doaj  

Kernel Embedding Approaches to Orbit Determination of Spacecraft Clusters [PDF]

arXiv, 2018
This paper presents a novel formulation and solution of orbit determination over finite time horizons as a learning problem. We present an approach to orbit determination under very broad conditions that are satisfied for n-body problems. These weak conditions allow us to perform orbit determination with noisy and highly non-linear observations such as
arxiv